Front cover

◂ Last issue Next issue ▸ Archive Cover PDF   

Volume 22 (14); 2025

Research Papers

Graphic abstract

C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway Luen-Kui Chen, Chien-Wei Chen, Shao-Yun Wu, Shui-Yu Liu, Liang-Yi Wu, Chi-Jen Chang, Leticia B. Sy, Chi-Chang Juan Int. J. Med. Sci. 2025; 22(14): 3490-3500. doi:10.7150/ijms.115524 Full text PDF PubMed PMC

Graphic abstract

Establishment of a Stacking Machine Learning Model Predicting Cardiac Phenotype in Ectopia Lentis Patients Based on Genotype and Ocular Phenotype Linghao Song, Ao Miao, Xinyue Wang, Yan Liu, Xin Shen, Zexu Chen, Wannan Jia, Yalei Wang, Xinyao Chen, Tianhui Chen, Yongxiang Jiang Int. J. Med. Sci. 2025; 22(14): 3501-3510. doi:10.7150/ijms.109657 Full text PDF PubMed PMC

Graphic abstract

Vascular Endothelial Protection Effects of Curcuma wenyujin Root Aqueous Extracts on LPS-induced Rat Vascular Damage Li-Hsien Chen, Sheau-Chung Tang, Shu-Er Yang, Erl-Shyh Kao Int. J. Med. Sci. 2025; 22(14): 3556-3564. doi:10.7150/ijms.112103 Full text PDF PubMed PMC

Graphic abstract

Causal Effects of Exposure to Air Pollution on the Risk of Neurosurgical Multi-system Diseases: A Worldwide Study of Mendelian Randomization Lirui Dai, Shu Jiang, Peizhi Zhou Int. J. Med. Sci. 2025; 22(14): 3565-3580. doi:10.7150/ijms.115853 Full text PDF PubMed PMC

Graphic abstract

Nomogram for Predicting Postoperative Blood Pressure Reduction in Hypertensive Patients: A Single-Center Retrospective Study Zongsu Zhang, Xiaocheng Ma, Zhaochen Li, Haotian Wei, Kaipeng Jia, Chenglong Xu, Shimiao Zhu, Simeng Wen, Changyi Quan Int. J. Med. Sci. 2025; 22(14): 3581-3590. doi:10.7150/ijms.112777 Full text PDF PubMed PMC

Graphic abstract

The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment Chia-Yi Lee, Shun-Fa Yang, Jing-Yang Huang, Chao-Kai Chang Int. J. Med. Sci. 2025; 22(14): 3591-3597. doi:10.7150/ijms.113380 Full text PDF PubMed PMC

Graphic abstract

miR-6126 modulates GRP78 to suppress the Warburg effect and mitochondrial dynamics in triple-negative breast cancer Wei-Jan Wang, Jian-Sheng Liu, Nguyen Hoang Anh Kha, Wan-Jou Shen, Chih-Jung Chen, Shuan-Chu Chen, Pin-Chen Liao, Chih-Yang Huang, Wei-Wen Kuo Int. J. Med. Sci. 2025; 22(14): 3598-3616. doi:10.7150/ijms.107240 Full text PDF PubMed PMC

Graphic abstract

Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study Aysenur Genc, Betul Gedik, Mehmet Ali Erdem, Abdulkadir Burak Cankaya Int. J. Med. Sci. 2025; 22(14): 3617-3624. doi:10.7150/ijms.113282 Full text PDF PubMed PMC

Graphic abstract

miR-548aj-3p and miR-3127-3p suppress RANKL-facilitated inflammatory cytokines and catabolic factor in osteoarthritis and rheumatoid arthritis Yu-Han Wang, Chin-Horng Su, Li-Chai Chen, Ju-Fang Liu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Lun-Chien Lo, Chih-Hsin Tang Int. J. Med. Sci. 2025; 22(14): 3650-3663. doi:10.7150/ijms.110812 Full text PDF PubMed PMC

Graphic abstract

Temporal Effects of Lipid Oversupply on Energy Metabolism and Mitochondrial Homeostasis in Hepatocytes Cheng-Chieh Chuang, Ying-Hao Chen, Fang-Yeh Chu, Ching-Ping Yang, Hsiang-Ling Ho, Fu-Pang Chang, Yu-Li Lo, Chun-Jung Chen, Yih-Hsin Chang Int. J. Med. Sci. 2025; 22(14): 3664-3681. doi:10.7150/ijms.104128 Full text PDF PubMed PMC

Graphic abstract

Galangin Mitigates Oxidative Damage Induced by Environmental Stresses in Skin Keratinocytes Herath Mudiyanselage Udari Lakmini Herath, Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Maheshika Madhuwanthi Senavirathna, Young Sang Koh, Eui Tae Kim, Suk Ju Cho, Jin Won Hyun Int. J. Med. Sci. 2025; 22(14): 3682-3691. doi:10.7150/ijms.112872 Full text PDF PubMed PMC

Graphic abstract

The probiotic Lactobacillus kefiranofaciens K6 alleviates exercise and sleep deprivation-induced physiological dysregulation and neuropsychiatric disorders via modulation of inflammation, circadian rhythm, and stress response Chien-Wei Chen, Li-Ting Wu, Po-Hao Chiu, Yen-Po Chen, Wen-Ching Huang Int. J. Med. Sci. 2025; 22(14): 3722-3736. doi:10.7150/ijms.115387 Full text PDF PubMed PMC

Graphic abstract

FAM174B remodels the tumor microenvironment, inhibits the infiltration of macrophage, predicts the molecular subtype and therapeutic response of bladder cancer Hualin Chen, Lin Ma, Zhigang Ji, Jie Dong Int. J. Med. Sci. 2025; 22(14): 3737-3748. doi:10.7150/ijms.110096 Full text PDF PubMed PMC

Graphic abstract

A Machine Learning-Based Hypoxia-Related Gene Signatures to Facilitate Prediction of Cetuximab Response in Patients with Colorectal Cancer Cuizhen Zhang, Wanjie Niu, Jiangtao Zhang, Yingyi Zheng, Zhiru Chen, Fali Zhang, Xiaoyan Qiu Int. J. Med. Sci. 2025; 22(14): 3749-3762. doi:10.7150/ijms.114833 Full text PDF PubMed PMC

Graphic abstract

Dual-Function RNA Biomarkers: Integrating Relapse Prediction and Immune Profiling in Triple-Negative Breast Cancer Ying Wen, Yuanyuan Tang, Qiongyan Zou Int. J. Med. Sci. 2025; 22(14): 3763-3778. doi:10.7150/ijms.119142 Full text PDF PubMed PMC

Graphic abstract

Role of Estimated Glucose Disposal Rate in Staging and Death Risk of Cardiovascular-Kidney-Metabolic Syndrome: Insights from NHANES 1999-2018 Jin Ke, Shuang Wu, Hongyang Xu, Fengming Liang, Jing Tian, Qiuhui Wang, Yang Chen Int. J. Med. Sci. 2025; 22(14): 3779-3788. doi:10.7150/ijms.116708 Full text PDF PubMed PMC

Graphic abstract

Development and validation of a prediction model for recurrence based on ProMisE molecular classifier and immune-inflammatory- nutritional score in endometrial carcinoma: a retrospective multiple-center study Yunfeng Zheng, Fan Yang, Gaohua Liu, Xixi Wu, Langting Xie, Ran Hu, Xiaoxiao Luo, Rui Yuan Int. J. Med. Sci. 2025; 22(14): 3789-3801. doi:10.7150/ijms.107134 Full text PDF PubMed PMC

Graphic abstract

Protective Effects of Kelulut Honey on Bone Strength and Marrow Adiposity in Rats Fed with High-Carbohydrate High-Fat Diet Sophia Ogechi Ekeuku, Khairun-Nisa Hashim, Jen Kit Tan, Michelle Yee Min Fang, Nur Zuliani Ramli, Khairul Anwar Zarkasi, Kok-Yong Chin, Fairus Ahmad Int. J. Med. Sci. 2025; 22(14): 3802-3814. doi:10.7150/ijms.115978 Full text PDF PubMed PMC

Reviews

Graphic abstract

Association Between Gut Microbiota and Pneumonia Risk: A Systematic Review and Mendelian Randomization Qingping Deng, Yuanyuan Liu, Hui Rong, Qing Liu, Rongyuan Yang Int. J. Med. Sci. 2025; 22(14): 3511-3527. doi:10.7150/ijms.114372 Full text PDF PubMed PMC

Graphic abstract

Metabolism and Targeted Therapy of Fibrosis in Chronic Pancreatitis: A Review Hongqing Luo, Shan Guo, Yuning Chu, Yiping Xin, Xiaoyan Yin, Xiaoyu Li Int. J. Med. Sci. 2025; 22(14): 3528-3542. doi:10.7150/ijms.118338 Full text PDF PubMed PMC

Graphic abstract

Role of Metabolic Abnormalities During the Progression of Chronic Kidney Disease and Preventive Strategies Dongqing Zha, Ping Gao, Xiaoyan Wu Int. J. Med. Sci. 2025; 22(14): 3543-3555. doi:10.7150/ijms.114382 Full text PDF PubMed PMC

Graphic abstract

Overcoming the Delivery Challenges in CRISPR/Cas9 Gene Editing for Effective Cancer Treatment: A Review of Delivery Systems Shuting Tang, Xiaoyi Chen, Xiangmin Tong, Lifen Zhu Int. J. Med. Sci. 2025; 22(14): 3625-3649. doi:10.7150/ijms.112724 Full text PDF PubMed PMC

Graphic abstract

Mesenchymal Stem Cells Senescence: Mechanism and Rejuvenation Interventions Qinghong Meng, Yan Zheng, Xiaobo Chen, Jiawei Mu, Changlin Li, Yiwen Gao, Wei Liu, Yuliang Wang Int. J. Med. Sci. 2025; 22(14): 3692-3708. doi:10.7150/ijms.115650 Full text PDF PubMed PMC

Graphic abstract

Health-Related Quality of Life in Patients with Hepatocellular Carcinoma Post-Surgery: A Scoping Review Wei-Zheng Zhang, Kok-Yong Chin, Roshaya Zakaria, Nor Haty Hassan Int. J. Med. Sci. 2025; 22(14): 3709-3721. doi:10.7150/ijms.115946 Full text PDF PubMed PMC

Popup Image

©2026 Ivyspring International Publisher. All rights reserved.
Open access content is subject to applicable licences. By accessing or using this platform, you agree to our Terms of Use.