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Volume 22 (16); 2025

Research Papers

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Endothelin-1 Stimulates the Growth of Visceral and Subcutaneous Human Preadipocytes through Similar and Alternative Signaling Pathways via Type A and Type B Endothelin Receptors: Potential Implications for Therapeutic Strategies for Obesity and Metabolic Disorders
An-Ci Siao, Yung-Hsi Kao, Chih-Chun Kuo, Hann-Yeh Shyu, Yow-Chii Kuo, Wen-Fang Chiang, Kuo-An Wu, Li-Jane Shih, Po-Jen Hsiao
Int. J. Med. Sci. 2025; 22(16): 4161-4174. doi:10.7150/ijms.110073
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Stage-dependent EZH2 methylation correlates with immune polarization, metabolic suppression, and unfavorable outcomes in hepatocellular carcinoma
Yi-Chung Chien, Guo-Wei Wu, Jia-Yan Wu, Liang-Chih Liu, Yi-Hsien Hsieh, Yung-Luen Yu
Int. J. Med. Sci. 2025; 22(16): 4201-4213. doi:10.7150/ijms.119496
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Aberrant ALPP Expression Serves as a Prognostic Biomarker and Facilitates Cholangiocarcinoma Progression through Immune Evasion and PI3K-Akt Signaling Activation
Guo-Wei Wu, Yi-Chung Chien, Li-Yuan Bai, Yung-Luen Yu
Int. J. Med. Sci. 2025; 22(16): 4214-4226. doi:10.7150/ijms.116260
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Association Between Cardiopulmonary Fitness and Degenerative Lumbar Spine Disease in Patients with Heart Failure: a Retrospective Study Using CPET
Zong-Han Lin, Sheng-Hui Tuan, Ko-Long Lin, Wen-Hwa Wang, Wan-Yun Huang, Shu-Fen Sun, Ruei-Sian Ding, I-Hsiu Liou
Int. J. Med. Sci. 2025; 22(16): 4227-4235. doi:10.7150/ijms.121138
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Real-Time Ultrasound Diagnosis of Developmental Dysplasia of the Hip Using an Attention-Enhanced YOLOv11 Model
Wen-Shin Hsu, Guang-Tao Lin, Wei-Hsun Wang
Int. J. Med. Sci. 2025; 22(16): 4236-4249. doi:10.7150/ijms.120138
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Reviews

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Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review
Siti Balqis Adnan, Manira Maarof, Mh Busra Fauzi, Nur Izzah Md Fadilah
Int. J. Med. Sci. 2025; 22(16): 4175-4200. doi:10.7150/ijms.118118
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Bispecific Antibodies in Glioblastoma: Mechanistic Advances, Delivery Innovations, and Translational Challenges in Overcoming Immune Escape
He-Lu Wang, Nan Chi, Hong-Tao Zhang
Int. J. Med. Sci. 2025; 22(16): 4250-4277. doi:10.7150/ijms.121829
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