Impact Factor ISSN: 1449-1907
Research Paper DPP-4 Inhibition Differentially Reprograms Inflammatory and Nociceptive Responses in Human Osteoarthritic Chondrocytes and Synovial Fibroblasts Full text PDF
Research Paper The influence of significant cycloplegia astigmatism deviation on the outcome of second-generation (VisuMax 800) keratorefractive lenticule extraction surgery Full text PDF
Review The Dual Role of Hypoxia-Inducible Factors in Oral and Maxillofacial Bone: From Pathological Destruction to Regenerative Potential Full text PDF
Research Paper A WHO-Grade-Derived Meningioma Transcriptomic Program: Cross-Cohort Recurrence Association and Single-Cell Contextualization Full text PDF
Research Paper Transcriptomic Alterations in Peri-Implantitis Tissues from Patients with Diabetes, Hypertension, and Osteoporosis: An Exploratory Candidate-Gene Study Full text PDF
Review The MQC-Metal-PANoptosis Axis in Sepsis: A Two-Hit Model of Immune Exhaustion Full text PDF
Issue 10; 2026
Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
Full texts of articles appear in PubMed Central and Europe PMC.
The MQC-Metal-PANoptosis Axis in Sepsis: A Two-Hit Model of Immune Exhaustion
Sepsis has undergone a paradigm shift from isolated cytokine-driven models to integrated cellular fate decisions. A key clinical hallmark is the transition from early hyperinflammation to late immunosuppression, which is fundamentally linked to the functional exhaustion and massive depletion of CD4⁺ T cells. Here, we propose a testable two-hit model for sepsis-induced CD4⁺ T cell death and immune failure. In this model, the combined failure ...
Journal of Genomics recent articles:
Research Paper Whole-Genome sequencing and phylogenomic analyses of Alternaria japonica and A. telliensis (Section Japonicae) Full text PDF PubMed PMC