International Journal of Medical Sciences

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25 April 2019

ISSN 1449-1907 News feeds of published articles

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Journal of Genomics



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Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of these polysaccharide-rich extracts in LoVo and HT-29 human colon cancer cells. The in vitro effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Moreover, the effect on anchorage independent-cell growth was also determined. Our results showed that TV and GF extracts did inhibit human colon cell proliferation and induce cytotoxicity.. ...details
A number of biomaterials have been developed, some of which already enjoy widespread clinic use. We have devised a new honeycomb tricalcium phosphate (TCP) containing through-and-through holes of various diameters to control cartilage and bone formation. However, the way in which the geometric structure of the honeycomb TCP controls cartilage and bone tissue formation separately remains unknown. In addition, an association has been reported between bone formation and angiogenesis. Therefore, in the present study, we investigated the relationship between angiogenesis and various hole diameters in our honeycomb TCP over time in a rat ectopic hard tissue formation model.. ...details

Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste and smell, dental sensitivity.

The aim of this observational study was to investigate the prevalence of TMD symptoms and signs as well as oral implications in patients with Early Rheumatoid Arthritis (ERA), that is a RA diagnosed within 12 months, compared with a control group.

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Research Paper
Effects of Long Form of CAPON Overexpression on Glioma Cell Proliferation are Dependent on AKT/mTOR/P53 Signaling
Dong Liang, Yunnong Song, Guangwei Fan, Daofei Ji, Tong Zhang, Er Nie, Xuejiao Liu, Jun Liang, Rutong Yu, Shangfeng Gao
Int. J. Med. Sci. 2019; 16(4): 614-622. doi:10.7150/ijms.31579
[Abstract] [Full text] [PDF]

Research Paper
Falls rate increase and foot dorsal flexion limitations are exhibited in patients who suffer from asthma: A novel case-control study
César Calvo-Lobo, Roi Painceira-Villar, Vanesa García-Paz, Ricardo Becerro-de-Bengoa-Vallejo, Marta Elena Losa-Iglesias, Pedro V. Munuera-Martínez, Daniel López-López
Int. J. Med. Sci. 2019; 16(4): 607-613. doi:10.7150/ijms.32105
[Abstract] [Full text] [PDF]

Research Paper
Effect of Sucrier Banana Peel Extracts on Inhibition of Melanogenesis through the ERK Signaling Pathway
Naphichaya Phacharapiyangkul, Krit Thirapanmethee, Khanit Sa-ngiamsuntorn, Uraiwan Panich, Che-Hsin Lee, Mullika Chomnawang
Int. J. Med. Sci. 2019; 16(4): 602-606. doi:10.7150/ijms.32137
[Abstract] [Full text] [PDF]

Research Paper
Suppressive Effects of Aspirin for Postthoracotomy Pleural Adhesion in Rats
Shunta Ishihara, Kazuhiro Ito, Satoru Okada, Masanori Shimomura, Junichi Shimada, Tadanori Yamaguchi, Masayoshi Inoue
Int. J. Med. Sci. 2019; 16(4): 593-601. doi:10.7150/ijms.32632
[Abstract] [Full text] [PDF]

Research Paper
Expression of Chosen Carcinoembryonic-Related Cell Adhesion Molecules in Pancreatic Intraepithelial Neoplasia (PanIN) Associated with Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma (PDAC)
Justyna Zińczuk, Konrad Zaręba, Wioletta Romaniuk, Dorota Kamińska, Marcin Nizioł, Magdalena Baszun, Bogusław Kędra, Katarzyna Guzińska-Ustymowicz, Anna Pryczynicz
Int. J. Med. Sci. 2019; 16(4): 583-592. doi:10.7150/ijms.32751
[Abstract] [Full text] [PDF]

Research Paper
Decreased DNA methyltransferases expression is associated with coronary artery lesion formation in Kawasaki disease
Ying-Hsien Huang, Kuang-Den Chen, Mao-Hung Lo, Xin-Yuan Cai, Ling-Sai Chang, Yu-Hsia Kuo, Wei-Dong Huang, Ho-Chang Kuo
Int. J. Med. Sci. 2019; 16(4): 576-582. doi:10.7150/ijms.32773
[Abstract] [Full text] [PDF]

Research Paper
Matrigel Scaffolding Enhances BMP9-induced Bone Formation in Dental Follicle Stem/Precursor Cells
Tiwei Fu, Panpan Liang, Jinlin Song, jinhua Wang, Pengfei Zhou, Yinhong Tang, Jing Li, Enyi Huang
Int. J. Med. Sci. 2019; 16(4): 567-575. doi:10.7150/ijms.30801
[Abstract] [Full text] [PDF]

Research Paper
Clinical Significance of BCL2, C-MYC, and BCL6 Genetic Abnormalities, Epstein-Barr Virus Infection, CD5 Protein Expression, Germinal Center B Cell/Non-Germinal Center B-Cell Subtypes, Co-expression of MYC/BCL2 Proteins and Co-expression of MYC/BCL2/BCL6 Proteins in Diffuse Large B-Cell Lymphoma: A Clinical and Pathological Correlation Study of 120 Patients
Choo-Yuen Ting, Kian-Meng Chang, Jew-Win Kuan, Jameela Sathar, Lee-Ping Chew, Oy-Leng Jacqueline Wong, Yusri Yusuf, Lily Wong, Ahmad Toha Samsudin, Mohd Nurjaya Bin Mohd Pana, Suk-Kam Lee, Navarasi S. Raja Gopal, Rita Puri, Tee-Chuan Ong, Samsol Kamal Bahari, Ai-Sim Goh, Ching- Soon Teoh
Int. J. Med. Sci. 2019; 16(4): 556-566. doi:10.7150/ijms.27610
[Abstract] [Full text] [PDF]

MALAT1 as a Diagnostic and Therapeutic Target in Diabetes-Related Complications: A Promising Long-Noncoding RNA
Leila Elmi Abdulle, Ji-long Hao, Om Prakash Pant, Xiu-fen Liu, Dan-dan Zhou, Ying Gao, Abhishek Suwal, Cheng-wei Lu
Int. J. Med. Sci. 2019; 16(4): 548-555. doi:10.7150/ijms.30097
[Abstract] [Full text] [PDF]

Research Paper
Microarray Analysis of Long Non-Coding RNAs and Messenger RNAs in a Mouse Model of Oxygen-Induced Retinopathy
Lusi Zhang, Xiaolin Fu, Huilan Zeng, Jiang-Hui Wang, Yingqian Peng, Han Zhao, Jingling Zou, Liwei Zhang, Yun Li, Shigeo Yoshida, Yedi Zhou
Int. J. Med. Sci. 2019; 16(4): 537-547. doi:10.7150/ijms.31274
[Abstract] [Full text] [PDF]

Research Paper
Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells
Chengbo Wang, Keyan Li, Yingli Men, Cong Ding, Juan Du, Taotao Liang, Zhenyu Ji, Lixiang Chen, Ting Wang, Qiaozhen Kang
Int. J. Med. Sci. 2019; 16(4): 529-536. doi:10.7150/ijms.27401
[Abstract] [Full text] [PDF]

Research Paper
Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma
Ann Marie Mongan, Niamh Lynam-Lennon, Suzanne L Doyle, Rory Casey, Eibhlin Carr, Aoife Cannon, Melissa J Conroy, Graham P Pidgeon, Lorraine Brennan, Joanne Lysaght, John V. Reynolds, Jacintha O'Sullivan
Int. J. Med. Sci. 2019; 16(4): 519-528. doi:10.7150/ijms.29296
[Abstract] [Full text] [PDF]

Circular RNAs: Novel Promising Biomarkers in Ocular Diseases
Nan Guo, Xiu-fen Liu, Om Prakash Pant, Dan-Dan Zhou, Ji-long Hao, Cheng-wei Lu
Int. J. Med. Sci. 2019; 16(4): 513-518. doi:10.7150/ijms.29750
[Abstract] [Full text] [PDF]

Engineering of Human Corneal Endothelial Cells In Vitro
Qin Zhu, Yingting Zhu, Sean Tighe, Yongsong Liu, Min Hu
Int. J. Med. Sci. 2019; 16(4): 507-512. doi:10.7150/ijms.30759
[Abstract] [Full text] [PDF]

Research Paper
Intrauterine Fetal and Neonatal Death between Small for Date and Non-Small for Date in Small for Gestational Age Infants
Toshiya Itoh, Yoshio Matsuda, Hiroaki Itoh, Masaki Ogawa, Kemal Sasaki, Naohiro Kanayama
Int. J. Med. Sci. 2019; 16(4): 501-506. doi:10.7150/ijms.31153
[Abstract] [Full text] [PDF]

Research Paper
Anti-Cancer Effects of Sulfasalazine and Vitamin E Succinate in MDA-MB 231 Triple-Negative Breast Cancer Cells
Chyou-Wei Wei, Yung-Luen Yu, Ji-Ying Lu, Yu-Ting Hung, Hsiao-Chun Liu, Giou-Teng Yiang
Int. J. Med. Sci. 2019; 16(4): 494-500. doi:10.7150/ijms.30380
[Abstract] [Full text] [PDF]

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