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Volume 22 (1); 2025

Research Papers

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A comparative analysis of Marburg virus-infected bat and human models from public high-throughput sequencing data Do Thi Minh Xuan, I-Jeng Yeh, Hsin-Liang Liu, Che-Yu Su, Ching-Chung Ko, Hoang Dang Khoa Ta, Jia-Zhen Jiang, Zhengda Sun, Hung-Yun Lin, Chih-Yang Wang, Meng-Chi Yen Int. J. Med. Sci. 2025; 22(1): 1-16. doi:10.7150/ijms.100696 Full text PDF PubMed PMC

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Ginsenosides, salidroside, and syringin complex exhibits anti-fatigue in exhaustive exercise rats Yung-Chun Wu, Yu Zhi Lian, Hongwei Zhao, Lei Wang, Deshan Ning, Jane C.-J. Chao Int. J. Med. Sci. 2025; 22(1): 17-26. doi:10.7150/ijms.99889 Full text PDF PubMed PMC

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Identification of common diagnostic genes and molecular pathways in endometriosis and systemic lupus erythematosus by machine learning approach and in vitro experiment Pusheng Yang, Yiping Zhu, Yaxin Miao, Tao Wang, Wenwen Liu, Jiaxin Zhang, Beilei Ge, Jing Sun Int. J. Med. Sci. 2025; 22(1): 27-43. doi:10.7150/ijms.101754 Full text PDF PubMed PMC

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Cardiomyopeptide-Regulated PPARγ Expression Plays a Critical Role in Maintaining Mitochondrial Integrity and Preventing Cardiac Ischemia/Reperfusion Injury Zitong Guo, Geng Qian, Xietian Pan, Yuting Zou, Si Chen, Qinglei Zhu, Zhengju Chen Int. J. Med. Sci. 2025; 22(1): 44-52. doi:10.7150/ijms.102763 Full text PDF PubMed PMC

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Identification of JNK-JUN-NCOA axis as a therapeutic target for macrophage ferroptosis in chronic apical periodontitis Yuting Wang, Wenlan Li, Wenli Mu, Abdelrahman Seyam, Yonghui Guan, Yifei Tang, Mingfei Wang, Ying Xin, Xiaomei Guo, Tiezhou Hou, Xiaoyue Guan Int. J. Med. Sci. 2025; 22(1): 53-70. doi:10.7150/ijms.102741 Full text PDF PubMed PMC

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Receptor-Interacting Protein Kinase 3-Mediated Modulation of Endothelial Cell Necroptosis and Mitochondrial Dysfunction through AMPK/Drp1 Signaling Pathway: Insights into the Pathophysiological Mechanisms of Lipopolysaccharide-Induced Acute Lung Injury Zhaoning Zhao, Pingjun Zhu, Yue Lou, Ruoyu Hou, Heqiang Sun, Yingzhen Du, Guogang Xu Int. J. Med. Sci. 2025; 22(1): 71-86. doi:10.7150/ijms.104932 Full text PDF PubMed PMC

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Silencing PCCA Suppresses CRC Growth and Spread by Modulating EMT and M1 Macrophage Polarization Chuyi Zhang, Zhinan Zheng, Huaiming Wang, Ziwei Qi, Ying Wang, Zhunyi Gao, Yuhui Huang, Sanqing Jin Int. J. Med. Sci. 2025; 22(1): 87-100. doi:10.7150/ijms.102046 Full text PDF PubMed PMC

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Cadherin 23 is a prognostic marker of pancreatic cancer and promotes cell viability in floating culture conditions Chaohui Zhen, Peiwei Sun, Rui Liang, Shuang Fei, Xu Chen, Junlin Qian, Baoshi Xu, QiRui Lin, Guojun Yao, Biao Zheng Int. J. Med. Sci. 2025; 22(1): 101-109. doi:10.7150/ijms.98252 Full text PDF PubMed PMC

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Naringenin Mitigates Dasatinib-Induced Kidney Damage by Modulating Antioxidant Defense, Inflammation, and Apoptosis Pathways Khalid Alhazzani, Naif N. Alqarni, Khaldoon Aljerian, Mohammad Raish, Lobna Aljuffali, Samiyah Alshehri, Ahmed Z. Alanazi Int. J. Med. Sci. 2025; 22(1): 110-120. doi:10.7150/ijms.102088 Full text PDF PubMed PMC

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Correlation Among Psoriasis, Iridocyclitis, and Non-alcoholic Fatty Liver Disease: Insights from Mendelian Randomization and Mediation Analysis Shuqin Xu, Long Liu, Chentao Li, Yaoxing Ren, Miaomiao Zhang, Linbiao Xiang, Nan Li, Jiaru Xu, Shuang Bai, Yi Lv Int. J. Med. Sci. 2025; 22(1): 121-131. doi:10.7150/ijms.102369 Full text PDF PubMed PMC

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HPV-Associated Gene Signatures in Bladder Cancer: A Comprehensive Prognostic Model and its Implications in Immunotherapy Zhicheng Tang, Yuxin Qian, Ni Wang, Yinqiu Chen, Haojun Huang, Jiahao Zhang, Hongcheng Luo, Zechao Lu, Zhibiao Li, Zhaohui He, Fucai Tang Int. J. Med. Sci. 2025; 22(1): 140-157. doi:10.7150/ijms.98334 Full text PDF PubMed PMC

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Identification and validation of Novel Estrogen Biosynthesis Biomarkers in Sinonasal Inverted Papilloma Yi-Fang Yang, Sung-Huan Yu, Jia-Bin Liao, Yu-Hsuan Lin Int. J. Med. Sci. 2025; 22(1): 158-169. doi:10.7150/ijms.101753 Full text PDF PubMed PMC

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Analysis of User-Generated Posts on Social Media of Adjuvant Analgesics: A Machine Learning Study Federico Carabot, Carolina Donat-Vargas, Francisco J. Lara-Abelenda, Oscar Fraile- Martínez, Javier Santoma, Cielo Garcia-Montero, Teresa Valadés, Luis Gutierrez-Rojas, MA Martinez-González, Miguel Angel Ortega, Melchor Alvarez-Mon, Miguel Angel Alvarez-Mon Int. J. Med. Sci. 2025; 22(1): 170-178. doi:10.7150/ijms.96981 Full text PDF PubMed PMC

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Investigating the Process of Autoimmune Inner Ear Disease: Unveiling the Intricacies of Pathogenesis and Therapeutic Strategies Mengmeng Wang, Ping Zhang, Qiang Li, Chunyu Kong Int. J. Med. Sci. 2025; 22(1): 179-187. doi:10.7150/ijms.97831 Full text PDF PubMed PMC

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Exploiting Mitochondria by Triggering a Faulty Unfolded Protein Response Leads to Effective Cardioprotection Yang Shen, Xin Gao, Ying Xiang, Hao Zhou, Hang Zhu, Qiang Wu, Jinfeng Liu Int. J. Med. Sci. 2025; 22(1): 188-196. doi:10.7150/ijms.100523 Full text PDF PubMed PMC

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Liver B Cells Promotes MASLD Progression via the Apelin/APLNR System Su Jiang, Jiaxue Lu, Nan Li, Xueqi Bai, Lei Shi, Ziying Tian, Jieyu Zhou, Wenling Zhang Int. J. Med. Sci. 2025; 22(1): 197-208. doi:10.7150/ijms.101492 Full text PDF PubMed PMC

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Enhanced Bone Regeneration by Schwann Cells through Coupling of Osteogenesis and Angiogenesis via β-catenin signaling in a Preclinical Model of Distraction Osteogenesis Xiaoyu Wang, Yifan Yu, Rui Zhang, Jia Xu, Qinglin Kang Int. J. Med. Sci. 2025; 22(1): 209-226. doi:10.7150/ijms.100854 Full text PDF PubMed PMC

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Therapeutic potential of Astragalus-based Eefooton in patients with chronic kidney disease: from clinical to bench study Kuo-Cheng Lu, Ko-Lin Kuo, San-Chiang Wu, Chih-Hui Lin, Cheng-Ju Lin, Yi-Chou Hou, Jin-Shuen Chen Int. J. Med. Sci. 2025; 22(1): 227-239. doi:10.7150/ijms.102280 Full text PDF PubMed PMC

Review

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Research Progress of Regulatory Cell Death in Coronary Microembolization Chen Chang, Wan-Zhong Huang, Ru-Ping Cai, Li-Rong Mo, Qiang Wu, Qiang Su Int. J. Med. Sci. 2025; 22(1): 132-139. doi:10.7150/ijms.105295 Full text PDF PubMed PMC

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