International Journal of Medical Sciences

Impact factor
2.284

23 July 2018

ISSN 1449-1907 News feeds of published articles

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Theranostics

Journal of Cancer

International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Oncomedicine

Journal of Biomedicine

Nanotheranostics

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Impact factor is 2.284 according to 2018 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Systematic Analysis of Differential Expression Profile in Rheumatoid Arthritis Chondrocytes Using Next-Generation Sequencing and Bioinformatics Approaches
Yi-Jen Chen, Wei-An Chang, Ling-Yu Wu, Ya-Ling Hsu, Chia-Hsin Chen, Po-Lin Kuo
Int. J. Med. Sci. 2018; 15(11): 1129-1142. doi:10.7150/ijms.27056
[Abstract] [Full text] [PDF]

Research Paper
Drug repurposing: Ibrutinib exhibits immunosuppressive potential in organ transplantation
Qing Zhang, Jicheng Chen, Hanchao Gao, Song Zhang, Chengjiang Zhao, Cuibing Zhou, Chengjun Wang, Yang Li, Zhiming Cai, Lisha Mou
Int. J. Med. Sci. 2018; 15(11): 1118-1128. doi:10.7150/ijms.24460
[Abstract] [Full text] [PDF]

Research Paper
Urinary Orosomucoid A Potential Marker Of Inflammation In Psoriasis
Péter Kustán, Tamás Kőszegi, Attila Miseta, Iván Péter, Zénó Ajtay, István Kiss, Balázs Németh
Int. J. Med. Sci. 2018; 15(11): 1113-1117. doi:10.7150/ijms.25687
[Abstract] [Full text] [PDF]

Research Paper
Effect of laser therapy on expression of angio- and fibrogenic factors, and cytokine concentrations during the healing process of human pressure ulcers
Jakub Taradaj, Barbara Shay, Robert Dymarek, Mirosław Sopel, Karolina Walewicz, Dimitri Beeckman, Lisette Schoonhoven, Amit Gefen, Joanna Rosińczuk
Int. J. Med. Sci. 2018; 15(11): 1105-1112. doi:10.7150/ijms.25651
[Abstract] [Full text] [PDF]

Research Paper
The Relationship of Serum Antigen-Specific and Total Immunoglobulin E with Adult Cardiovascular Diseases
Zhiyan Xu, Tao Wang, Xiaoxiao Guo, Yao Li, Yi Hu, Chao Ma, Jing Wang
Int. J. Med. Sci. 2018; 15(11): 1098-1104. doi:10.7150/ijms.25857
[Abstract] [Full text] [PDF]

Research Paper
Study on the classification of Descemet membrane detachment after cataract surgery with AS-OCT
Ping Guo, Yujin Pan, Yuan Zhang, Sean Tighe, Yingting Zhu, Ming Li, Xiaoli Shen, Baotao Lin, Binghong Pan, Xinhua Liu, Hongbo Cheng
Int. J. Med. Sci. 2018; 15(11): 1092-1097. doi:10.7150/ijms.26972
[Abstract] [Full text] [PDF]

Research Paper
Melatonin alleviates oxidative stress-inhibited osteogenesis of human bone marrow-derived mesenchymal stem cells through AMPK activation
Sooho Lee, Nhu Huynh Le, Dongchul Kang
Int. J. Med. Sci. 2018; 15(10): 1083-1091. doi:10.7150/ijms.26314
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Clinical and Basic Evaluation of the Prognostic Value of Uric Acid in Traumatic Brain Injury
Han Liu, Junchi He, Jianjun Zhong, Hongrong Zhang, Zhaosi Zhang, Liu Liu, Zhijian Huang, Yue Wu, Li Jiang, Zongduo Guo, Rui Xu, Weina Chai, Gang Huo, Xiaochuan Sun, Chongjie Cheng
Int. J. Med. Sci. 2018; 15(10): 1072-1082. doi:10.7150/ijms.25799
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Rac1 promotes the survival of H9c2 cells during serum deficiency targeting JNK/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways
Jinlong Zhao, Qiqiang Jie, Gang Li, Yong Li, Baoxin Liu, Hongqiang Li, Jiachen Luo, Xiaoming Qin, Zhiqiang Li, Yidong Wei
Int. J. Med. Sci. 2018; 15(10): 1062-1071. doi:10.7150/ijms.25527
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Migration of mesenchymal stem cells to tumor xenograft models and in vitro drug delivery by doxorubicin
Senthilkumar Kalimuthu, Liya Zhu, Ji Min Oh, Prakash Gangadaran, Ho Won Lee, Se hwan Baek, Ramya Lakshmi Rajendran, Arunnehru Gopal, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn
Int. J. Med. Sci. 2018; 15(10): 1051-1061. doi:10.7150/ijms.25760
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review
A Review on the Effects of Bisphenol A and Its Derivatives on Skeletal Health
Kok-Yong Chin, Kok-Lun Pang, Wun Fui Mark-Lee
Int. J. Med. Sci. 2018; 15(10): 1043-1050. doi:10.7150/ijms.25634
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects
Wen-Chang Wang, Yen-Feng Chiu, Ren-Hua Chung, Chii-Min Hwu, I-Te Lee, Chien-Hsing Lee, Yi-Cheng Chang, Kuan-Yi Hung, Thomas Quertermous, Yii-Der I. Chen, Chao A. Hsiung
Int. J. Med. Sci. 2018; 15(10): 1035-1042. doi:10.7150/ijms.25742
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
The Combination Of Weak Expression Of PRDX4 And Very High MIB-1 Labelling Index Independently Predicts Shorter Disease-free Survival In Stage I Lung Adenocarcinoma
Akihiro Shioya, Xin Guo, Nozomu Motono, Seiya Mizuguchi, Nozomu Kurose, Satoko Nakada, Akane Aikawa, Yoshitaka Ikeda, Hidetaka Uramoto, Sohsuke Yamada
Int. J. Med. Sci. 2018; 15(10): 1025-1034. doi:10.7150/ijms.25734
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Trehalose inhibits H2O2-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activation
Zhijie Gao, Helei Wang, Bo Zhang, Xuemei Wu, Yanfeng Zhang, Pengfei Ge, Guangfan Chi, Jianmin Liang
Int. J. Med. Sci. 2018; 15(10): 1014-1024. doi:10.7150/ijms.25656
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Relationship of genetic variant distributions of WW domain-containing oxidoreductase gene with uterine cervical cancer
Yu-Hsiang Lin, Yi-Hsuan Hsiao, Wen-Jun Wu, Shun-Fa Yang, Chun-Fang Hsu, Yu-Ting Kang, Po-Hui Wang
Int. J. Med. Sci. 2018; 15(10): 1005-1013. doi:10.7150/ijms.25553
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
AKAP11 gene polymorphism is associated with bone mass measured by quantitative ultrasound in young adults
María Correa-Rodríguez, Jacqueline Schmidt Rio-Valle, Blanca Rueda-Medina
Int. J. Med. Sci. 2018; 15(10): 999-1004. doi:10.7150/ijms.25369
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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