International Journal of Medical Sciences

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19 December 2018

ISSN 1449-1907 News feeds of published articles

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Impact factor is 2.284 according to 2018 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Deduction of Novel Genes Potentially Involved in Upper Tract Urothelial Carcinoma Using Next-Generation Sequencing and Bioinformatics Approaches
Hsiang-Ying Lee, Yi-Jen Chen, Ching-Chia Li, Wei-Ming Li, Ya-Ling Hsu, Hsin-Chih Yeh, Hung-Lung Ke, Chun-Nung Huang, Chien-Feng Li, Wen-Jeng Wu, Po-Lin Kuo
Int. J. Med. Sci. 2019; 16(1): 93-105. doi:10.7150/ijms.29560
[Abstract] [Full text] [PDF]

Research Paper
Proteomic Study of a Parkinson's Disease Model of Undifferentiated SH-SY5Y Cells Induced by a Proteasome Inhibitor
Huiyi Jiang1, Yang Yu, Shicheng Liu, Mingqin Zhu, Xiang Dong, Jinying Wu, Zhou Zhang, Ming Zhang, Ying Zhang
Int. J. Med. Sci. 2019; 16(1): 84-92. doi:10.7150/ijms.28595
[Abstract] [Full text] [PDF]

Research Paper
Ultrasound/Elastography techniques, lipidomic and blood markers compared to Magnetic Resonance Imaging in non-alcoholic fatty liver disease adults
Irene Cantero, Mariana Elorz, Itziar Abete, Bertha Araceli Marin, Jose Ignacio Herrero, Jose Ignacio Monreal, Alberto Benito, Jorge Quiroga, Ana Martínez, Mª Pilar Huarte, Juan Isidro Uriz-Otano, Josep Antoni Tur, John Kearney, J. Alfredo Martinez, M. Angeles Zulet
Int. J. Med. Sci. 2019; 16(1): 75-83. doi:10.7150/ijms.28044
[Abstract] [Full text] [PDF]

Research Paper
MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer
Lichao Sun, Hebao Yuan, Joseph Burnett, Mari Gasparyan, Yuan Zhang, Feng Zhang, Zhihua Yang, Yuliang Ran, Duxin Sun
Int. J. Med. Sci. 2019; 16(1): 68-74. doi:10.7150/ijms.27595
[Abstract] [Full text] [PDF]

Research Paper
A Novel Model for Studying Voltage-Gated Ion Channel Gene Expression during Reversible Ischemic Stroke
Yun-Shen Tai, Shih-Chieh Yang, Yi-Chun Hsieh, Yaw-Bin Huang, Pao-Chu Wu, Ming-Jun Tsai, Yi-Hung Tsai, Ming-Wei Lin
Int. J. Med. Sci. 2019; 16(1): 60-67. doi:10.7150/ijms.27442
[Abstract] [Full text] [PDF]

Research Paper
LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1
Xinke Wang, Qiuhua Lai, Juan He, Qingyuan Li, Jian Ding, Zhixian Lan, Chuncai Gu, Qun Yan, Yuxin Fang, Xinmei Zhao, Side Liu
Int. J. Med. Sci. 2019; 16(1): 51-59. doi:10.7150/ijms.27359
[Abstract] [Full text] [PDF]

Research Paper
Extravascular compared to Intravascular Femoral Closure is Associated with Less Bleeding and Similar MACE after Percutaneous Coronary Intervention
Seung-Hyun Kim, Michael Behnes, Sebastian Baron, Tetyana Shchetynska-Marinova, Melike Uensal, Kambis Mashayekhi, Ursula Hoffmann, Martin Borggrefe, Ibrahim Akin
Int. J. Med. Sci. 2019; 16(1): 43-50. doi:10.7150/ijms.29253
[Abstract] [Full text] [PDF]

Research Paper
Complete Disaggregation of MCF-7-derived Breast Tumour Spheroids with Very Low Concentrations of α-Mangostin Loaded in CD44 Thioaptamer-tagged Nanoparticles
Francesca Bonafè, Claudia Pazzini, Silvia Marchionni, Carlo Guarnieri, Claudio Muscari
Int. J. Med. Sci. 2019; 16(1): 33-42. doi:10.7150/ijms.28135
[Abstract] [Full text] [PDF]

Research Paper
Nitrogen Containing Bisphosphonates Impair the Release of Bone Homeostasis Mediators and Matrix Production by Human Primary Pre-Osteoblasts
Chiara Giannasi, Stefania Niada, Davide Farronato, Giovanni Lombardi, Barbara Manfredi, Giampietro Farronato, Anna Teresa Brini
Int. J. Med. Sci. 2019; 16(1): 23-32. doi:10.7150/ijms.27470
[Abstract] [Full text] [PDF]

Research Paper
Switching Lamivudine with Adefovir Dipivoxil Combination Therapy to Entecavir Monotherapy Provides Better Viral Suppression and Kidney Safety
Jiang-Shan Lian, Xiao-Lin Zhang, Ying-Feng Lu, Jian-Yang Chen, Yi-Min Zhang, Hong-Yu Jia, Zhe Zhang, Yi-Da Yang
Int. J. Med. Sci. 2019; 16(1): 17-22. doi:10.7150/ijms.28700
[Abstract] [Full text] [PDF]

Research Paper
Protective Effect of Baicalein on Oxidative Stress-induced DNA Damage and Apoptosis in RT4-D6P2T Schwann Cells
Cheol Park, Eun Ok Choi, Gi-Young Kim, Hye-Jin Hwang, Byung Woo Kim, Young Hyun Yoo, Hwan Tae Park, Yung Hyun Choi
Int. J. Med. Sci. 2019; 16(1): 8-16. doi:10.7150/ijms.29692
[Abstract] [Full text] [PDF]

Research Paper
Influence of Glucose Dosage in Parenteral Nutrition on Body Thiamine Levels in Rats
Daisuke Harada, Mitsuo Nakayama
Int. J. Med. Sci. 2019; 16(1): 1-7. doi:10.7150/ijms.28756
[Abstract] [Full text] [PDF]

Research Paper
No Evidence for Lower Levels of Serum Vitamin D in the Presence of Hepatic Steatosis. A Study on the Portuguese General Population
Jorge Leitão, Sofia Carvalhana, Ana Paula Silva, Francisco Velasco, Isabel Medeiros, Ana Catarina Alves, Mafalda Bourbon, Bárbara Oliveiros, Armando Carvalho, Helena Cortez-Pinto
Int. J. Med. Sci. 2018; 15(14): 1778-1786. doi:10.7150/ijms.26586
[Abstract] [Full text] [PDF]

Research Paper
Development of a Model for the Prediction of Treatment Response of Uterine Leiomyomas after Uterine Artery Embolization
Youn-Jee Chung, So-Yeon Kang, Ho Jong Chun, Sung Eun Rha, Hyun Hee Cho, Jang Heub Kim, Mee-Ran Kim
Int. J. Med. Sci. 2018; 15(14): 1771-1777. doi:10.7150/ijms.28687
[Abstract] [Full text] [PDF]

Research Paper
Effectiveness of Eccentric Exercise and a Vibration or Cryotherapy Program in Enhancing Rectus Abdominis Muscle Thickness and Inter-Rectus Distance in Patients with Chronic Mid-Portion Achilles Tendinopathy: A Randomized Clinical Trial
Carlos Romero-Morales, Pedro Javier Martín-Llantino, César Calvo-Lobo, Hector Beltran-Alacreu, Daniel López-López, Rubén Sánchez-Gómez, David Rodríguez-Sanz
Int. J. Med. Sci. 2018; 15(14): 1764-1770. doi:10.7150/ijms.28656
[Abstract] [Full text] [PDF]

Research Paper
An Increased Neutrophil-to-Lymphocyte Ratio Predicts Incomplete Response to Therapy in Differentiated Thyroid Cancer
Fang Lee, Po-Sheng Yang, Ming-Nan Chien, Jie-Jen Lee, Ching-Hsiang Leung, Shih-Ping Cheng
Int. J. Med. Sci. 2018; 15(14): 1757-1763. doi:10.7150/ijms.28498
[Abstract] [Full text] [PDF]

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