◂ Last issue Next issue ▸ Archive   

Volume 22 (14); 2025

Research Papers

Graphic abstract

C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway
Luen-Kui Chen, Chien-Wei Chen, Shao-Yun Wu, Shui-Yu Liu, Liang-Yi Wu, Chi-Jen Chang, Leticia B. Sy, Chi-Chang Juan
Int. J. Med. Sci. 2025; 22(14): 3490-3500. doi:10.7150/ijms.115524
Full text PDF

Graphic abstract

Establishment of a Stacking Machine Learning Model Predicting Cardiac Phenotype in Ectopia Lentis Patients Based on Genotype and Ocular Phenotype
Linghao Song, Ao Miao, Xinyue Wang, Yan Liu, Xin Shen, Zexu Chen, Wannan Jia, Yalei Wang, Xinyao Chen, Tianhui Chen, Yongxiang Jiang
Int. J. Med. Sci. 2025; 22(14): 3501-3510. doi:10.7150/ijms.109657
Full text PDF

Graphic abstract

Vascular Endothelial Protection Effects of Curcuma wenyujin Root Aqueous Extracts on LPS-induced Rat Vascular Damage
Li-Hsien Chen, Sheau-Chung Tang, Shu-Er Yang, Erl-Shyh Kao
Int. J. Med. Sci. 2025; 22(14): 3556-3564. doi:10.7150/ijms.112103
Full text PDF

Graphic abstract

Causal Effects of Exposure to Air Pollution on the Risk of Neurosurgical Multi-system Diseases: A Worldwide Study of Mendelian Randomization
Lirui Dai, Shu Jiang, Peizhi Zhou
Int. J. Med. Sci. 2025; 22(14): 3565-3580. doi:10.7150/ijms.115853
Full text PDF

Graphic abstract

Nomogram for Predicting Postoperative Blood Pressure Reduction in Hypertensive Patients: A Single-Center Retrospective Study
Zongsu Zhang, Xiaocheng Ma, Zhaochen Li, Haotian Wei, Kaipeng Jia, Chenglong Xu, Shimiao Zhu, Simeng Wen, Changyi Quan
Int. J. Med. Sci. 2025; 22(14): 3581-3590. doi:10.7150/ijms.112777
Full text PDF

Graphic abstract

The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment
Chia-Yi Lee, Shun-Fa Yang, Jing-Yang Huang, Chao-Kai Chang
Int. J. Med. Sci. 2025; 22(14): 3591-3597. doi:10.7150/ijms.113380
Full text PDF

Graphic abstract

miR-6126 modulates GRP78 to suppress the Warburg effect and mitochondrial dynamics in triple-negative breast cancer
Wei-Jan Wang, Jian-Sheng Liu, Nguyen Hoang Anh Kha, Wan-Jou Shen, Chih-Jung Chen, Shuan-Chu Chen, Pin-Chen Liao, Chih-Yang Huang, Wei-Wen Kuo
Int. J. Med. Sci. 2025; 22(14): 3598-3616. doi:10.7150/ijms.107240
Full text PDF

Graphic abstract

Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study
Aysenur Genc, Betul Gedik, Mehmet Ali Erdem, Abdulkadir Burak Cankaya
Int. J. Med. Sci. 2025; 22(14): 3617-3624. doi:10.7150/ijms.113282
Full text PDF

Graphic abstract

miR-548aj-3p and miR-3127-3p suppress RANKL-facilitated inflammatory cytokines and catabolic factor in osteoarthritis and rheumatoid arthritis
Yu-Han Wang, Chin-Horng Su, Li-Chai Chen, Ju-Fang Liu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Lun-Chien Lo, Chih-Hsin Tang
Int. J. Med. Sci. 2025; 22(14): 3650-3663. doi:10.7150/ijms.110812
Full text PDF

Graphic abstract

Temporal Effects of Lipid Oversupply on Energy Metabolism and Mitochondrial Homeostasis in Hepatocytes
Cheng-Chieh Chuang, Ying-Hao Chen, Fang-Yeh Chu, Ching-Ping Yang, Hsiang-Ling Ho, Fu-Pang Chang, Yu-Li Lo, Chun-Jung Chen, Yih-Hsin Chang
Int. J. Med. Sci. 2025; 22(14): 3664-3681. doi:10.7150/ijms.104128
Full text PDF

Graphic abstract

Galangin Mitigates Oxidative Damage Induced by Environmental Stresses in Skin Keratinocytes
Herath Mudiyanselage Udari Lakmini Herath, Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Maheshika Madhuwanthi Senavirathna, Young Sang Koh, Eui Tae Kim, Suk Ju Cho, Jin Won Hyun
Int. J. Med. Sci. 2025; 22(14): 3682-3691. doi:10.7150/ijms.112872
Full text PDF

Graphic abstract

The probiotic Lactobacillus kefiranofaciens K6 alleviates exercise and sleep deprivation-induced physiological dysregulation and neuropsychiatric disorders via modulation of inflammation, circadian rhythm, and stress response
Chien-Wei Chen, Li-Ting Wu, Po-Hao Chiu, Yen-Po Chen, Wen-Ching Huang
Int. J. Med. Sci. 2025; 22(14): 3722-3736. doi:10.7150/ijms.115387
Full text PDF

Graphic abstract

FAM174B remodels the tumor microenvironment, inhibits the infiltration of macrophage, predicts the molecular subtype and therapeutic response of bladder cancer
Hualin Chen, Lin Ma, Zhigang Ji, Jie Dong
Int. J. Med. Sci. 2025; 22(14): 3737-3748. doi:10.7150/ijms.110096
Full text PDF

Graphic abstract

A Machine Learning-Based Hypoxia-Related Gene Signatures to Facilitate Prediction of Cetuximab Response in Patients with Colorectal Cancer
Cuizhen Zhang, Wanjie Niu, Jiangtao Zhang, Yingyi Zheng, Zhiru Chen, Fali Zhang, Xiaoyan Qiu
Int. J. Med. Sci. 2025; 22(14): 3749-3762. doi:10.7150/ijms.114833
Full text PDF

Graphic abstract

Dual-Function RNA Biomarkers: Integrating Relapse Prediction and Immune Profiling in Triple-Negative Breast Cancer
Ying Wen, Yuanyuan Tang, Qiongyan Zou
Int. J. Med. Sci. 2025; 22(14): 3763-3778. doi:10.7150/ijms.119142
Full text PDF

Graphic abstract

Role of Estimated Glucose Disposal Rate in Staging and Death Risk of Cardiovascular-Kidney-Metabolic Syndrome: Insights from NHANES 1999-2018
Jin Ke, Shuang Wu, Hongyang Xu, Fengming Liang, Jing Tian, Qiuhui Wang, Yang Chen
Int. J. Med. Sci. 2025; 22(14): 3779-3788. doi:10.7150/ijms.116708
Full text PDF

Graphic abstract

Development and validation of a prediction model for recurrence based on ProMisE molecular classifier and immune-inflammatory- nutritional score in endometrial carcinoma: a retrospective multiple-center study
Yunfeng Zheng, Fan Yang, Gaohua Liu, Xixi Wu, Langting Xie, Ran Hu, Xiaoxiao Luo, Rui Yuan
Int. J. Med. Sci. 2025; 22(14): 3789-3801. doi:10.7150/ijms.107134
Full text PDF

Graphic abstract

Protective Effects of Kelulut Honey on Bone Strength and Marrow Adiposity in Rats Fed with High-Carbohydrate High-Fat Diet
Sophia Ogechi Ekeuku, Khairun-Nisa Hashim, Jen Kit Tan, Michelle Yee Min Fang, Nur Zuliani Ramli, Khairul Anwar Zarkasi, Kok-Yong Chin, Fairus Ahmad
Int. J. Med. Sci. 2025; 22(14): 3802-3814. doi:10.7150/ijms.115978
Full text PDF

Reviews

Graphic abstract

Association Between Gut Microbiota and Pneumonia Risk: A Systematic Review and Mendelian Randomization
Qingping Deng, Yuanyuan Liu, Hui Rong, Qing Liu, Rongyuan Yang
Int. J. Med. Sci. 2025; 22(14): 3511-3527. doi:10.7150/ijms.114372
Full text PDF

Graphic abstract

Metabolism and Targeted Therapy of Fibrosis in Chronic Pancreatitis: A Review
Hongqing Luo, Shan Guo, Yuning Chu, Yiping Xin, Xiaoyan Yin, Xiaoyu Li
Int. J. Med. Sci. 2025; 22(14): 3528-3542. doi:10.7150/ijms.118338
Full text PDF

Graphic abstract

Role of Metabolic Abnormalities During the Progression of Chronic Kidney Disease and Preventive Strategies
Dongqing Zha, Ping Gao, Xiaoyan Wu
Int. J. Med. Sci. 2025; 22(14): 3543-3555. doi:10.7150/ijms.114382
Full text PDF

Graphic abstract

Overcoming the Delivery Challenges in CRISPR/Cas9 Gene Editing for Effective Cancer Treatment: A Review of Delivery Systems
Shuting Tang, Xiaoyi Chen, Xiangmin Tong, Lifen Zhu
Int. J. Med. Sci. 2025; 22(14): 3625-3649. doi:10.7150/ijms.112724
Full text PDF

Graphic abstract

Mesenchymal Stem Cells Senescence: Mechanism and Rejuvenation Interventions
Qinghong Meng, Yan Zheng, Xiaobo Chen, Jiawei Mu, Changlin Li, Yiwen Gao, Wei Liu, Yuliang Wang
Int. J. Med. Sci. 2025; 22(14): 3692-3708. doi:10.7150/ijms.115650
Full text PDF

Graphic abstract

Health-Related Quality of Life in Patients with Hepatocellular Carcinoma Post-Surgery: A Scoping Review
Wei-Zheng Zhang, Kok-Yong Chin, Roshaya Zakaria, Nor Haty Hassan
Int. J. Med. Sci. 2025; 22(14): 3709-3721. doi:10.7150/ijms.115946
Full text PDF

Popup Image

©2025 Ivyspring International Publisher. Terms of use