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Volume 18 (13); 2021

Research Papers

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Exercise capacity, cardiovascular and metabolic risk of the sample of German police officers in a descriptive international comparison
Markus Strauss, Peter Foshag, Ulrich Jehn, Richard Vollenberg, Anna Brzęk, Roman Leischik
Int. J. Med. Sci. 2021; 18(13): 2767-2775. doi:10.7150/ijms.60696
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Frequency of lower extremity artery disease in type 2 diabetic patients using pulse oximetry and the ankle-brachial index
Mosquera-Fernández Abián, Balboa-Barreiro Vanesa, Bellido-Guerrero Diego, González-Sagrado Manuel, Vale-Carrodeguas Maria, Veiga-Seijo Raquel, González-Martín Cristina
Int. J. Med. Sci. 2021; 18(13): 2776-2782. doi:10.7150/ijms.58907
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Effect of Ambulance Stretcher Bed Height Adjustment on CPR Quality and Rescuer Fatigue in a Laboratory Environment
Chun-Sheng Ho, Yi-Ju Hsu, Fang Li, Chien-Ching Tang, Cheng-Pang Yang, Chi-Chang Huang, Chin-Shan Ho, Chun-Hao Chang
Int. J. Med. Sci. 2021; 18(13): 2783-2788. doi:10.7150/ijms.59037
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multi-biomarker is an early-stage predictor for progression of Coronavirus disease 2019 (COVID-19) infection
Zheng Zhou, Ying Li, Yuanhui Ma, Heng Zhang, Yunfeng Deng, Zuobin Zhu
Int. J. Med. Sci. 2021; 18(13): 2789-2798. doi:10.7150/ijms.58742
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Abnormal proinflammatory and stressor environmental with increased the regulatory cellular IGF-1/PAPP-A/STC and Wnt-1/β-Catenin canonical pathway in placenta of women with Chronic venous Disease during Pregnancy
Miguel A Ortega, Oscar Fraile-Martínez, Miguel A Saez, Miguel A Álvarez-Mon, Ana M Gómez-Lahoz, Coral Bravo, Juan A De León Luis, Felipe Sainz, Santiago Coca, Ángel Asúnsolo, Jorge Monserrat, Luis G Guijarro, Melchor Álvarez-Mon, Julia Bujan, Natalio García-Honduvilla
Int. J. Med. Sci. 2021; 18(13): 2814-2827. doi:10.7150/ijms.58992
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prediction of lymphovascular space invasion in patients with endometrial cancer
Sang Il Kim, Joo Hee Yoon, Sung Jong Lee, Min Jong Song, Jin Hwi Kim, Hae Nam Lee, Gyul Jung, Ji Geun Yoo
Int. J. Med. Sci. 2021; 18(13): 2828-2834. doi:10.7150/ijms.60718
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Salmonella reduces tumor metastasis by downregulation C-X-C chemokine receptor type 4
Tai-Huang Lee, Gaun-You Lin, Ming-Hui Yang, Yu-Chang Tyan, Che-Hsin Lee
Int. J. Med. Sci. 2021; 18(13): 2835-2841. doi:10.7150/ijms.60439
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Effects of renal impairment on cardiac remodeling and clinical outcomes after myocardial infarction
Chun-Yen Chiang, Sheng-Chung Huang, Michael Chen, Jhih-Yuan Shih, Chon-Seng Hong, Nan-Chun Wu, Chung-Han Ho, Chia Chun Wu, Zhih-Cherng Chen, Wei-Ting Chang
Int. J. Med. Sci. 2021; 18(13): 2842-2848. doi:10.7150/ijms.61891
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Role of Unfolded Protein Response and Endoplasmic Reticulum-Associated Degradation by Repeated Exposure to Inhalation Anesthetics in Caenorhabditis elegans
Saeyeon Kim, Hyun-Jung Shin, Sang-Hwan Do, Hyo-Seok Na
Int. J. Med. Sci. 2021; 18(13): 2890-2896. doi:10.7150/ijms.58043
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Evaluation of atherogenic lipoprotein-cholesterol to HDL cholesterol ratio as a prognostic test for ST-segment elevation myocardial infarction
Jia-Yong Li, Wen-Jun Xu, Zhe Zhou, Ru-lin Zhang, Ting Sun, Hao Xu, Jun Wu
Int. J. Med. Sci. 2021; 18(13): 2897-2904. doi:10.7150/ijms.44801
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Association of QRS-T angle and Late Gadolinium Enhancement in patients with a Clinical Suspicion of Myocarditis
C.J. Jensen, B. Zadeh, J.M. Wambach, M. Lambers, K. Nassenstein, O. Bruder
Int. J. Med. Sci. 2021; 18(13): 2905-2909. doi:10.7150/ijms.57010
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Effect of MT2A on apoptosis and proliferation in HL60 cells
Yu-Qing Pan, Min Niu, Shu-min Liu, Yu-Xia Bao, Kai Yang, Xiao-Bo Ma, Liang He, Yi-Xun Li, Jie-Xian Cao, Xi Zhang, Yan Du
Int. J. Med. Sci. 2021; 18(13): 2910-2919. doi:10.7150/ijms.57821
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Selective brain cooling achieves peripheral organs protection in hemorrhagic shock resuscitation via preserving the integrity of the brain-gut axis
Chien-Ming Chao, Chien-Chin Hsu, Chien-Cheng Huang, Chung-Han Wang, Mao-Tsun Lin, Ching-Ping Chang, Hung-Jung Lin, Chung-Ching Chio
Int. J. Med. Sci. 2021; 18(13): 2920-2929. doi:10.7150/ijms.61191
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Enhancement of cytotoxicity and induction of apoptosis by cationic nano-liposome formulation of n-butylidenephthalide in breast cancer cells
Xiao-Fan Huang, Kai-Fu Chang, Yu-Ling Lin, Kuang-Wen Liao, Chih-Yen Hsiao, Gwo-Tarng Sheu, Nu-Man Tsai
Int. J. Med. Sci. 2021; 18(13): 2930-2942. doi:10.7150/ijms.51439
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Distinct Patterns of Brain Atrophy associated with Mild Behavioral Impairment in Cognitively Normal Elderly Adults
Jun Shu, Qiang Qiang, Yuning Yan, Yang Wen, Yiqing Ren, Wenshi Wei, Li Zhang
Int. J. Med. Sci. 2021; 18(13): 2950-2956. doi:10.7150/ijms.60810
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Factors associated with Successful Responses to Ganglion Impar Block: A Retrospective Study
Chan-Sik Kim, Kyounghwan Jang, Jeong-Gil Leem, Jin-Woo Shin, Doo-Hwan Kim, Seong-Soo Choi
Int. J. Med. Sci. 2021; 18(13): 2957-2963. doi:10.7150/ijms.60962
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Lower serum bilirubin is associated with poor renal outcome in IgA nephropathy patients
Zheng Jiang, Jiaxing Tan, Siqing Wang, Lingqiu Dong, Xin Han, Yi Tang, Wei Qin
Int. J. Med. Sci. 2021; 18(13): 2964-2970. doi:10.7150/ijms.60111
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Efficacy of bisphosphonates in detection of early enamel caries using NIR fluorescence imaging and inhibition of caries progression
Jie Sun, Mindy Gil, Shahrzad Khorashadi, George Chen, Cliff Lee, Yoshiki Ishida, Masazumi Nagai, Shinichiro Wada, Shigemi Ishikawa-Nagai, John D Da Silva
Int. J. Med. Sci. 2021; 18(13): 2971-2980. doi:10.7150/ijms.60013
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Salmonella alters heparanase expression and reduces tumor metastasis
Huan-Min Chiu, Wen- Yi Chiou, Wei-Jie Hsu, Li-Hsien Wu, Ming-Hui Yang, Yu-Chang Tyan, Che-Hsin Lee
Int. J. Med. Sci. 2021; 18(13): 2981-2989. doi:10.7150/ijms.60281
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Determination of Bioelectrical Impedance Thresholds for Early Detection of Breast Cancer-related Lymphedema
Siyao Liu, Quanping Zhao, Xinmei Ren, Ying Cui, Houpu Yang, Siyuan Wang, Miao Liu, Shu Wang
Int. J. Med. Sci. 2021; 18(13): 2990-2996. doi:10.7150/ijms.53812
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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TRIM21 Polymorphisms are associated with Susceptibility and Clinical Status of Oral Squamous Cell Carcinoma patients
Chun-Yi Chuang, Yi-Chung Chien, Chiao-Wen Lin, Chia-Hsuan Chou, Shuo-Chueh Chen, Chun-Lin Liu, Li-Yuan Bai, Shun-Fa Yang, Yung-Luen Yu
Int. J. Med. Sci. 2021; 18(13): 2997-3003. doi:10.7150/ijms.56614
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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CD8+ T cell survival in lethal fungal sepsis was ameliorated by T-cell-specific mTOR deletion
Hao Wang, Wen Han, Ran Guo, Guangxu Bai, Jianwei Chen, Na Cui
Int. J. Med. Sci. 2021; 18(13): 3004-3013. doi:10.7150/ijms.55592
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Experimental postoperative ileus: is Th2 immune response involved?
Sisi Lin, Florian Kühn, Tobias S. Schiergens, Andrey A. Zamyatnin, Orkhan Isayev, Eldar Gasimov, Jens Werner, Yongyu Li, Alexandr V. Bazhin
Int. J. Med. Sci. 2021; 18(13): 3014-3025. doi:10.7150/ijms.59354
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The underlying molecular mechanism and drugs for treatment in adrenal cortical carcinoma
Chengquan Ma, Jian Xiong, Hao Su, Hongjun Li
Int. J. Med. Sci. 2021; 18(13): 3026-3038. doi:10.7150/ijms.60261
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Antitumor Activity of Small Activating RNAs Induced PAWR Gene Activation in Human Bladder Cancer Cells
Kai Yang, Jie Shen, Fu-Qing Tan, Xiang-Yi Zheng, Li-Ping Xie
Int. J. Med. Sci. 2021; 18(13): 3039-3049. doi:10.7150/ijms.60399
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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The Molecular Genetics of Marfan Syndrome
Qiu Du, Dingding Zhang, Yue Zhuang, Qiongrong Xia, Taishen Wen, Haiping Jia
Int. J. Med. Sci. 2021; 18(13): 2752-2766. doi:10.7150/ijms.60685
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy
Xiao-bo Zhang, Yi-cun Hu, Peng Cheng, Hai-yu Zhou, Xiang-yi Chen, Ding Wu, Rui-hao Zhang, De-chen Yu, Xi-dan Gao, Jin-tao Shi, Kai Zhang, Shao-long Li, Peng-jie Song, Ke-ping Wang
Int. J. Med. Sci. 2021; 18(13): 2799-2813. doi:10.7150/ijms.59171
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Clinical applications of mesenchymal stromal cell-based therapies for pulmonary diseases: An Update and Concise Review
Xiaobo Chen, Feng Wang, Zhiwei Huang, Yan Wu, Jie Geng, Yuliang Wang
Int. J. Med. Sci. 2021; 18(13): 2849-2870. doi:10.7150/ijms.59218
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Artificial Intelligence and Machine Learning in Chronic Airway Diseases: Focus on Asthma and Chronic Obstructive Pulmonary Disease
Yinhe Feng, Yubin Wang, Chunfang Zeng, Hui Mao
Int. J. Med. Sci. 2021; 18(13): 2871-2889. doi:10.7150/ijms.58191
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Designing Nanoparticle-based Drug Delivery Systems for Precision Medicine
Jianhua Yang, Chengyou Jia, Jianshe Yang
Int. J. Med. Sci. 2021; 18(13): 2943-2949. doi:10.7150/ijms.60874
[Abstract] [Full text] [PDF] [PubMed] [PMC]