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Volume 22 (11); 2025
Research Papers
Doxycycline Enhances Anticancer Activity of Zoledronic Acid via Inducing ROS and Autophagy in Osteosarcoma Cell Lines Yi-An Li, Hsuan-Ying Chen, Chien-Sheng Hsu, Shun-Cheng Tseng, Eric Hwang, Cheng-Pu Hsieh, Shih-Chieh Hung, Yi-Fu Huang
Int. J. Med. Sci. 2025; 22(11): 2560-2569. doi:10.7150/ijms.108086
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Global, regional, and national burden of gastritis and duodenitis from 1990 to 2021 with projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 Lufei Wang, Wei Jiang, Hui Li
Int. J. Med. Sci. 2025; 22(11): 2570-2582. doi:10.7150/ijms.109762
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The combination of PF-429242 and chloroquine triggers pH-dependent cell death in hepatocellular carcinoma cells Jiunn-Chang Lin, Tun-Sung Huang, Yan-Bin Chen, Pao-Shu Wu, Tsang-Pai Liu, Pei-Ming Yang
Int. J. Med. Sci. 2025; 22(11): 2583-2593. doi:10.7150/ijms.109069
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Deciphering the Relationship Between Circulating Metabolites and Osteoarthritis: A Comprehensive Genetic Correlation and Mendelian Randomization Studies Guang Yang, Wenqing Xie, Hengzhen Li, Wenhao Lu, Ying Liang, Yusheng Li, Yaping Wang, Wenfeng Xiao
Int. J. Med. Sci. 2025; 22(11): 2609-2619. doi:10.7150/ijms.111848
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Notable influences of estrogen and sex-specific microenvironment in colorectal cancer revealed by single-cell transcriptome analysis Yihui Zheng, Chaoxin Yang, Guozhong Xiao, Mingyuan Lei, Pengfei Qin, Huaxian Chen, Hongcheng Lin
Int. J. Med. Sci. 2025; 22(11): 2637-2652. doi:10.7150/ijms.106133
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Neutrophil Percentage-to-Albumin Ratio as a Prognostic Marker for Mortality in Ischemic Stroke Patients Yue-xin Lu, Bao-jie Mao, Ming Wang, Shu Wan
Int. J. Med. Sci. 2025; 22(11): 2663-2675. doi:10.7150/ijms.108493
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Establish VO2max prediction models based on exercise and body parameters from the step test Chia-An Ho, Hung-Chih Yeh, Hei-Tung Lau, En-Yu Chang, Chih-Wen Hsu, Chun-Hao Chang, Chi-Chang Huang, Wen-Sheng Chang Chien, Chin-Shan Ho
Int. J. Med. Sci. 2025; 22(11): 2676-2685. doi:10.7150/ijms.109977
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The screening assessment of pro-inflammatory, anti-inflammatory, Th1, Th2 and Th17 cytokines in saliva of patients with ischemic stroke Dominika Forszt, Karolina Gerreth, Jakub Kopczyński, Anna Zalewska, Katarzyna Hojan, Renata Marchewka, Marzena Bielas, Mateusz Maciejczyk
Int. J. Med. Sci. 2025; 22(11): 2686-2699. doi:10.7150/ijms.110452
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ABCG1 promotes the proliferation and migration of clear cell renal cell carcinoma and reduces its apoptosis Yihan Dong, Qiufang Qiao, Shaomin Guo, Ruibing Chen, Tianyu Lin, Xinyu Liu, Jiaxin Li, Shiming Liu, Huamao Jiang, Yong Wang, Dan Yue, Rui Wang
Int. J. Med. Sci. 2025; 22(11): 2721-2737. doi:10.7150/ijms.107055
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Diagnostic Value of the Detection of Microbiota, Multiple Inflammation-Related Indicators, Serum Lipid Indices, and Tumour Markers in Colorectal Polyps: A Case-Control Study Limin Zhang, Guoxiu Xiao, Duyao Su, Xun Wang, Cuiting Lv, Chunchun Li, Mingsheng Fu, Liang Song
Int. J. Med. Sci. 2025; 22(11): 2757-2770. doi:10.7150/ijms.108819
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Associations Between Long-Term Exposure to Air Pollutants and Prostate Cancer in a Large Taiwanese Population Jiun-Hung Geng, Chia-Yang Li, Ming-Tsang Wu, Szu-Chia Chen, Shu-Pin Huang
Int. J. Med. Sci. 2025; 22(11): 2771-2781. doi:10.7150/ijms.109687
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Development Of the VAMPCT Score for Predicting Mortality in CKD Patients with COVID-19 Chaofan Li, Yue Niu, Xinyan Pan, Dinghua Chen, Fei Liu, Zhe Feng, Yong Wang, Xueying Cao, Jie Wu, Jiabao Liu, Xin Guan, Xuefeng Sun, Li Zhang, Guangyan Cai, Xiangmei Chen, Ping Li
Int. J. Med. Sci. 2025; 22(11): 2782-2791. doi:10.7150/ijms.111558
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Efficacy of Acupuncture in Managing Radiation-Induced Xerostomia: An Updated Meta-Analysis Ru-Yin Tsai, Sheng-Yi Lin, Chin-Chang Chen, Yao Hsiao
Int. J. Med. Sci. 2025; 22(11): 2802-2815. doi:10.7150/ijms.110366
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PDGF-BB/EGR1 Axis Drives Fibroblast Activation Protein Expression to Promote Abdominal Aortic Aneurysm Zhihao Zhou, Lin Huang, Hui Luo, Rongzhou He, Ridong Wu, Rui Wang, Kangjie Wang, Chen Yao
Int. J. Med. Sci. 2025; 22(11): 2816-2829. doi:10.7150/ijms.114429
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Association of cardiorespiratory fitness with adverse outcomes in patients with and without atrial fibrillation: a prospective cohort study Yutong Wang, Tao Xu, Chenxi Xia, Xinyang Song, Yanwen Chen, Sixian Weng, Fang Wang
Int. J. Med. Sci. 2025; 22(11): 2830-2838. doi:10.7150/ijms.110802
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Screening and Evaluation of tRF-Glu-CTC-013 as a Biomarker and Key Regulator in the Development of Cardiac Hypertrophy Wenlin Li, Ming Lan, Kun Xu, Sainan Li, Que Wang, Beidong Chen, Xiuqing Huang, Lin Dou, Na Jia, Li Zhao, Yuefeng Wang, Xingyun Jiao, Yong Man, Deping Liu, Liang Sun, Tong Zou, Qing He, Jian Li, Xue Yu, Tao Shen
Int. J. Med. Sci. 2025; 22(11): 2839-2851. doi:10.7150/ijms.106114
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Reviews
Unraveling the Role of N6-Methylation Modification: From Bone Biology to Osteoporosis Junyi Liu, Xiang Chen, Xijie Yu
Int. J. Med. Sci. 2025; 22(11): 2545-2559. doi:10.7150/ijms.108763
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The interaction network between intestinal flora and cell death in microecosystem of pan-cancers Yuhan Zhang, Cenzhu Wang, Tingyan Ruan, Shuai Liang, Huning Jiang, Xi Wu, Rui Hou, Hanfang Fan, Huiyu Wang, Junli Ding, Junying Xu
Int. J. Med. Sci. 2025; 22(11): 2596-2608. doi:10.7150/ijms.111723
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The Autonomic Nervous System in Acupuncture for Gastrointestinal Dysmotility: From Anatomical Insights to Clinical Medicine Na-Na Yang, Xiao-Xia Xie, Wen-Li Yan, Yi-Duo Liu, He-Xuan Wang, Liu-Xin Yang, Cun-Zhi Liu
Int. J. Med. Sci. 2025; 22(11): 2620-2636. doi:10.7150/ijms.107643
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Efficacy of Laser Therapy for Grade C Periodontitis in Young Individuals Sijia Liu, Wanqing Zhao, Yusen Qie, Na Liu, Qing Liu
Int. J. Med. Sci. 2025; 22(11): 2653-2662. doi:10.7150/ijms.107543
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A Bibliometric Analysis of Neuroinflammation in Depression from 2004 to 2023: Global Research Hotspots and Prospects Anni Shi, Na Chen, Qin Ma, Yaxuan Wang, Xiaoling Liu, Jun Lu, Jianyou Guo
Int. J. Med. Sci. 2025; 22(11): 2700-2720. doi:10.7150/ijms.100888
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Expert Consensus on the Diagnosis and Management of Carotid Atherosclerotic Plaque: Pathophysiology, Clinical Management, and Preventive Approaches Xing Chang, Hang Zhu, Zhijiang Guo, Hongshuo Shi, Yingjie Tian, Qianying Hao, Hui Zhang, Rongjun Zou, Xiaoping Fan, Qihui Zhang, Sang-Bing Ong, Qingyong He, Hao Zhou
Int. J. Med. Sci. 2025; 22(11): 2738-2756. doi:10.7150/ijms.107479
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Large Language Models in Medicine: Applications, Challenges, and Future Directions Erlan Yu, Xuehong Chu, Wanwan Zhang, Xiangbin Meng, Yaodong Yang, Xunming Ji, Chuanjie Wu
Int. J. Med. Sci. 2025; 22(11): 2792-2801. doi:10.7150/ijms.111780
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Fructose Metabolism in Cancer: Molecular Mechanisms and Therapeutic Implications Xinyi Chen, Mu Yang, Lu Wang, Jingyao Tu, Xianglin Yuan
Int. J. Med. Sci. 2025; 22(11): 2852-2876. doi:10.7150/ijms.108549
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Erratum
Lentivirus-mediated shRNA Targeting CNN2 Inhibits Hepatocarcinoma in Vitro and in Vivo: Erratum Xueqing Kang, Feng Wang, Xiuwan Lan, Xiaolong Li, Shunxin Zheng, Zhilue Lv, Yuan Zhuang, Yongxiang Zhao, Sufang Zhou
Int. J. Med. Sci. 2025; 22(11): 2594-2595. doi:10.7150/ijms.114964
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