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Volume 23 (8); 2026

Research Papers

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Genetic Variants in the MTHFR and WNK1 Genes and Their Contribution to Hypertension Susceptibility Laith N. AL-Eitan, Ola M. Al-Sanabra, Fouad A. Almomani, Maryam K. Alasmar, Mariam R. Alrejjal, Zeina F. Obeid, Ra'ed I. AlRabadi Int. J. Med. Sci. 2026; 23(8): 2499-2510. doi:10.7150/ijms.133244 Full text PDF

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Exploratory Immunophenotyping of Programmed cell death-1 (PD-1) Expression and Regulatory T-Cell (Treg) Profiles in Systemic Lupus Erythematosus and Healthy Controls: A Cohort Study with Illustrative Clinical Cases Po-Jen Hsiao, Jeng-Wei Lu, Yi-Jung Ho, Shan-Wen Lui, Ting-Yu Hsieh, Wun-Long Jheng, Anna Blyzniuk, Feng-Cheng Liu Int. J. Med. Sci. 2026; 23(8): 2511-2523. doi:10.7150/ijms.131673 Full text PDF

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Targeting the Extracellular Signal-Regulated Kinase 5-Cellular Jun-Vimentin Axis to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Patients with Triple-Negative Breast Cancer Chia-Chi Chen, Shu-Jyuan Chang, Cheng-Loong Liang, Hieu D. H. Nguyen, Chi-Wen Luo, Yi-Zi Chen, Yu-Tzu Yang, Mei-Chiang Hsu, Sin-Hua Moi, Chao-Ming Hung, Mei-Ren Pan Int. J. Med. Sci. 2026; 23(8): 2524-2539. doi:10.7150/ijms.131682 Full text PDF

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Interplay of Atrial Arrhythmia and Chronic Heart Failure: A Population-Based Analysis of Hospital Outcomes in Germany Anastasia Janina Hobbach, Jannik Feld, Jürgen Reinhard Sindermann, Wolfgang Albrecht Linke, Holger Reinecke Int. J. Med. Sci. 2026; 23(8): 2540-2547. doi:10.7150/ijms.131856 Full text PDF

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Computational Discovery of Angiotensin-(1-7)-like Peptides Targeting the MAS Receptor from the Genomic Dark Matter of Saccharomyces cerevisiae Pattayampadam Ramakrishnan Shidhi, Aiswarya Jayaprakash, Navya Raj, Peramaiyan Rajendran, Rebai Ben Ammar, Biju Vadakkemukadiyil Chellapan Int. J. Med. Sci. 2026; 23(8): 2568-2577. doi:10.7150/ijms.135093 Full text PDF

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C1q CIC in Lupus Nephritis: An Analysis of 883 Patients Huang-Chen Chang, Yen-Ching Wu, Jun-Peng Chen, Wen-Nan Huang, Yi-Hsing Chen, Yi-Ming Chen Int. J. Med. Sci. 2026; 23(8): 2578-2586. doi:10.7150/ijms.125522 Full text PDF

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Licoricidin triggers reactive oxygen species-mediated PANoptosis in human hepatocellular carcinoma cells Ming-Chun Hung, Hui-Ling Chiou, Yi-Hsien Hsieh, Pei-Ni Chen, Yung-Luen Yu, Hsiang-Lin Lee Int. J. Med. Sci. 2026; 23(8): 2610-2620. doi:10.7150/ijms.132175 Full text PDF

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Multi-Omics and Clinical Data Analyses of Protein Arginine Methyltransferases in Pan-Cancer and Colorectal Cancer Jialing Xie, Qihui Wu, Yuanyuan Xu, Jiaxin Liu, Yan Wang, Xuan Wang, Xiaodan Fu, Yimin Li Int. J. Med. Sci. 2026; 23(8): 2621-2636. doi:10.7150/ijms.129345 Full text PDF

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WISP-3 promotes tumor-monocyte adhesion through a MEK/ERK-dependent miR-12131/ICAM-4 axis in lung adenocarcinoma Chia-Chia Chao, Syuan-Ling Lin, Yu-Chen Chen, Ching-Yuan Cheng, En-Ming Chang, Chih-Hsin Tang, Chih-Yang Lin Int. J. Med. Sci. 2026; 23(8): 2637-2646. doi:10.7150/ijms.136597 Full text PDF

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Inhibition of UBE2N enhances TRAIL-mediated apoptosis through upregulation of DR5 in cancer cells Yu Jin Jeong, Seon Min Woo, Seung Un Seo, So Rae Song, Taeg Kyu Kwon Int. J. Med. Sci. 2026; 23(8): 2647-2656. doi:10.7150/ijms.130235 Full text PDF

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Cyr61 Promotes Oral Squamous Cell Carcinoma Cell Motility via an Integrin αvβ3/αvβ5-PLC/PKC/c-Src-AP-1-ICAM-1 Signaling Axis Kuan-Chou Lin, Pei-Wen Peng, Tsung-Ming Chang, Ying-Sui Sun, Chih-Hsin Tang, Ju-Fang Liu, Chia-Jung Lee Int. J. Med. Sci. 2026; 23(8): 2657-2669. doi:10.7150/ijms.133127 Full text PDF

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Eosinophilic Esophagitis and Risk of Non-Alcoholic Fatty Liver Disease and Cirrhosis: A Multi-Center Retrospective Study Shuo-Yan Gau, Yu-Jung Su, Shih-Chi Yang, Chih-Lung Wu, Solomon Chih-Cheng Chen, Hui-Chin Chang, Meng-Che Wu Int. J. Med. Sci. 2026; 23(8): 2670-2678. doi:10.7150/ijms.123768 Full text PDF

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CLEC3B (tetranectin) expression is associated with vascular localization and tumor aggressiveness in breast cancer Ching-Ting Wei, Teng-Hung Yu, Chia-Chang Hsu, Chin-Feng Hsuan, Wei-Chin Hung, Chao-Ping Wang, Wei-Hua Tang, Fu-Mei Chung, Yau-Jiunn Lee, Chi-Chang Chang, Chia-Chi Chen Int. J. Med. Sci. 2026; 23(8): 2715-2727. doi:10.7150/ijms.132030 Full text PDF

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Long-Term Trends in Microbiology and Outcomes of Pediatric Deep Neck Infections: An 18-Year Study Fang-Ching Liu, Pei-Rung Yang, Yao-Te Tsai, Yao-Hsu Yang, Chia-Yen Liu, Geng-He Chang Int. J. Med. Sci. 2026; 23(8): 2728-2738. doi:10.7150/ijms.131187 Full text PDF

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Comparison of Emergence Agitation Between Remimazolam- and Propofol-Based Anesthetic Induction in Patients Undergoing Transurethral Endoscopic Urologic Surgery: A Propensity Score-Matched Retrospective Study Ji-Yoon Jung, Hwang-Ju You, Woojin Kwon, Junho Kim, Tae-Yun Sung Int. J. Med. Sci. 2026; 23(8): 2739-2746. doi:10.7150/ijms.137664 Full text PDF

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Risk of Peripheral Artery Disease and Venous Thromboembolism in Patients with Neuromyelitis Optic Spectrum Disorder: A Nationwide Population-Based Cohort Study Xin-An Chen, Chun-Nan Wu, Tung-Han Tsai, Chien-Yu Lin, Hsuan Chang, Shuo-Yan Gau, Kuang-Hua Huang, Chien-Ying Lee Int. J. Med. Sci. 2026; 23(8): 2747-2757. doi:10.7150/ijms.130836 Full text PDF

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The Marine Triterpene Stellettin B Triggers Mitochondrial-to-Nuclear Translocation of AIF/EndoG and Reverses Epithelial-Mesenchymal Transition to Inhibit Oral Cancer Progression Peng-Yu Chen, Pin-Chen Kuo, Yi-Lung Ling, Yen-Yun Wang, Shyng-Shiou F. Yuan, Jyh-Horng Sheu, Wan-Chi Tsai Int. J. Med. Sci. 2026; 23(8): 2758-2766. doi:10.7150/ijms.134063 Full text PDF

Reviews

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Advances in Artificial Intelligence for Wrist Joint Injury Diagnosis Hong Li, Xilin Liu Int. J. Med. Sci. 2026; 23(8): 2548-2567. doi:10.7150/ijms.134301 Full text PDF

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Migration of Cardiac Cells: Hot Topics that have not Attracted Clinical Attention Jie Ma, Yaping Xu, Yali Wang, Zhikun Guo Int. J. Med. Sci. 2026; 23(8): 2587-2609. doi:10.7150/ijms.130458 Full text PDF

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ZDHHC-Mediated Protein S-Palmitoylation in Cancer: Epigenetic Interfaces, Structural Logic and Therapeutic Targeting Xinyi Chen, Duo Xu, Yongbiao Huang, Xianglin Yuan Int. J. Med. Sci. 2026; 23(8): 2679-2714. doi:10.7150/ijms.130609 Full text PDF

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