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Volume 22 (14); 2025

Research Papers

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Extracellular Matrix Stiffness Enhancement Promotes Docetaxel Resistance in Prostate Cancer via Inhibition of Apoptosis Mediated by Upregulation of PRRX1
Jiahao Chen, Mengting Chen, Zhiwen Xie, Luheng Shen, Juntao Jiang, Shujie Xia
Int. J. Med. Sci. 2025; 22(14): 3454-3463. doi:10.7150/ijms.111171
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Total Bile Acids: A Game-Changer in Predicting Short-Term Outcomes in AIS Patients Undergoing Thrombolysis
Zhuohang Liu, Min Chu, Zengyu Zhang, Jing Zhao
Int. J. Med. Sci. 2025; 22(14): 3464-3476. doi:10.7150/ijms.108310
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NDUFS1 upregulates ENaCα by NAD+ to promote alveolar fluid clearance in acute lung injury
Mengmeng Wang, Mengting Chen, Jianping Zhu, Yu Zhang, Jian Lu, Zhiying Yue, Zhengfeng Yang, Ruilan Wang
Int. J. Med. Sci. 2025; 22(14): 3477-3489. doi:10.7150/ijms.112248
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C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway
Luen-Kui Chen, Chien-Wei Chen, Shao-Yun Wu, Shui-Yu Liu, Liang-Yi Wu, Chi-Jen Chang, Leticia B. Sy, Chi-Chang Juan
Int. J. Med. Sci. 2025; 22(14): 3490-3500. doi:10.7150/ijms.115524
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Establishment of a Stacking Machine Learning Model Predicting Cardiac Phenotype in Ectopia Lentis Patients Based on Genotype and Ocular Phenotype
Linghao Song, Ao Miao, Xinyue Wang, Yan Liu, Xin Shen, Zexu Chen, Wannan Jia, Yalei Wang, Xinyao Chen, Tianhui Chen, Yongxiang Jiang
Int. J. Med. Sci. 2025; 22(14): 3501-3510. doi:10.7150/ijms.109657
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Vascular Endothelial Protection Effects of Curcuma wenyujin Root Aqueous Extracts on LPS-induced Rat Vascular Damage
Li-Hsien Chen, Sheau-Chung Tang, Shu-Er Yang, Erl-Shyh Kao
Int. J. Med. Sci. 2025; 22(14): 3556-3564. doi:10.7150/ijms.112103
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Causal Effects of Exposure to Air Pollution on the Risk of Neurosurgical Multi-system Diseases: A Worldwide Study of Mendelian Randomization
Lirui Dai, Shu Jiang, Peizhi Zhou
Int. J. Med. Sci. 2025; 22(14): 3565-3580. doi:10.7150/ijms.115853
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Nomogram for Predicting Postoperative Blood Pressure Reduction in Hypertensive Patients: A Single-Center Retrospective Study
Zongsu Zhang, Xiaocheng Ma, Zhaochen Li, Haotian Wei, Kaipeng Jia, Chenglong Xu, Shimiao Zhu, Simeng Wen, Changyi Quan
Int. J. Med. Sci. 2025; 22(14): 3581-3590. doi:10.7150/ijms.112777
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The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment
Chia-Yi Lee, Shun-Fa Yang, Jing-Yang Huang, Chao-Kai Chang
Int. J. Med. Sci. 2025; 22(14): 3591-3597. doi:10.7150/ijms.113380
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miR-6126 modulates GRP78 to suppress the Warburg effect and mitochondrial dynamics in triple-negative breast cancer
Wei-Jan Wang, Jian-Sheng Liu, Nguyen Hoang Anh Kha, Wan-Jou Shen, Chih-Jung Chen, Shuan-Chu Chen, Pin-Chen Liao, Chih-Yang Huang, Wei-Wen Kuo
Int. J. Med. Sci. 2025; 22(14): 3598-3616. doi:10.7150/ijms.107240
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Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study
Aysenur Genc, Betul Gedik, Mehmet Ali Erdem, Abdulkadir Burak Cankaya
Int. J. Med. Sci. 2025; 22(14): 3617-3624. doi:10.7150/ijms.113282
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miR-548aj-3p and miR-3127-3p suppress RANKL-facilitated inflammatory cytokines and catabolic factor in osteoarthritis and rheumatoid arthritis
Yu-Han Wang, Chin-Horng Su, Li-Chai Chen, Ju-Fang Liu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Lun-Chien Lo, Chih-Hsin Tang
Int. J. Med. Sci. 2025; 22(14): 3650-3663. doi:10.7150/ijms.110812
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Temporal Effects of Lipid Oversupply on Energy Metabolism and Mitochondrial Homeostasis in Hepatocytes
Cheng-Chieh Chuang, Ying-Hao Chen, Fang-Yeh Chu, Ching-Ping Yang, Hsiang-Ling Ho, Fu-Pang Chang, Yu-Li Lo, Chun-Jung Chen, Yih-Hsin Chang
Int. J. Med. Sci. 2025; 22(14): 3664-3681. doi:10.7150/ijms.104128
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Galangin Mitigates Oxidative Damage Induced by Environmental Stresses in Skin Keratinocytes
Herath Mudiyanselage Udari Lakmini Herath, Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Maheshika Madhuwanthi Senavirathna, Young Sang Koh, Eui Tae Kim, Suk Ju Cho, Jin Won Hyun
Int. J. Med. Sci. 2025; 22(14): 3682-3691. doi:10.7150/ijms.112872
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Reviews

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Effect of Pituitary-Target Gland Axis on RAAS in the Context of COVID-19
Baofeng Wu, Ru Li, Qinhao Liu, Shuqing Jin, Hongxia Wei, Ming Xu, Yi Zhang, Yunfeng Liu
Int. J. Med. Sci. 2025; 22(14): 3439-3453. doi:10.7150/ijms.114924
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Association Between Gut Microbiota and Pneumonia Risk: A Systematic Review and Mendelian Randomization
Qingping Deng, Yuanyuan Liu, Hui Rong, Qing Liu, Rongyuan Yang
Int. J. Med. Sci. 2025; 22(14): 3511-3527. doi:10.7150/ijms.114372
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Metabolism and Targeted Therapy of Fibrosis in Chronic Pancreatitis: A Review
Hongqing Luo, Shan Guo, Yuning Chu, Yiping Xin, Xiaoyan Yin, Xiaoyu Li
Int. J. Med. Sci. 2025; 22(14): 3528-3542. doi:10.7150/ijms.118338
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Role of Metabolic Abnormalities During the Progression of Chronic Kidney Disease and Preventive Strategies
Dongqing Zha, Ping Gao, Xiaoyan Wu
Int. J. Med. Sci. 2025; 22(14): 3543-3555. doi:10.7150/ijms.114382
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Overcoming the Delivery Challenges in CRISPR/Cas9 Gene Editing for Effective Cancer Treatment: A Review of Delivery Systems
Shuting Tang, Xiaoyi Chen, Xiangmin Tong, Lifen Zhu
Int. J. Med. Sci. 2025; 22(14): 3625-3649. doi:10.7150/ijms.112724
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Mesenchymal Stem Cells Senescence: Mechanism and Rejuvenation Interventions
Qinghong Meng, Yan Zheng, Xiaobo Chen, Jiawei Mu, Changlin Li, Yiwen Gao, Wei Liu, Yuliang Wang
Int. J. Med. Sci. 2025; 22(14): 3692-3708. doi:10.7150/ijms.115650
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Health-Related Quality of Life in Patients with Hepatocellular Carcinoma Post-Surgery: A Scoping Review
Wei-Zheng Zhang, Kok-Yong Chin, Roshaya Zakaria, Nor Haty Hassan
Int. J. Med. Sci. 2025; 22(14): 3709-3721. doi:10.7150/ijms.115946
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