International Journal of Medical Sciences

22 August 2014

ISSN 1449-1907 News feeds of published articles

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Editor-in-Chief: Dennis D. Taub, Ph.D.
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  • Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
  • Full texts of articles appear in PubMed Central, Europe PMC, and PMC Canada.
  • High visibility of articles over the Internet.
  • (For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement.
  • This Journal is ranked very well according to SCImago in the area of Medicine ...details

Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details

International Journal of Medical Sciences Cover Page

Short Research Communication
Heterogeneity of Osteosarcoma Cell Lines Led to Variable Responses in Reprogramming
Pei Feng Choong, Hui Xin Teh, Hoon Koon Teoh, Han Kiat Ong, Kong Bung Choo, Shigeki Sugii, Soon Keng Cheong, Tunku Kamarul
Int. J. Med. Sci. 2014; 11(11): 1154-1160. doi:10.7150/ijms.8281
[Abstract] [Full text] [PDF]

Research Paper
Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients
Haidar A. Shamran, Subah J. Hamza, Nahi Y. Yaseen, Ahmad A. Al-Juboory, Dennis D Taub, Robert L. Price, Mitzi Nagarkatti, Prakash S. Nagarkatti, Udai P. Singh
Int. J. Med. Sci. 2014; 11(11): 1147-1153. doi:10.7150/ijms.9412
[Abstract] [Full text] [PDF]

Research Paper
P Wave Dispersion and QT Dispersion in Adult Turkish Migrants with Familial Mediterranean Fever Living in Germany
Arnd Giese, Ahmet Örnek, Mustafa Kurucay, Kaffer Kara, Helmut Wittkowski, Faekah Gohar, Bjoern A. Menge, Wolfgang E. Schmidt, Christoph Zeidler
Int. J. Med. Sci. 2014; 11(11): 1140-1146. doi:10.7150/ijms.9444
[Abstract] [Full text] [PDF]

Research Paper
In vitro Protease Inhibition and Cytotoxicity of Aspergillus fumigatus Biomolecules Secreted under Long-Term Aerated Conditions
Valentina S. Arsic Arsenijevic, Marina G. Pekmezovic, Katarina M. Rajkovic, Berislav P. Vekic, Aleksandra M. Barac, Suzana Tasic-Otasevic, Ljubica Dj. Petkovic
Int. J. Med. Sci. 2014; 11(11): 1133-1139. doi:10.7150/ijms.8325
[Abstract] [Full text] [PDF]

Short Research Communication
Relationship between European Mitochondrial Haplogroups and Chronic Renal Allograft Rejection in Patients with Kidney Transplant
María Angeles JIMÉNEZ-SOUSA, Eduardo TAMAYO, María GUZMÁN-FULGENCIO, Amanda FERNÁNDEZ-RODRÍGUEZ, María HEREDIA-RODRIGUEZ, Mónica GARCÍA-ÁLVAREZ, Jesús F BERMEJO-MARTIN, Daniel PINEDA-TENOR, Patricia RUIZ-GRANADO, Elisa ALVAREZ-FUENTE, Esther GÓMEZ-SANCHEZ, José I GÓMEZ-HERRERAS, Salvador RESINO
Int. J. Med. Sci. 2014; 11(11): 1129-1132. doi:10.7150/ijms.9487
[Abstract] [Full text] [PDF]

Research Paper
Cultured Human Periosteal-Derived Cells Have Inducible Adipogenic Activity and Can Also Differentiate Into Osteoblasts in a Perioxisome Proliferator-Activated Receptor-Mediated Fashion
Young-Sool Hah, Hyun-Ho Joo, Young-Hoon Kang, Bong-Wook Park, Sun-Chul Hwang, Jong-Woo Kim, Iel-Yong Sung, Gyu-Jin Rho, Dong Kyun Woo, June-Ho Byun
Int. J. Med. Sci. 2014; 11(11): 1116-1128. doi:10.7150/ijms.9611
[Abstract] [Full text] [PDF]

Research Paper
Levocarnitine Protects H9c2 Rat Cardiomyocytes from H2O2-induced Mitochondrial Dysfunction and Apoptosis
Cui-Ying Mao, Hai-Bin Lu, Ning Kong, Jia-Yu Li, Miao Liu, Chun-Yan Yang, Ping Yang
Int. J. Med. Sci. 2014; 11(11): 1107-1115. doi:10.7150/ijms.9153
[Abstract] [Full text] [PDF]

Research Paper
Comparison the Prognostic Value of Galectin-3 and Serum Markers of Cardiac Extracellular Matrix Turnover in Patients with Chronic Systolic Heart Failure
Yi-Yao Chang, Aaron Chen, Xue-Ming Wu, Tse-Pin Hsu, Li-Yu Daisy Liu, Yenh-Hsein Chen, Yen-Wen Wu, Hung-Ju Lin, Ron-Bin Hsu, Chi-Ming Lee, Shoei-Shen Wang, Men-Tzung Lo, Ming-Fong Chen, Yen-Hung Lin
Int. J. Med. Sci. 2014; 11(11): 1098-1106. doi:10.7150/ijms.8083
[Abstract] [Full text] [PDF]

Research Paper
AKR1C3 Overexpression Mediates Methotrexate Resistance in Choriocarcinoma Cells
Jing Zhao, Yang Xiang, Changji Xiao, Peng Guo, Dan Wang, Ying Liu, Yun Shen
Int. J. Med. Sci. 2014; 11(11): 1089-1097. doi:10.7150/ijms.9239
[Abstract] [Full text] [PDF]

Research Paper
Laparoscopic Reconstructive Surgery is Superior to Vaginal Reconstruction in the Pelvic Organ Prolapse
Young-Han Park, Seong Cheon Yang, Sung Taek Park, Sung Ho Park, Hong Bae Kim
Int. J. Med. Sci. 2014; 11(11): 1082-1088. doi:10.7150/ijms.9027
[Abstract] [Full text] [PDF]

Research Paper
Astragaloside IV Alleviates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats
Anwen Shao, Songxue Guo, Sheng Tu, Al-baadani Ammar, Junjia Tang, Yuan Hong, Haijian Wu, Jianmin Zhang
Int. J. Med. Sci. 2014; 11(10): 1073-1081. doi:10.7150/ijms.9282
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Bone Morphogenetic Protein-9 Induces PDLSCs Osteogenic Differentiation through the ERK and p38 Signal Pathways
Guo Ye, Conghua Li, Xuerong Xiang, Chu Chen, Ruyi Zhang, Xia Yang, Xuesong Yu, Jinhua Wang, Lan Wang, Qiong Shi, Yaguang Weng
Int. J. Med. Sci. 2014; 11(10): 1065-1072. doi:10.7150/ijms.8473
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Opposite Effects of Bone Marrow-Derived Cells Transplantation in MPTP-rat Model of Parkinson's Disease: A Comparison Study of Mononuclear and Mesenchymal Stem Cells
Caroline Santos Capitelli, Carolina Salomão Lopes, Angélica Cristina Alves, Janaína Barbiero, Lucas Felipe Oliveira, Valdo José Dias da Silva, Maria Aparecida Barbato Frazão Vital
Int. J. Med. Sci. 2014; 11(10): 1049-1064. doi:10.7150/ijms.8182
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review
Research Progress on Vertebrobasilar Dolichoectasia
Yong-Jie Yuan, Kan Xu, Qi Luo, Jin-Lu Yu
Int. J. Med. Sci. 2014; 11(10): 1039-1048. doi:10.7150/ijms.8566
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Three-Dimensional Culture Environment Increases the Efficacy of Platelet Rich Plasma Releasate in Prompting Skin Fibroblast Differentiation and Extracellular Matrix Formation
Hussin A. Rothan, Ivan Djordjevic, Hirbod Bahrani, Mohammadjavad Paydar, Fatimah Ibrahim, Noorsaadah Abd Rahmanh, Rohana Yusof
Int. J. Med. Sci. 2014; 11(10): 1029-1038. doi:10.7150/ijms.8895
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Activated Hair Follicle Stem Cells and Wnt/β-catenin Signaling Involve in Pathnogenesis of Sebaceous Neoplasms
Weiming Qiu, Mingxing Lei, Jin Li, Ning Wang, Xiaohua Lian
Int. J. Med. Sci. 2014; 11(10): 1022-1028. doi:10.7150/ijms.8383
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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