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Review
The role and mechanisms of Microglia in Neuromyelitis Optica Spectrum Disorders
Wenqun Li, Jiaqin Liu, Wei Tan, Yedi Zhou
Int. J. Med. Sci. 2021; 18(14): 3059-3065. doi:10.7150/ijms.61153
[Abstract] [Full text] [PDF]


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Research Paper
Altered intestinal microflora and barrier injury in severe acute pancreatitis can be changed by zinc
Shi-yue Su, Qin-qing Tang
Int. J. Med. Sci. 2021; 18(14): 3050-3058. doi:10.7150/ijms.45980
[Abstract] [Full text] [PDF]


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Research Paper
Antitumor Activity of Small Activating RNAs Induced PAWR Gene Activation in Human Bladder Cancer Cells
Kai Yang, Jie Shen, Fu-Qing Tan, Xiang-Yi Zheng, Li-Ping Xie
Int. J. Med. Sci. 2021; 18(13): 3039-3049. doi:10.7150/ijms.60399
[Abstract] [Full text] [PDF]


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Research Paper
The underlying molecular mechanism and drugs for treatment in adrenal cortical carcinoma
Chengquan Ma, Jian Xiong, Hao Su, Hongjun Li
Int. J. Med. Sci. 2021; 18(13): 3026-3038. doi:10.7150/ijms.60261
[Abstract] [Full text] [PDF]


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Research Paper
Experimental postoperative ileus: is Th2 immune response involved?
Sisi Lin, Florian Kühn, Tobias S. Schiergens, Andrey A. Zamyatnin, Orkhan Isayev, Eldar Gasimov, Jens Werner, Yongyu Li, Alexandr V. Bazhin
Int. J. Med. Sci. 2021; 18(13): 3014-3025. doi:10.7150/ijms.59354
[Abstract] [Full text] [PDF]


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Research Paper
CD8+ T cell survival in lethal fungal sepsis was ameliorated by T-cell-specific mTOR deletion
Hao Wang, Wen Han, Ran Guo, Guangxu Bai, Jianwei Chen, Na Cui
Int. J. Med. Sci. 2021; 18(13): 3004-3013. doi:10.7150/ijms.55592
[Abstract] [Full text] [PDF]


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Research Paper
TRIM21 Polymorphisms are associated with Susceptibility and Clinical Status of Oral Squamous Cell Carcinoma patients
Chun-Yi Chuang, Yi-Chung Chien, Chiao-Wen Lin, Chia-Hsuan Chou, Shuo-Chueh Chen, Chun-Lin Liu, Li-Yuan Bai, Shun-Fa Yang, Yung-Luen Yu
Int. J. Med. Sci. 2021; 18(13): 2997-3003. doi:10.7150/ijms.56614
[Abstract] [Full text] [PDF]


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Research Paper
Determination of Bioelectrical Impedance Thresholds for Early Detection of Breast Cancer-related Lymphedema
Siyao Liu, Quanping Zhao, Xinmei Ren, Ying Cui, Houpu Yang, Siyuan Wang, Miao Liu, Shu Wang
Int. J. Med. Sci. 2021; 18(13): 2990-2996. doi:10.7150/ijms.53812
[Abstract] [Full text] [PDF]


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Research Paper
Salmonella alters heparanase expression and reduces tumor metastasis
Huan-Min Chiu, Wen- Yi Chiou, Wei-Jie Hsu, Li-Hsien Wu, Ming-Hui Yang, Yu-Chang Tyan, Che-Hsin Lee
Int. J. Med. Sci. 2021; 18(13): 2981-2989. doi:10.7150/ijms.60281
[Abstract] [Full text] [PDF]


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Research Paper
Efficacy of bisphosphonates in detection of early enamel caries using NIR fluorescence imaging and inhibition of caries progression
Jie Sun, Mindy Gil, Shahrzad Khorashadi, George Chen, Cliff Lee, Yoshiki Ishida, Masazumi Nagai, Shinichiro Wada, Shigemi Ishikawa-Nagai, John D Da Silva
Int. J. Med. Sci. 2021; 18(13): 2971-2980. doi:10.7150/ijms.60013
[Abstract] [Full text] [PDF]


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Research Paper
Lower serum bilirubin is associated with poor renal outcome in IgA nephropathy patients
Zheng Jiang, Jiaxing Tan, Siqing Wang, Lingqiu Dong, Xin Han, Yi Tang, Wei Qin
Int. J. Med. Sci. 2021; 18(13): 2964-2970. doi:10.7150/ijms.60111
[Abstract] [Full text] [PDF]


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Research Paper
Factors associated with Successful Responses to Ganglion Impar Block: A Retrospective Study
Chan-Sik Kim, Kyounghwan Jang, Jeong-Gil Leem, Jin-Woo Shin, Doo-Hwan Kim, Seong-Soo Choi
Int. J. Med. Sci. 2021; 18(13): 2957-2963. doi:10.7150/ijms.60962
[Abstract] [Full text] [PDF]


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Research Paper
Distinct Patterns of Brain Atrophy associated with Mild Behavioral Impairment in Cognitively Normal Elderly Adults
Jun Shu, Qiang Qiang, Yuning Yan, Yang Wen, Yiqing Ren, Wenshi Wei, Li Zhang
Int. J. Med. Sci. 2021; 18(13): 2950-2956. doi:10.7150/ijms.60810
[Abstract] [Full text] [PDF]


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Review
Designing Nanoparticle-based Drug Delivery Systems for Precision Medicine
Jianhua Yang, Chengyou Jia, Jianshe Yang
Int. J. Med. Sci. 2021; 18(13): 2943-2949. doi:10.7150/ijms.60874
[Abstract] [Full text] [PDF]


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Research Paper
Enhancement of cytotoxicity and induction of apoptosis by cationic nano-liposome formulation of n-butylidenephthalide in breast cancer cells
Xiao-Fan Huang, Kai-Fu Chang, Yu-Ling Lin, Kuang-Wen Liao, Chih-Yen Hsiao, Gwo-Tarng Sheu, Nu-Man Tsai
Int. J. Med. Sci. 2021; 18(13): 2930-2942. doi:10.7150/ijms.51439
[Abstract] [Full text] [PDF]


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Research Paper
Selective brain cooling achieves peripheral organs protection in hemorrhagic shock resuscitation via preserving the integrity of the brain-gut axis
Chien-Ming Chao, Chien-Chin Hsu, Chien-Cheng Huang, Chung-Han Wang, Mao-Tsun Lin, Ching-Ping Chang, Hung-Jung Lin, Chung-Ching Chio
Int. J. Med. Sci. 2021; 18(13): 2920-2929. doi:10.7150/ijms.61191
[Abstract] [Full text] [PDF]

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Full texts of articles appear in PubMed Central and Europe PMC.

Journal of Genomics recent articles:

Research Paper
Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity
Tawanda Elias Maguvu, Adegboyega Oyedele Oladipo, Cornelius Carlos Bezuidenhout
J. Genomics 2021; 9: 26-37. doi:10.7150/jgen.53019
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Draft genome sequences of three filamentous cyanobacteria isolated from brackish habitats
Joanne Sarah Boden, Michele Grego, Henk Bolhuis, Patricia Sánchez-Baracaldo
J. Genomics 2021; 9: 20-25. doi:10.7150/jgen.53678
[Abstract] [Full text] [PDF] [PubMed] [PMC]


Review
The Genetic Background of Central Serous Chorioretinopathy: A Review on Central Serous Chorioretinopathy Genes
Konstantinos Giannopoulos, Maria Gazouli, Klio Chatzistefanou, Anthi Bakouli, Marilita M Moschos
J. Genomics 2021; 9: 10-19. doi:10.7150/jgen.55545
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Top cited papers:

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

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