International Journal of Medical Sciences

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22 January 2019

ISSN 1449-1907 News feeds of published articles

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International Journal of Biological Sciences

Journal of Genomics



Journal of Biomedicine

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Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of these polysaccharide-rich extracts in LoVo and HT-29 human colon cancer cells. The in vitro effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Moreover, the effect on anchorage independent-cell growth was also determined. Our results showed that TV and GF extracts did inhibit human colon cell proliferation and induce cytotoxicity.. ...details
A number of biomaterials have been developed, some of which already enjoy widespread clinic use. We have devised a new honeycomb tricalcium phosphate (TCP) containing through-and-through holes of various diameters to control cartilage and bone formation. However, the way in which the geometric structure of the honeycomb TCP controls cartilage and bone tissue formation separately remains unknown. In addition, an association has been reported between bone formation and angiogenesis. Therefore, in the present study, we investigated the relationship between angiogenesis and various hole diameters in our honeycomb TCP over time in a rat ectopic hard tissue formation model.. ...details

Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste and smell, dental sensitivity.

The aim of this observational study was to investigate the prevalence of TMD symptoms and signs as well as oral implications in patients with Early Rheumatoid Arthritis (ERA), that is a RA diagnosed within 12 months, compared with a control group.

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Research Paper
Correlation between genetic polymorphism of angiopoietin-2 gene and clinical aspects of rheumatoid arthritis
Chengqian Dai, Shu-Jui Kuo, Jin Zhao, Lulu Jin, Le Kang, Lihong Wang, Guohong Xu, Chih-Hsin Tang, Chen-Ming Su
Int. J. Med. Sci. 2019; 16(2): 331-336. doi:10.7150/ijms.30582
[Abstract] [Full text] [PDF]

Research Paper
A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia
Jingwen Sun, Jinjing Zhang, Yue Wang, Yan Li, Rui Zhang
Int. J. Med. Sci. 2019; 16(2): 324-330. doi:10.7150/ijms.27757
[Abstract] [Full text] [PDF]

Research Paper
Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock
Elliot Melendez, Jane E. Whitney, Jackson S. Norton, Melanie Silverman, Susanna Harju-Baker, Carmen Mikacenic, Mark M. Wurfel, W. Conrad Liles
Int. J. Med. Sci. 2019; 16(2): 318-323. doi:10.7150/ijms.27731
[Abstract] [Full text] [PDF]

Research Paper
Feasible Advantage of Bioactive/Bioresorbable Devices Made of Forged Composites of Hydroxyapatite Particles and Poly-L-lactide in Alveolar Bone Augmentation: A Preliminary Study
Shintaro Sukegawa, Hotaka Kawai, Keisuke Nakano, Takahiro Kanno, Kiyofumi Takabatake, Hitoshi Nagatsuka, Yoshihiko Furuki
Int. J. Med. Sci. 2019; 16(2): 311-317. doi:10.7150/ijms.27986
[Abstract] [Full text] [PDF]

Research Paper
Imbalance of erythropoiesis and iron metabolism in patients with thalassemia
Yumei Huang, Yu Lei, Rongrong Liu, Jiaodi Liu, Gaohui Yang, Zhifu Xiang, Yuzhen Liang, Yongrong Lai
Int. J. Med. Sci. 2019; 16(2): 302-310. doi:10.7150/ijms.27829
[Abstract] [Full text] [PDF]

Circular RNA: a novel biomarker and therapeutic target for human cancers
Bo Lei, Zhiqiang Tian, Weiping Fan, Bing Ni
Int. J. Med. Sci. 2019; 16(2): 292-301. doi:10.7150/ijms.28047
[Abstract] [Full text] [PDF]

Research Paper
Non-alcoholic fatty liver disease is associated with low-grade albuminuria in men without diabetes mellitus
Seok Hui Kang, Kyu Hyang Cho, Jun Young Do
Int. J. Med. Sci. 2019; 16(2): 285-291. doi:10.7150/ijms.28264
[Abstract] [Full text] [PDF]

Research Paper
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men
Susan M. Graham, Junmei Chen, Jennie Le, Minhua Ling, Dominic W. Chung, W. Conrad Liles, José A. López
Int. J. Med. Sci. 2019; 16(2): 276-284. doi:10.7150/ijms.28110
[Abstract] [Full text] [PDF]

Research Paper
Platelet Reactivity And Circulating Platelet-Derived Microvesicles Are Differently Affected By P2Y12 Receptor Antagonists
Bernadeta Chyrchel, Anna Drożdż, Dorota Długosz, Ewa Ł. Stępień, Andrzej Surdacki
Int. J. Med. Sci. 2019; 16(2): 264-275. doi:10.7150/ijms.28580
[Abstract] [Full text] [PDF]

Research Paper
Temporomandibular Disorders and Oral Features in Early Rheumatoid Arthritis Patients: An Observational Study
Vito Crincoli, Maria Grazia Anelli, Eleonora Quercia, Maria Grazia Piancino, Mariasevera Di Comite
Int. J. Med. Sci. 2019; 16(2): 253-263. doi:10.7150/ijms.28361
[Abstract] [Full text] [PDF]

Research Paper
Reliability of Preoperative Inguinal Sonography for Evaluating Patency of Processus Vaginalis in Pediatric Inguinal Hernia Patients
Jung-Man Namgoong, Won Yong Choi
Int. J. Med. Sci. 2019; 16(2): 247-252. doi:10.7150/ijms.28730
[Abstract] [Full text] [PDF]

Research Paper
MUC7 Level As A New Saliva Risk Factor For Dental Caries In Adult Patients
Anna K. Szkaradkiewicz-Karpińska, Anna Ronij, Olga Goślińska-Kuźniarek, Izabela Przybyłek, Andrzej Szkaradkiewicz
Int. J. Med. Sci. 2019; 16(2): 241-246. doi:10.7150/ijms.29027
[Abstract] [Full text] [PDF]

Research Paper
In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells
Daniel Roca-Lema, Olaia Martinez-Iglesias, Catalina Fernández de Ana Portela, Arturo Rodríguez-Blanco, Manuel Valladares-Ayerbes, Andrea Díaz-Díaz, Alba Casas-Pais, Cecilia Prego, Angélica Figueroa
Int. J. Med. Sci. 2019; 16(2): 231-240. doi:10.7150/ijms.28811
[Abstract] [Full text] [PDF]

Research Paper
A New Look at Causal Factors of Idiopathic Scoliosis: Altered Expression of Genes Controlling Chondroitin Sulfate Sulfation and Corresponding Changes in Protein Synthesis in Vertebral Body Growth Plates
Alla M. Zaydman, Elena L. Strokova, Alena O.Stepanova, Pavel P. Laktionov, Alexander I. Shevchenko, Vladimir M. Subbotin
Int. J. Med. Sci. 2019; 16(2): 221-230. doi:10.7150/ijms.29312
[Abstract] [Full text] [PDF]

Research Paper
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation
Ying-Hsien Huang, Hsing-Chun Kuo, Ya-Ling Yang, Feng-Sheng Wang
Int. J. Med. Sci. 2019; 16(2): 212-220. doi:10.7150/ijms.29930
[Abstract] [Full text] [PDF]

Current status of endovascular treatment for dural arteriovenous fistulae in the anterior cranial fossa: A systematic literature review
Kan Xu, Tiefeng Ji, Chao Li, Jinlu Yu
Int. J. Med. Sci. 2019; 16(2): 203-211. doi:10.7150/ijms.29637
[Abstract] [Full text] [PDF]

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