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Volume 18 (5); 2021

Research Papers

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Microvascular Reactivity Measured by Dynamic Near-infrared Spectroscopy Following Induction of General Anesthesia in Healthy Patients: Observation of Age-related Change
Ah-Reum Cho, Hyeon-Jeong Lee, Hyae-Jin Kim, Wangseok Do, Soeun Jeon, Seung-Hoon Baek, Eun-Soo Kim, Jae-Young Kwon, Hae-Kyu Kim
Int. J. Med. Sci. 2021; 18(5): 1096-1103. doi:10.7150/ijms.52433
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome
Wan-Hua Tsai, Chia-Hsuan Chou, Ying-Ju Chiang, Ching-Gong Lin, Che-Hsin Lee
Int. J. Med. Sci. 2021; 18(5): 1114-1120. doi:10.7150/ijms.51545
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Differences in detected safety signals between benzodiazepines and non-benzodiazepine hypnotics: pharmacovigilance study using a spontaneous reporting system
Manabu Toyoshima, Yoshihiro Noguchi, Manami Otsubo, Tomoya Tachi, Hitomi Teramachi
Int. J. Med. Sci. 2021; 18(5): 1130-1136. doi:10.7150/ijms.51658
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Virus discharge and initial gastrointestinal involvement are inversely associated with circulating lymphocyte count in COVID-19
Wei Chen, Kenneth I. Zheng, Saiduo Liu, Chongyong Xu, Chao Xing, Zengpei Qiao
Int. J. Med. Sci. 2021; 18(5): 1137-1142. doi:10.7150/ijms.51672
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis
Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Hsin-Liang Liu, Chih-Yang Wang, Hui-Ping Hsu
Int. J. Med. Sci. 2021; 18(5): 1143-1152. doi:10.7150/ijms.52256
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Minimally invasive surgery for patients with advanced stage endometrial cancer
Sang Il Kim, Dong Choon Park, Sung Jong Lee, Ji Geun Yoo, Min Jong Song, Chan Joo Kim, Hae Nam Lee, Joo Hee Yoon
Int. J. Med. Sci. 2021; 18(5): 1153-1158. doi:10.7150/ijms.52293
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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INR-to-platelet ratio (INPR) as a novel noninvasive index for predicting liver fibrosis in chronic hepatitis B
Rongrong Ding, Jianming Zheng, Dan Huang, Yanbing Wang, Xiufen Li, Xinlan Zhou, Li Yan, Wei Lu, Zongguo Yang, Zhanqing Zhang
Int. J. Med. Sci. 2021; 18(5): 1159-1166. doi:10.7150/ijms.51799
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The efficacy and safety of Hirudin plus Aspirin versus Warfarin in the secondary prevention of Cardioembolic Stroke due to Nonvalvular Atrial Fibrillation: A multicenter prospective cohort study
Chang-geng Song, Li-jie Bi, Jing-jing Zhao, Xuan Wang, Wen Li, Fang Yang, Wen Jiang
Int. J. Med. Sci. 2021; 18(5): 1167-1178. doi:10.7150/ijms.52752
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Timing of mTORI usage and outcomes in kidney transplant recipients
Lee-Moay Lim, Lan-Fang Kung, Mei-Chuan Kuo, A-Mei Huang, Hung-Tien Kuo
Int. J. Med. Sci. 2021; 18(5): 1179-1184. doi:10.7150/ijms.53655
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Impact on physical and mental health among medical personnel in Wuhan during COVID-19 outbreak: a cluster analysis
Jing Gao, Jing Li, Xia Han, Yuan Yuan, Chuan-Xing Li, Dong-Quan Zhang
Int. J. Med. Sci. 2021; 18(5): 1185-1188. doi:10.7150/ijms.51315
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prolonged preoperative fasting induces postoperative insulin resistance by ER-stress mediated Glut4 down-regulation in skeletal muscles
Ming-Wei Lin, Chih-I Chen, Tzu-Ting Cheng, Chien-Chi Huang, Jen-Wei Tsai, Guan-Ming Feng, Tzer-Zen Hwang, Chen-Fuh Lam
Int. J. Med. Sci. 2021; 18(5): 1189-1197. doi:10.7150/ijms.52701
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Risk factors for mortality of critically ill patients with COVID-19 receiving invasive ventilation
Ye Tu, Ping Yang, Yaqun Zhou, Xiaoyan Wen, Qinqin Li, Jing Zhou, Jingjing Wang, Jinqian Hu, Nannan He, Kai Wang, Chaolong Wang, Xuebi Tian, Ailin Luo, Feng Gao
Int. J. Med. Sci. 2021; 18(5): 1198-1206. doi:10.7150/ijms.50039
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification of parameters in routine blood and coagulation tests related to the severity of COVID-19
Rongrong Ding, Zongguo Yang, Dan Huang, Yanbing Wang, Xiufen Li, Xinlan Zhou, Li Yan, Wei Lu, Zhanqing Zhang
Int. J. Med. Sci. 2021; 18(5): 1207-1215. doi:10.7150/ijms.47494
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identifying daily changes in circRNAs and circRNA-associated-ceRNA networks in the rat pineal gland
Yi Zheng, Hao Jiang, Hao-Qi Wang, Hai-Xiang Guo, Dong-Xu Han, Yi-Jie Huang, Yan Gao, Bao Yuan, Jia-Bao Zhang
Int. J. Med. Sci. 2021; 18(5): 1225-1239. doi:10.7150/ijms.51743
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Incidence and treatment of adult femoral fractures with osteogenesis imperfecta: An analysis of a center of 72 patients in Taiwan
Chung-Lin Lee, Shih-Chia Liu, Chen-Yu Yang, Chih-Kuang Chuang, Hsiang-Yu Lin, Shuan-Pei Lin
Int. J. Med. Sci. 2021; 18(5): 1240-1246. doi:10.7150/ijms.53286
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Di-(2-ethylhexyl) phthalate-induced tumor growth is regulated by primary cilium formation via the axis of H2O2 production-thymosin beta-4 gene expression
Jae-Wook Lee, Pham Xuan Thuy, Hae-Kyoung Han, Eun-Yi Moon
Int. J. Med. Sci. 2021; 18(5): 1247-1258. doi:10.7150/ijms.53595
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Hematological patterns and histopathological assessment of Miniature Pigs in the experiments on human mesenchymal stem cell transplantation
Young-Bum Son, Dinesh Bharti, Saet-Byul Kim, Eun-Yeong Bok, Sang-Yeob Lee, Han-Jang Ho, Sung-Lim Lee, Gyu-Jin Rho
Int. J. Med. Sci. 2021; 18(5): 1259-1268. doi:10.7150/ijms.53036
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Drug Resistance of CPT-11 in Human DLD-1 Colorectal Cancer Cells through MutS Homolog 2 Upregulation
Ko-Chao Lee, Chia-Kung Yen, Cheng-Nan Chen, Shun-Fu Chang, Ying-Chen Lu, Wen-Shih Huang
Int. J. Med. Sci. 2021; 18(5): 1269-1276. doi:10.7150/ijms.52620
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Longitudinal changes in COVID-19 clinical measures and correlation with the extent of CT lung abnormalities
Min Zhou, Chengjun Dong, Chungao Li, Yuhui Wang, Huijun Liao, Heshui Shi, Alexander Peter Lin, Jing Wang, Yue Hu, Chuansheng Zheng
Int. J. Med. Sci. 2021; 18(5): 1277-1284. doi:10.7150/ijms.51279
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Is liver involvement overestimated in COVID-19 patients? A meta-analysis
Gang Li, Yitian Yang, Danyang Gao, Yongxing Xu, Jianwen Gu, Pengfei Liu
Int. J. Med. Sci. 2021; 18(5): 1285-1296. doi:10.7150/ijms.51174
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification novel prognostic signatures for Head and Neck Squamous Cell Carcinoma based on ceRNA network construction and immune infiltration analysis
Haiting Zhou, Yi He, Lingling Li, Cheng Wu, Guoqing Hu
Int. J. Med. Sci. 2021; 18(5): 1297-1311. doi:10.7150/ijms.53531
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Comparison of abdominal and minimally invasive radical hysterectomy in patients with early stage cervical cancer
Sang Il Kim, Jiwoo Lee, Jiyun Hong, Sung Jong Lee, Dong Choon Park, Joo Hee Yoon
Int. J. Med. Sci. 2021; 18(5): 1312-1317. doi:10.7150/ijms.55017
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Macrophage Polarization and Liver Ischemia-Reperfusion Injury
Hai Wang, Zhifeng Xi, Lu Deng, Yixiao Pan, Kang He, Qiang Xia
Int. J. Med. Sci. 2021; 18(5): 1104-1113. doi:10.7150/ijms.52691
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Environmental Pollution and Chronic Kidney Disease
Hui-Ju Tsai, Pei-Yu Wu, Jiun-Chi Huang, Szu-Chia Chen
Int. J. Med. Sci. 2021; 18(5): 1121-1129. doi:10.7150/ijms.51594
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Src-family Protein Tyrosine Kinases: A promising target for treating Cardiovascular Diseases
Yuhong Zhai, Jun Yang, Jing Zhang, Jian Yang, Qi Li, Tao Zheng
Int. J. Med. Sci. 2021; 18(5): 1216-1224. doi:10.7150/ijms.49241
[Abstract] [Full text] [PDF] [PubMed] [PMC]