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Volume 22 (2); 2025

Research Papers

The association between grade of coronary heart disease and risk of developing keratopathy: a nationwide cohort study Chia-Yi Lee, Shun-Fa Yang, Jing-Yang Huang, Chao-Kai Chang Int. J. Med. Sci. 2025; 22(2): 252-259. doi:10.7150/ijms.101733 Full text PDF PubMed PMC

Association between maternal folic acid and/or multivitamin supplementation time and fetal congenital heart disease: based on the China birth cohort study Jingjing Wang, Simin Zhang, Lijuan Sun, Li Wang, Qingqing Wu Int. J. Med. Sci. 2025; 22(2): 260-268. doi:10.7150/ijms.102843 Full text PDF PubMed PMC

PUF60 Promotes Chemoresistance Through Drug Efflux and Reducing Apoptosis in Gastric Cancer Qianhui Liu, Yingqiu Song, Jing Su, Shangbin Yang, Qinghai Lian, Tiantian Wang, Hongbo Wei, Jiafeng Fang Int. J. Med. Sci. 2025; 22(2): 269-282. doi:10.7150/ijms.102976 Full text PDF PubMed PMC

Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats Sheng-Yow Ho, Chia-Hui Lin, Chien-Cheng Huang, Cheng-Hsien Lin, Mao-Tsun Lin, Ying-Jan Wang, Jui-Ti Ma, Li-Tsun Shieh, Ching-Ping Chang, Hung-Jung Lin Int. J. Med. Sci. 2025; 22(2): 283-297. doi:10.7150/ijms.104248 Full text PDF PubMed PMC

The Influence of Heart Rate on Peripheral Vascular Function Among Pacemaker Patients Md Rizman Md Lazin Md Lazim, Kalaivani Chellappan, Azizah Ugusman, W Yus Haniff W Isa, Mohd Shawal Faizal Mohamad, Wan Amir Nizam Wan Ahmad, Amilia Aminuddin Int. J. Med. Sci. 2025; 22(2): 309-317. doi:10.7150/ijms.103341 Full text PDF PubMed PMC

TNF-α Expression and Plasma Cell and Macrophage Numbers in Traumatic Ulcers in a Rat Model Treated by Topical or Systemic Probiotic L. casei Shirota Irma Josefina Savitri, Safira Alif Suprarahardiani, Laila Kamilatu Ulinnuha, Chiquita Prahasanti, I Komang Evan Wijaksana, Rini Devijanti Ridwan, Diah Savitri E, Mohammed Ahmed Aljunaid, Sadatullah Syed, Shahabe Saquib Abullais Int. J. Med. Sci. 2025; 22(2): 318-327. doi:10.7150/ijms.99156 Full text PDF PubMed PMC

Comprehensive multi-omics analysis identifies NUSAP1 as a potential prognostic and immunotherapeutic marker for lung adenocarcinoma Jun Ma, Wenjing Zhu, Yuan Wang, Hongmei Du, Ling Ma, Lisha Liu, Chao Niu, Songlei Li, Kai Zhang, Enwu Yuan Int. J. Med. Sci. 2025; 22(2): 328-340. doi:10.7150/ijms.102331 Full text PDF PubMed PMC

Global trends and risk factors in gastric cancer: a comprehensive analysis of the Global Burden of Disease Study 2021 and multi-omics data Liqun Zhang, Qian Dong, Yuanhe Wang, Xiaoxi Li, Chunning Li, Fang Li, Jingdong Zhang Int. J. Med. Sci. 2025; 22(2): 341-356. doi:10.7150/ijms.104437 Full text PDF PubMed PMC

Comparison of Catheter Ablation in Patients with Paroxysmal Non-valvular Atrial Fibrillation and Heart Failure with Preserved Ejection Fraction Zixi Zhang, Qiuzhen Lin, Cancan Wang, Keke Wu, Yunying Huang, Tao Tu, Zeying Zhang, Hanze Tang, Yichao Xiao, Qiming Liu Int. J. Med. Sci. 2025; 22(2): 371-382. doi:10.7150/ijms.103170 Full text PDF PubMed PMC

A Combination of Punica granatum Fruit Rind and Theobroma cacao Seed Extracts Enhances Sexual Function in Aging Males in a Randomized, Double-blind, Placebo-controlled Study Manoj Kumar Srivastava, Gaurav Singh, Raveendra Ramamurthy Kodur, Amulya Yalamanchi Int. J. Med. Sci. 2025; 22(2): 383-397. doi:10.7150/ijms.99958 Full text PDF PubMed PMC

Enhancement of Interferon-γ Secretion by Lepidium meyenii Extract Supplementation After Exhaustive Endurance Exercise in Healthy Men: A Double-blind, Placebo-controlled Trial Pei-Wei Weng, Yu-Chun Chung, Tso-Ching Lin, Pei-Chia Hsu, Cheng-Tse Yang, Shan Lin, Ming-Ta Yang Int. J. Med. Sci. 2025; 22(2): 398-408. doi:10.7150/ijms.104812 Full text PDF PubMed PMC

Short-term outcomes after robot-assisted versus open radical cystectomy for bladder cancer in patients with diabetes mellitus: an analysis of the United States Nationwide Inpatient Sample of 2005-2018 Cho-Hsing Chung, I-Shen Huang, Wei-Tang Kao Int. J. Med. Sci. 2025; 22(2): 409-416. doi:10.7150/ijms.102667 Full text PDF PubMed PMC

Causal Relationship Between Gluten-Free Diet and Autoimmune-Related Disease Risk: A Comprehensive Mendelian Randomization Study Yi Peng, Chenxi Liu, Wei Liu, Runxin Gan Int. J. Med. Sci. 2025; 22(2): 432-440. doi:10.7150/ijms.104928 Full text PDF PubMed PMC

The Red Cell Distribution Width to Albumin Ratio: A Novel Prognostic Indicator in Hepatitis B Virus-Related Hepatocellular Carcinoma Maoqing Tan, Ruolan You, Danni Cai, Jin Wang, Wei Dai, Rong Yang, Dongliang Li, Huifang Huang Int. J. Med. Sci. 2025; 22(2): 441-450. doi:10.7150/ijms.103125 Full text PDF PubMed PMC

Combined Phacoemulsification, Goniosynechialysis and Ab Interno Trabeculectomy in Primary Angle-closure Glaucoma: Long-term Results Fengrui Yang, Yao Ma, Zhiqiao Liang, Kun Lv, Kangyi Yang, Huijuan Wu Int. J. Med. Sci. 2025; 22(2): 451-459. doi:10.7150/ijms.103795 Full text PDF PubMed PMC

Doublecortin-like kinase 1 promotes stem cell-like properties through the Hippo-YAP pathway in prostate cancer Donggen Jiang, Jun Li, He Ma, Binyuan Yan, Hanqi Lei Int. J. Med. Sci. 2025; 22(2): 460-472. doi:10.7150/ijms.99062 Full text PDF PubMed PMC

Reviews

Comparison of the role of vitamin D in normal organs and those affected by COVID-19 Rajendran Peramaiyan, Josephine Anthony, Sureka Varalakshmi, Ashok Kumar Sekar, Enas M. Ali, Al Hashedi Sallah A, Basem M. Abdallah Int. J. Med. Sci. 2025; 22(2): 240-251. doi:10.7150/ijms.103260 Full text PDF PubMed PMC

Advances on the role of lung macrophages in the pathogenesis of chronic obstructive pulmonary disease in the Era of Single-Cell Genomics Xiaohua Li, Hui Zhang, Xianhong Chi, Weibin Ruan, Xia Meng, Jiehua Deng, Mianluan Pan, Tingting Ma, Jianquan Zhang Int. J. Med. Sci. 2025; 22(2): 298-308. doi:10.7150/ijms.100160 Full text PDF PubMed PMC

Lipoprotein(a) and Atrial Fibrillation: Mechanistic Insights and Therapeutic Approaches Zixi Zhang, Bo Peng, Akedanmu Nuranmubieke, Yangfan Xu, Yan Liu, Tao Tu, Qiuzhen Lin, Cancan Wang, Qiming Liu, Yichao Xiao Int. J. Med. Sci. 2025; 22(2): 357-370. doi:10.7150/ijms.102301 Full text PDF PubMed PMC

Dendritic cell immunometabolism - a potential therapeutic target for allergic diseases Chuang Ouyang, Jiaying Huang, Gonghua Huang, Yanyan Wang Int. J. Med. Sci. 2025; 22(2): 417-431. doi:10.7150/ijms.105532 Full text PDF PubMed PMC

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