International Journal of Medical Sciences
Official Impact Factor

1 July 2016

ISSN 1449-1907 News feeds of published articles

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new Impact factor is 2.232 according to 2016 release of Journal Citation ReportsĀ®. Congratulations!

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Therapeutic Progress in Treating Vertebral Dissecting Aneurysms Involving the Posterior Inferior Cerebellar Artery
Lei Shi, Kan Xu, Xiaofeng Sun, Jinlu Yu
Int. J. Med. Sci. 2016; 13(7): 540-555. doi:10.7150/ijms.15233
[Abstract] [Full text] [PDF]

Research Paper
Expression of SRSF3 is Correlated with Carcinogenesis and Progression of Oral Squamous Cell Carcinoma
Liu Peiqi, Guo Zhaozhong, Yin Yaotian, Jia Jun, Guo Jihua, Jia Rong
Int. J. Med. Sci. 2016; 13(7): 533-539. doi:10.7150/ijms.14871
[Abstract] [Full text] [PDF]

Research Paper
Evaluation of the Effectiveness of Peritoneal Adhesion Prevention Devices in a Rat Model
D Poehnert, L Grethe, L Maegel, D Jonigk, T Lippmann, A Kaltenborn, H Schrem, J Klempnauer, M Winny
Int. J. Med. Sci. 2016; 13(7): 524-532. doi:10.7150/ijms.15167
[Abstract] [Full text] [PDF]

Research Paper
Effects of LG268 on Cell Proliferation and Apoptosis of NB4 Cells
Ting Xu, Liang Zhong, Liugen Gan, Chunlan Xiao, Zhiling Shan, Rong Yang, Hao Song, Liu Li, Beizhong Liu
Int. J. Med. Sci. 2016; 13(7): 517-523. doi:10.7150/ijms.15507
[Abstract] [Full text] [PDF]

Research Paper
A Mechanism for the Temporal Potentiation of Genipin to the Cytotoxicity of Cisplatin in Colon Cancer Cells
Ruihua Wang, KC MoYung, YJ Zhao, Karen Poon
Int. J. Med. Sci. 2016; 13(7): 507-516. doi:10.7150/ijms.15449
[Abstract] [Full text] [PDF]

Research Paper
Migration and Differentiation of GFP-transplanted Bone Marrow-derived Cells into Experimentally Induced Periodontal Polyp in Mice
Saeka Matsuda, Masahito Shoumura, Naoto Osuga, Hidetsugu Tsujigiwa, Keisuke Nakano, Norimasa Okafuji, Takanaga Ochiai, Hiromasa Hasegawa, Toshiyuki Kawakami
Int. J. Med. Sci. 2016; 13(7): 500-506. doi:10.7150/ijms.15671
[Abstract] [Full text] [PDF]

Research Paper
Interdependencies among Selected Pro-Inflammatory Markers of Endothelial Dysfunction, C-Peptide, Anti-Inflammatory Interleukin-10 and Glucose Metabolism Disturbance in Obese Women
Joanna Janowska, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz, Elżbieta Semik-Grabarczyk, Barbara Zahorska-Markiewicz
Int. J. Med. Sci. 2016; 13(7): 490-499. doi:10.7150/ijms.14110
[Abstract] [Full text] [PDF]

Research Paper
A Formulation Study of 5-Aminolevulinic Encapsulated in DPPC Liposomes in Melanoma Treatment
Ming-Wei Lin, Yaw-Bin Huang, Chun-Lin Chen, Pao-Chu Wu, Chien-Ying Chou, Ping-Ching Wu, Shih-Ya Hung
Int. J. Med. Sci. 2016; 13(7): 483-489. doi:10.7150/ijms.15411
[Abstract] [Full text] [PDF]

Research Paper
Thrombus Aspirated from Patients with ST-Elevation Myocardial Infarction: Association between 3-Nitrotyrosine and Inflammatory Markers - Insights from ARTERIA Study
Alberto Dominguez-Rodriguez, Pedro Abreu-Gonzalez, Luciano Consuegra-Sanchez, Pablo Avanzas, Alejandro Sanchez-Grande, Pablo Conesa-Zamora
Int. J. Med. Sci. 2016; 13(7): 477-482. doi:10.7150/ijms.15463
[Abstract] [Full text] [PDF]

Research Paper
Efficacy of Honeycomb TCP-induced Microenvironment on Bone Tissue Regeneration in Craniofacial Area
Satoko Watanabe, Kiyofumi Takabatake, Hidetsugu Tsujigiwa, Toshiyuki Watanabe, Eijiro Tokuyama, Satoshi Ito, Hitoshi Nagatsuka, Yoshihiro Kimata
Int. J. Med. Sci. 2016; 13(6): 466-476. doi:10.7150/ijms.15560
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Differential microRNA Profiles Predict Diabetic Nephropathy Progression in Taiwan
Hung-Yu Chien, Chang-Yi Chen, Yen-Hui Chiu, Yi-Chun Lin, Wan-Chun Li
Int. J. Med. Sci. 2016; 13(6): 457-465. doi:10.7150/ijms.15548
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
The Association of -429T>C and -374T>A Polymorphisms in the RAGE Gene with Polycystic Ovary Syndrome
Jung-Hyun Park, Lan Li, Jin-Woo Choi, Kwang-Hyun Baek
Int. J. Med. Sci. 2016; 13(6): 451-456. doi:10.7150/ijms.15389
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Longitudinal Associations between Triglycerides and Metabolic Syndrome Components in a Beijing Adult Population, 2007-2012
Li-Xin Tao, Kun Yang, Xiang-Tong Liu, Kai Cao, Hui-Ping Zhu, Yan-Xia Luo, Jin Guo, Li-Juan Wu, Xia Li, Xiu-Hua Guo
Int. J. Med. Sci. 2016; 13(6): 445-450. doi:10.7150/ijms.14256
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Gender Related Survival Differences in ST-Elevation Myocardial Infarction Patients Treated with Primary PCI
Vojko Kanic, Maja Vollrath, Franjo Husam Naji, Andreja Sinkovic
Int. J. Med. Sci. 2016; 13(6): 440-444. doi:10.7150/ijms.15214
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Study and Therapeutic Progress on Intracranial Serpentine Aneurysms
Kan Xu, Tiecheng Yu, Yunbao Guo, Jinlu Yu
Int. J. Med. Sci. 2016; 13(6): 432-439. doi:10.7150/ijms.14934
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Detection of Human Papillomavirus 16-Specific IgG and IgM Antibodies in Patient Sera: A Potential Indicator of Oral Squamous Cell Carcinoma Risk Factor
Jesinda P. Kerishnan, Subash C.B. Gopinath, Sia Bik Kai, Thean-Hock Tang, Helen Lee-Ching Ng, Zainal Ariff Abdul Rahman, Uda Hashim, Yeng Chen
Int. J. Med. Sci. 2016; 13(6): 424-431. doi:10.7150/ijms.14475
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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