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Volume 18 (15); 2021

Research Papers

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Cellular and Tissue Selectivity of AAV Serotypes for Gene Delivery to Chondrocytes and Cartilage
Dong Suk Yoon, Kyoung-Mi Lee, Sehee Cho, Eun Ae Ko, Jihyun Kim, Sujin Jung, Jae-Hyuck Shim, Guangping Gao, Kwang Hwan Park, Jin Woo Lee
Int. J. Med. Sci. 2021; 18(15): 3353-3360. doi:10.7150/ijms.56760
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Antenatal Betamethasone Induces Increased Surfactant Proteins and Decreased Foxm1 Expressions in Fetal Rabbit Pups
Yong-Sung Choi, Chae-Young Kim, Hye Kyung Chang, Young Joo Lee, Sung-Hoon Chung
Int. J. Med. Sci. 2021; 18(15): 3367-3372. doi:10.7150/ijms.62286
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Otorhinolaryngological Management in Taiwanese Patients with Mucopolysaccharidoses
Chung-Lin Lee, Kuo-Sheng Lee, Chih-Kuang Chuang, Chin-Hui Su, Huei-Ching Chiu, Ru-Yi Tu, Yun-Ting Lo, Ya-Hui Chang, Hsiang-Yu Lin, Shuan-Pei Lin
Int. J. Med. Sci. 2021; 18(15): 3373-3379. doi:10.7150/ijms.61827
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The combination therapy with EpCAM/CD3 BsAb and MUC-1/CD3 BsAb elicited antitumor immunity by T-cell adoptive immunotherapy in lung cancer
Ce Wang, Shang Chen, Yingjuan Wu, Di Wu, Jingbo Wang, Furong Li
Int. J. Med. Sci. 2021; 18(15): 3380-3388. doi:10.7150/ijms.61681
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Chest CT abnormalities in COVID-19: a systematic review
Ramy Abou Ghayda, Keum Hwa Lee, Jae Seok Kim, Seul Lee, Sung Hwi Hong, Kyeong Seok Kim, Kyeong Eon Kim, Jinhyn Seok, Hajeong Kim, Jangsuk Seo, Seungmin Lee, Ai Koyanagi, Louis Jacob, Lee Smith, Han Li, Andreas Kronbichler, Jae Il Shin
Int. J. Med. Sci. 2021; 18(15): 3395-3402. doi:10.7150/ijms.50568
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Cobalt chloride-stimulated hypoxia promotes the proliferation of cholesteatoma keratinocytes via the PI3K/Akt signaling pathway
Chen Zhang, Min Chen, Qi Tao, Zhangcai Chi
Int. J. Med. Sci. 2021; 18(15): 3403-3411. doi:10.7150/ijms.60617
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis
Ke Zhu, Aiqun Xu, Wanli Xia, Pulin Li, Rui Han, Enze Wang, Sijing Zhou, Ran Wang
Int. J. Med. Sci. 2021; 18(15): 3412-3424. doi:10.7150/ijms.61309
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Identification of Key Genes and Pathways associated with Endometriosis by Weighted Gene Co-expression Network Analysis
Jingni Wu, Xiaoling Fang, Xiaomeng Xia
Int. J. Med. Sci. 2021; 18(15): 3425-3436. doi:10.7150/ijms.63541
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1
Jing Han, Xin Chen, Jiawei Xu, Laili Chu, Rongqing Li, Na Sun, Zhen Jiang, Hongyang Liu, Xing Ge, Junnian Zheng, Jing Yang, Takayuki Ikezoe
Int. J. Med. Sci. 2021; 18(15): 3437-3451. doi:10.7150/ijms.61969
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Areca nut extract (ANE) inhibits the progression of hepatocellular carcinoma cells via activation of ROS production and activation of autophagy
Po-Li Wei, Chin-Sheng Hung, Hsuan-Hsuan Lu, Uyanga Batzorig, Chien-Yu Huang, Yu-Jia Chang
Int. J. Med. Sci. 2021; 18(15): 3452-3462. doi:10.7150/ijms.61570
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Verification of the Efficacy of New Diagnostic Criteria for Retropharyngeal Nodes in a Cohort of Nasopharyngeal Carcinoma Patients
Dom-Gene Tu, Hsuan-Yu Chen, Wei-Jen Yao, Yu-Sheng Hung, Yu-Kang Chang, Chih-Han Chang, Yu-Wen Wang
Int. J. Med. Sci. 2021; 18(15): 3463-3469. doi:10.7150/ijms.58375
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Sex Difference in the Associations among Obesity-Related Indices with Metabolic Syndrome in Patients with Type 2 Diabetes Mellitus
Hsiu-Fen Jao, Chih-Hsuan Wung, Hui-Chen Yu, Mei-Yueh Lee, Po-Chih Chen, Szu-Chia Chen, Jer-Ming Chang
Int. J. Med. Sci. 2021; 18(15): 3470-3477. doi:10.7150/ijms.63180
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Bioinformatics analysis identified shared differentially expressed genes as potential biomarkers for Hashimoto's thyroiditis-related papillary thyroid cancer
Chang Liu, Yu Pan, Qinyu Li, Yifan Zhang
Int. J. Med. Sci. 2021; 18(15): 3478-3487. doi:10.7150/ijms.63402
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Comparison of short- and long-axis nerve hydrodissection for carpal tunnel syndrome: A prospective randomized, single-blind trial
Si-Ru Chen, Tsung-Yen Ho, Yu-Ping Shen, Tsung-Ying Li, Yu-Chi Su, King Hei Stanley Lam, Liang-Cheng Chen, Yung-Tsan Wu
Int. J. Med. Sci. 2021; 18(15): 3488-3497. doi:10.7150/ijms.63815
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle
Jing Jing, Peng Xu, Jia-Li Xu, Yu-Xin Ding, Xiao-Shuang Yang, Xiao-Qin Jin, Li-Juan Zhou, Yu-Hong Chen, Xian-Jie Wu, Zhong-Fa Lu
Int. J. Med. Sci. 2021; 18(15): 3498-3505. doi:10.7150/ijms.60728
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Downregulation of circ_0000673 Promotes Cell Proliferation and Migration in Endometriosis via the Mir-616-3p/PTEN Axis
Yongwen Yang, Deying Ban, Chun Zhang, Licong Shen
Int. J. Med. Sci. 2021; 18(15): 3506-3515. doi:10.7150/ijms.63564
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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PLK1 Inhibition Induces Immunogenic Cell Death and Enhances Immunity against NSCLC
Jie Zhou, Qifan Yang, Lisen Lu, Zhan Tuo, Zhexing Shou, Jing Cheng
Int. J. Med. Sci. 2021; 18(15): 3516-3525. doi:10.7150/ijms.60135
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Risk factor comparison in young patients presenting with acute coronary syndrome with atherosclerotic coronary artery disease vs. angiographically normal coronaries
Sarah Jamil, Gohar Jamil, Hanaa Mesameh, Anwer Qureshi, Juma AlKaabi, Charu Sharma, Faisal Aziz, Ali Rashed Al-Shamsi, Javed Yasin
Int. J. Med. Sci. 2021; 18(15): 3526-3532. doi:10.7150/ijms.60869
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway
Xueqin Zhu, Jianjun Liu, Hao Pan, Zixiang Geng, William Huang, Te Liu, Bimeng Zhang
Int. J. Med. Sci. 2021; 18(15): 3544-3555. doi:10.7150/ijms.61975
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Roles of the miR-139-5p/CCT5 axis in hepatocellular carcinoma: a bioinformatic analysis
Jingjing Xu, Yuan Zhang, Cheng Liu, Ping Yan, Zongguo Yang
Int. J. Med. Sci. 2021; 18(15): 3556-3564. doi:10.7150/ijms.57504
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Risk of Pneumonia is associated with Antipsychotic Drug Use among older patients with Parkinson's Disease: A Case-control Study
Kuang-Hua Huang, Wei-Yin Kuo, Yu-Hsiang Kuan, Yu-Chia Chang, Tung-Han Tsai, Chien-Ying Lee
Int. J. Med. Sci. 2021; 18(15): 3565-3573. doi:10.7150/ijms.63246
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Polypharmacy Is Associated With Amiodarone-Induced Hypothyroidism
Satoshi Yokoyama, Yuki Tanaka, Kouichi Hosomi, Mitsutaka Takada
Int. J. Med. Sci. 2021; 18(15): 3574-3580. doi:10.7150/ijms.61412
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Plasma levels of amino acids and derivatives in retinopathy of prematurity
Yedi Zhou, Yu Xu, Xiang Zhang, Qian Huang, Wei Tan, Yonghui Yang, Xiaori He, Shigeo Yoshida, Peiquan Zhao, Yun Li
Int. J. Med. Sci. 2021; 18(15): 3581-3587. doi:10.7150/ijms.63603
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis
Peng Du, Kaifeng Luo, Guoyong Li, Jisheng Zhu, Qi Xiao, Yong Li, Xingjian Zhang
Int. J. Med. Sci. 2021; 18(15): 3588-3598. doi:10.7150/ijms.62467
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Predictive performance of eLIFT for liver inflammation and fibrosis in chronic liver diseases
Zongguo Yang, Xin Ma, Xinlan Zhou, Dan Huang, Yanbing Wang, Xiufen Li, Wei Lu, Zhanqing Zhang, Rongrong Ding
Int. J. Med. Sci. 2021; 18(15): 3599-3608. doi:10.7150/ijms.62386
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Impact of Motor Disability and the Level of Fatigue on Adherence to Therapeutic Recommendations in Patients with Multiple Sclerosis Treated with Immunomodulation
Robert Ślusarz, Joanna Olkiewicz, Robert Bonek, Karolina Filipska, Monika Biercewicz, Adam Wiśniewski
Int. J. Med. Sci. 2021; 18(15): 3609-3614. doi:10.7150/ijms.61964
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Role of “Stiff Rim” sign obtained by shear wave elastography in diagnosis and guiding therapy of breast cancer
Yan-jun Xu, Hui-ling Gong, Bin Hu, Bing Hu
Int. J. Med. Sci. 2021; 18(15): 3615-3623. doi:10.7150/ijms.64243
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Ferroptosis and Liver Fibrosis
Qi Pan, Yi Luo, Qiang Xia, Kang He
Int. J. Med. Sci. 2021; 18(15): 3361-3366. doi:10.7150/ijms.62903
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Hypothesis: Immunotherapy by Selective Convalescent Blood Engineering to Stifle Diseases like COVID-19
Arka Prava Mukherjee
Int. J. Med. Sci. 2021; 18(15): 3389-3394. doi:10.7150/ijms.46363
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Possible mechanisms of cholesterol elevation aggravating COVID-19
Yan Tang, Longtai Hu, Yi Liu, Bangyi Zhou, Xiaohuan Qin, Jujian Ye, Maoze Shen, Zhijian Wu, Peidong Zhang
Int. J. Med. Sci. 2021; 18(15): 3533-3543. doi:10.7150/ijms.62021
[Abstract] [Full text] [PDF] [PubMed] [PMC]