Impact Factor ISSN: 1449-1907
Review The MQC-Metal-PANoptosis Axis in Sepsis: A Two-Hit Model of Immune Exhaustion Full text PDF
Review Non-Biological Liver Support Systems for Hepatic Encephalopathy: A Framework for Phenotype-Matched Precision Management Full text PDF
Research Paper Muscle-Related Parameters and Sarcopenia According to Hearing-Loss Severity and Hearing-Aid Use Full text PDF
Research Paper Percutaneous Nephrolithotomy in a Hybrid Operating Room: Clinical Outcomes, Intraoperative Cone-Beam CT Use, and Early Learning Curve from a Single-Center Experience Full text PDF
Research Paper Epigenome-Wide DNA Methylation Profiling of Matched Primary Breast Cancers and Brain Metastases Reveals Epigenetic Markers linked to Metastatic Progression: A Preliminary Study Full text PDF
Research Paper Short-Term Changes in Segmental Multi-Frequency Bioelectrical Impedance Measurements Following Water and Banana Intake: A Fixed-Order Within-Subject Study Full text PDF
Issue 10; 2026
Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
Full texts of articles appear in PubMed Central and Europe PMC.
The MQC-Metal-PANoptosis Axis in Sepsis: A Two-Hit Model of Immune Exhaustion
Sepsis has undergone a paradigm shift from isolated cytokine-driven models to integrated cellular fate decisions. A key clinical hallmark is the transition from early hyperinflammation to late immunosuppression, which is fundamentally linked to the functional exhaustion and massive depletion of CD4⁺ T cells. Here, we propose a testable two-hit model for sepsis-induced CD4⁺ T cell death and immune failure. In this model, the combined failure ...
Journal of Genomics recent articles:
Research Paper Whole-Genome sequencing and phylogenomic analyses of Alternaria japonica and A. telliensis (Section Japonicae) Full text PDF