International Journal of Medical Sciences
Official Impact Factor

21 October 2016

ISSN 1449-1907 News feeds of published articles

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new Impact factor is 2.232 according to 2016 release of Journal Citation Reports®. Congratulations!

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Amplification and overexpression of CTTN and CCND1 at chromosome 11q13 in Esophagus squamous cell carcinoma (ESCC) of North Eastern Chinese Population
Xiaoxia Hu, Ji Wook Moon, Shibo Li, Weihong Xu, Xianfu Wang, Yuanyuan Liu, Ji-Yun Lee
Int. J. Med. Sci. 2016; 13(11): 868-874. doi:10.7150/ijms.16845
[Abstract] [Full text] [PDF]

Research Paper
Activation of the CXCL16/CXCR6 Pathway by Inflammation Contributes to Atherosclerosis in Patients with End-stage Renal Disease
Ze Bo Hu, Yan Chen, Yu Xiang Gong, Min Gao, Yang Zhang, Gui Hua Wang, Ri Ning Tang, Hong Liu, Bi Cheng Liu, Kun Ling Ma
Int. J. Med. Sci. 2016; 13(11): 858-867. doi:10.7150/ijms.16724
[Abstract] [Full text] [PDF]

Research Paper
Amelioration of estrogen deficiency-induced obesity by collagen hydrolysate
Tsay-I Chiang, I-Chang Chang, Hsueh-Hui Lee, Kuang hui Hsieh, Yung-Wei Chiu, Te-Jen Lai, Jer-Yuh Liu, Li-Sung Hsu, Shao-Hsuan Kao
Int. J. Med. Sci. 2016; 13(11): 853-857. doi:10.7150/ijms.16706
[Abstract] [Full text] [PDF]

Research Paper
Cardiomyogenic Differentiation of Human Dental Follicle-derived Stem Cells by Suberoylanilide Hydroxamic Acid and Their In Vivo Homing Property
Iel-Yong Sung, Han-Na Son, Imran Ullah, Dinesh Bharti, Ju-Mi Park, Yeong-Cheol Cho, June-Ho Byun, Young-Hoon Kang, Su-Jin Sung, Jong-Woo Kim, Gyu-Jin Rho, Bong-Wook Park
Int. J. Med. Sci. 2016; 13(11): 841-852. doi:10.7150/ijms.16573
[Abstract] [Full text] [PDF]

The Limbal Epithelial Progenitors in the Limbal Niche Environment
Yuan Zhang, Hong Sun, Yongsong Liu, Shuangling Chen, Subo Cai, Yingting Zhu, Ping Guo
Int. J. Med. Sci. 2016; 13(11): 835-840. doi:10.7150/ijms.16563
[Abstract] [Full text] [PDF]

Research Paper
Association between Benzodiazepine Use and Dementia: Data Mining of Different Medical Databases
Mitsutaka Takada, Mai Fujimoto, Kouichi Hosomi
Int. J. Med. Sci. 2016; 13(11): 825-834. doi:10.7150/ijms.16185
[Abstract] [Full text] [PDF]

Research Paper
Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters
Pei-Yu Chao, James A. Lin, Wei-Jen Ting, Hsueh-Hui Lee, Kuanghui Hsieh, Yung-Wei Chiu, Te-Jen Lai, Jin-Ming Hwang, Je-rYuh Liu, Chih-Yang Huang
Int. J. Med. Sci. 2016; 13(11): 819-824. doi:10.7150/ijms.16474
[Abstract] [Full text] [PDF]

Research Paper
Cultured Human Periosteum-Derived Cells Can Differentiate into Osteoblasts in a Perioxisome Proliferator-Activated Receptor Gamma-Mediated Fashion via Bone Morphogenetic Protein signaling
Jin-Eun Chung, Jin-Ho Park, Jeong-Won Yun, Young-Hoon Kang, Bong-Wook Park, Sun-Chul Hwang, Yeong-Cheol Cho, Iel-Yong Sung, Dong Kyun Woo, June-Ho Byun
Int. J. Med. Sci. 2016; 13(11): 806-818. doi:10.7150/ijms.16484
[Abstract] [Full text] [PDF]

Research Paper
Lacrimal Duct Occlusion Is Associated with Infectious Keratitis
Guigang Li, Jingmin Guo, Rong Liu, Weikun Hu, Lingjuan Xu, Juan Wang, Subo Cai, Hong Zhang, Yingting Zhu
Int. J. Med. Sci. 2016; 13(10): 800-805. doi:10.7150/ijms.16515
[Abstract] [Full text] [PDF]

Clinical importance of the middle meningeal artery: A review of the literature
Jinlu Yu, Yunbao Guo, Baofeng Xu, Kan Xu
Int. J. Med. Sci. 2016; 13(10): 790-799. doi:10.7150/ijms.16489
[Abstract] [Full text] [PDF]

Research Paper
Targeting P38 Pathway Regulates Bony Formation via MSC Recruitment during Mandibular Distraction Osteogenesis in Rats
Zi-hui Yang, Bao-lei Wu, Chen Ye, Sen Jia, Xin-jie Yang, Rui Hou, De-lin Lei, Lei Wang
Int. J. Med. Sci. 2016; 13(10): 783-789. doi:10.7150/ijms.16663
[Abstract] [Full text] [PDF]

Research Paper
Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice
Karolina Niska, Narcyz Knap, Anna Kędzia, Maciej Jaskiewicz, Wojciech Kamysz, Iwona Inkielewicz-Stepniak
Int. J. Med. Sci. 2016; 13(10): 772-782. doi:10.7150/ijms.16011
[Abstract] [Full text] [PDF]

Research Paper
Immunohistochemical study of hair follicle stem cells in regenerated hair follicles induced by Wnt10b
Yiming Zhang, Yizhan Xing, Haiying Guo, Xiaogen Ma, Yuhong Li
Int. J. Med. Sci. 2016; 13(10): 765-771. doi:10.7150/ijms.16118
[Abstract] [Full text] [PDF]

Research Paper
Tissue factor: A potent stimulator of Von Willebrand factor synthesis by human umbilical vein endothelial cells
Muriel Meiring, W. Allers, E. Le Roux
Int. J. Med. Sci. 2016; 13(10): 759-764. doi:10.7150/ijms.15688
[Abstract] [Full text] [PDF]

Research Paper
Role of CAPE on cardiomyocyte protection via connexin 43 regulation under hypoxia
Chien-Cheng Chen, Chan-Yen Kuo, Rong-Fu Chen
Int. J. Med. Sci. 2016; 13(10): 754-758. doi:10.7150/ijms.15847
[Abstract] [Full text] [PDF]

Research Paper
Lower Body Mass Index is a Risk Factor for In-Hospital Mortality of Elderly Japanese Patients Treated with Ampicillin/sulbactam
Makoto Miura, Akiko Kuwahara, Akinori Tomozawa, Naoki Omae, Motohiro Yamamori, Kaori Kadoyama, Toshiyuki Sakaeda
Int. J. Med. Sci. 2016; 13(10): 749-753. doi:10.7150/ijms.16090
[Abstract] [Full text] [PDF]

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