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International Journal of Biological Sciences
Journal of Cancer
Theranostics
Journal of Genomics
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Official impact factor is 2.244 according to the latest Journal Citation Report from Thomson Reuters.
- Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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Central, Europe PMC, and PMC Canada.
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is ranked very well according to SCImago in the area of
Medicine ...details
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Top cited papers:
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| The number of cancer survivors in the U.S. has increased from 3 million in 1971, when the National Cancer Act was enacted, to over 12 million today. Over 70% of children affected by cancer survive more than 10 years, and most are cured. Most cancer survivors are adults, with two-thirds of them 65 years of age or older and two-thirds alive at five years. The most common cancer diagnoses among survivors include breast, prostate and colorectal cancers. This review was conducted to better appreciate the challenges associated with cancer survivors and the opportunities healthcare providers have in making a difference for these patients.....details |
| In vitro, nitric oxide (NO) has been shown to have antimicrobial activity against a wide range of viruses, including influenza A virus. Therefore, we hypothesized that inhaled nitric oxide (iNO) would increase survival in vivo by reducing the viral load in C57Bl/6 mice infected with a lethal dose of influenza A/WSN/33 (H1N1; WSN/33) virus. NO was delivered to influenza-infected mice either continuously or intermittently at 80 or 160 ppm, respectively, using both prophylactic and post-infection treatment strategies. Murine survival and weight loss were assessed, and lung viral load was quantified via plaque assay. Here, we report that iNO administered prophylactically or post-influenza infection failed to improve survival of infected mice. ....details |
| The number of genetic association studies is increasing exponentially. Nonetheless, genetic association reports are prone to potential biases which may influence the reported outcome.
We hypothesized that positive outcome for a determined polymorphism might be over-reported across genetic association studies analysing a small number of polymorphisms, when compared to studies analysing the same polymorphism together with a high number of other polymorphisms.We systematically reviewed published reports on the association of glutathione s-transferase (GST) single-nucleotide polymorphisms (SNPs) and cancer outcome....details |
| Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per treatment group. Resting metabolic rates (RMR), blood pressure, heart rates and a self-reported rating scale were determined at baseline and 75 min after oral ingestion of the test products in V-8 juice. ...details |
| Adverse event reports (AERs) submitted to the US Food and Drug Administration (FDA) were reviewed to confirm platinum agent-associated adverse events, and to clarify the rank-order of these drugs in terms of susceptibility.
After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving cisplatin (CDDP), carboplatin (CBDCA), or oxaliplatin (L-OHP) were analyzed. Authorized pharmacovigilance tools were used for the quantitative detection of signals, i.e., drug-associated adverse events, including the proportional reporting ratio, the reporting odds ratio, the information component given by a Bayesian confidence propagation neural network, and the empirical Bayes geometric mean. ...details |

Research Paper Genetic Polymorphisms of Matrix Metalloproteinases and Clinical Outcomes in Colorectal Cancer Patients Wen-Chien Ting, Lu-Min Chen, Jiunn-Bey Pao, Ying-Pi Yang, Bang-Jau You, Ta-Yuan Chang, Yu-Hsuan Lan, Hong-Zin Lee, Bo-Ying Bao
Int. J. Med. Sci. 2013; 10(8): 1022-1027. doi:10.7150/ijms.6686
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[PDF] Research Paper Alanine Aminotransferase Elevation during Peginterferon Alpha-2a or Alpha-2b plus Ribavirin Treatment Masato Nakamura, Tatsuo Kanda, Tatsuo Miyamura, Shuang Wu, Shingo Nakamoto, Osamu Yokosuka
Int. J. Med. Sci. 2013; 10(8): 1015-1021. doi:10.7150/ijms.6402
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[PDF] Research Paper Potential Function of Granulysin, Other Related Effector Molecules and Lymphocyte Subsets in Patients with TB and HIV/TB Coinfection Nada Pitabut, Shinsaku Sakurada, Takahiro Tanaka, Chutharut Ridruechai, Junko Tanuma, Takahiro Aoki, Pacharee Kantipong, Surachai Piyaworawong, Nobuyuki Kobayashi, Panadda Dhepakson, Hideki Yanai, Norio Yamada, Shinichi Oka, Masaji Okada, Srisin Khusmith, Naoto Keicho
Int. J. Med. Sci. 2013; 10(8): 1003-1014. doi:10.7150/ijms.6437
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[PDF] Research Paper Overexpression of Integrin-linked Kinase Promotes Lung Cancer Cell Migration and Invasion via NF-κB-mediated Upregulation of Matrix Metalloproteinase-9 Mingjing Zhao, Ying Gao, Lingling Wang, Shuo Liu, Bing Han, Lie Ma, Yuan Ling, Shitao Mao, Xiaoge Wang
Int. J. Med. Sci. 2013; 10(8): 995-1002. doi:10.7150/ijms.5963
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[PDF] Research Paper Lack of Association of C-Met-N375S Sequence Variant with Lung Cancer Susceptibility and Prognosis Jiunn-Min Shieh, Yen-An Tang, Tsung-Han Yang, Chih-Yi Chen, Han-Shui Hsu, Yi-Hung Carol Tan, Ravi Salgia, Yi-Ching Wang
Int. J. Med. Sci. 2013; 10(8): 988-994. doi:10.7150/ijms.5944
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[PDF] Research Paper A Comprehensive Study Indicates PRSS1 Gene Is Significantly Associated with Pancreatitis Jie Liu, Hong-xin Zhang
Int. J. Med. Sci. 2013; 10(8): 981-987. doi:10.7150/ijms.6164
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[PDF] Research Paper Combination with Anthropometric Measurements and MQSGA to Assess Nutritional Status in Chinese Hemodialysis Population Jie Chen, Hongquan Peng, Zhimin Yuan, Kun Zhang, Long Xiao, Jialian Huang, Jingfeng Wang, Hui Huang
Int. J. Med. Sci. 2013; 10(8): 974-980. doi:10.7150/ijms.5811
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[PDF] Research Paper Pneumothorax as an Adverse Drug Event: An Exploratory Aggregate Analysis of the US FDA AERS Database Including A Confounding By Indication Analysis Inspired by Cornfield's Condition Manfred Hauben, Eric Y. Hung
Int. J. Med. Sci. 2013; 10(8): 965-973. doi:10.7150/ijms.5377
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[PDF] Research Paper Inhibition of HCV 5′-NTR and Core Expression by a Small Hairpin RNA Delivered by a Histone Gene Carrier, HPhA Yanhua Ding, Hong Zhang, Yuxiang Li, Di Wu, Shumei He, Yang Wang, Yuanyuan Li, Feng Wang, Junqi Niu
Int. J. Med. Sci. 2013; 10(8): 957-964. doi:10.7150/ijms.5632
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[PDF] Research Paper Down-Regulated CK8 Expression in Human Intervertebral Disc Degeneration Zhen Sun, Hai-Qiang Wang, Zhi-Heng Liu, Le Chang, Yu-Fei Chen, Yong-Zhao Zhang, Wei-Lin Zhang, Yang Gao, Zhong-Yuan Wan, Lu Che, Xu Liu, Dino Samartzis, Zhuo-Jing Luo
Int. J. Med. Sci. 2013; 10(8): 948-956. doi:10.7150/ijms.5642
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[PDF] Research Paper C-Reactive Protein and Serum Amyloid A Overexpression in Lung Tissues of Chronic Obstructive Pulmonary Disease Patients: A Case-Control Study Jose Luis López-Campos, Carmen Calero, Belén Rojano, Marta López-Porras, Javier Sáenz-Coronilla, Ana I Blanco, Verónica Sánchez-López, Daniela Tobar, Ana Montes-Worboys, Elena Arellano
Int. J. Med. Sci. 2013; 10(8): 938-947. doi:10.7150/ijms.6152
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[PDF] Research Paper Influence of CYP2D6 Polymorphisms on Serum Levels of Tamoxifen Metabolites in Spanish Women with Breast Cancer Mercedes Zafra-Ceres, Tomas de Haro, Esther Farez-Vidal, Isabel Blancas, Fernando Bandres, Eduardo Martinez de Dueñas, Enrique Ochoa-Aranda, Jose A. Gomez-Capilla, Carolina Gomez-Llorente
Int. J. Med. Sci. 2013; 10(7): 932-937. doi:10.7150/ijms.5708
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[PDF] Research Paper Lyme Borreliosis in Human Patients in Florida and Georgia, USA Kerry L. Clark, Brian Leydet, Shirley Hartman
Int. J. Med. Sci. 2013; 10(7): 915-931. doi:10.7150/ijms.6273
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[PDF] Research Paper Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice Yi-Zhan Xing, Rui-Min Wang, Ke Yang, Hai-Ying Guo, Fang Deng, Yu-Hong Li, Ji-Xing Ye, Long He, Xiao-Hua Lian, Tian Yang
Int. J. Med. Sci. 2013; 10(7): 908-914. doi:10.7150/ijms.6137
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[PDF] Research Paper Procalcitonin-Guided Antibiotic Use in Acute Exacerbations of Idiopathic Pulmonary Fibrosis Juanjuan Ding, Zhuochang Chen, Keqing Feng
Int. J. Med. Sci. 2013; 10(7): 903-907. doi:10.7150/ijms.4972
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[PDF] Research Paper Evaluation of Clinical Value of Single Nucleotide Polymorphisms of Dihydropyrimidine Dehydrogenase Gene to Predict 5-Fluorouracil Toxicity in 60 Colorectal Cancer Patients in China Xin Zhang, Butong Sun, Zhenxia Lu
Int. J. Med. Sci. 2013; 10(7): 894-902. doi:10.7150/ijms.5556
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