International Journal of Medical Sciences
Official Impact Factor

24 May 2016

ISSN 1449-1907 News feeds of published articles

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Call for papers - Journal of Bone and Joint Infection - official publication of European Bone and Joint Infection Society

International Journal of Biological Sciences

Journal of Cancer

Theranostics

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Detection of Human Papillomavirus 16-Specific IgG and IgM Antibodies in Patient Sera: A Potential Indicator of Oral Squamous Cell Carcinoma Risk Factor
Jesinda P. Kerishnan, Subash C.B. Gopinath, Sia Bik Kai, Thean-Hock Tang, Helen Lee-Ching Ng, Zainal Ariff Abdul Rahman, Uda Hashim, Yeng Chen
Int. J. Med. Sci. 2016; 13(6): 424-431. doi:10.7150/ijms.14475
[Abstract] [Full text] [PDF]

Research Paper
Daclatasvir plus Asunaprevir Treatment for Real-World HCV Genotype 1-Infected Patients in Japan
Tatsuo Kanda, Shin Yasui, Masato Nakamura, Eiichiro Suzuki, Makoto Arai, Yuki Haga, Reina Sasaki, Shuang Wu, Shingo Nakamoto, Fumio Imazeki, Osamu Yokosuka
Int. J. Med. Sci. 2016; 13(6): 418-423. doi:10.7150/ijms.15519
[Abstract] [Full text] [PDF]

Research Paper
The Expression of Gli3 and Teashirt3 in the Stenotic Tissue of Congenital Pelvi-Ureteric Junction Obstruction in Children
Hui Chen, Hong-Ying Ji, Yi Yang
Int. J. Med. Sci. 2016; 13(6): 412-417. doi:10.7150/ijms.14880
[Abstract] [Full text] [PDF]

Research Paper
ECG-Guided Surveillance Technique in Cryoballoon Ablation for Paroxysmal and Persistent Atrial Fibrillation: A Strategy to Prevent From Phrenic Nerve Palsy
Axel Meissner, Petra Maagh, Arndt Christoph, Ahmet Oernek, Gunnar Plehn
Int. J. Med. Sci. 2016; 13(6): 403-411. doi:10.7150/ijms.14383
[Abstract] [Full text] [PDF]

Research Paper
Glycated Albumin Predicts Long-term Survival in Patients Undergoing Hemodialysis
Chien-Lin Lu, Wen-Ya Ma, Yuh-Feng Lin, Jia-Fwu Shyu, Yuan-Hung Wang, Yueh-Min Liu, Chia-Chao Wu, Kuo-Cheng Lu
Int. J. Med. Sci. 2016; 13(5): 395-402. doi:10.7150/ijms.14259
[Abstract] [Full text] [PDF]

Research Paper
OCT4 Remodels the Phenotype and Promotes Angiogenesis of HUVECs by Changing the Gene Expression Profile
Yan Mou, Zhen Yue, Xiaotong Wang, Wenxue Li, Haiying Zhang, Yang Wang, Ronggui Li, Xin Sun
Int. J. Med. Sci. 2016; 13(5): 386-394. doi:10.7150/ijms.15057
[Abstract] [Full text] [PDF]

Review
An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer
Sanaz Koosha, Mohammed A. Alshawsh, Chung Yeng Looi, Atefehalsadat Seyedan, Zahurin Mohamed
Int. J. Med. Sci. 2016; 13(5): 374-385. doi:10.7150/ijms.14485
[Abstract] [Full text] [PDF]

Research Paper
EphB4/ephrinB2 Contributes to Imatinib Resistance in Chronic Myeloid Leukemia Involved in Cytoskeletal Proteins
Lin Li, Na Xu, Jin-fang Zhang, Lu-lu Xu, Xuan Zhou, Bin-tao Huang, Yu-ling Li, Xiao-li Liu
Int. J. Med. Sci. 2016; 13(5): 365-373. doi:10.7150/ijms.14989
[Abstract] [Full text] [PDF]

Research Paper
Autophagy Has a Beneficial Role in Relieving Cigarette Smoke-Induced Apoptotic Death in Human Gingival Fibroblasts
Moon-Soo Kim, Jeong-Won Yun, Jin-Ho Park, Bong-Wook Park, Young-Hoon Kang, Young-Sool Hah, Sun-Chul Hwang, Dong Kyun Woo, June-Ho Byun
Int. J. Med. Sci. 2016; 13(5): 357-364. doi:10.7150/ijms.14592
[Abstract] [Full text] [PDF]

Research Paper
The Influence of Acute Hyperglycemia in an Animal Model of Lacunar Stroke That Is Induced by Artificial Particle Embolization
Ming-Jun Tsai, Ming-Wei Lin, Yaw-Bin Huang, Yu-Min Kuo, Yi-Hung Tsai
Int. J. Med. Sci. 2016; 13(5): 347-356. doi:10.7150/ijms.14393
[Abstract] [Full text] [PDF]

Research Paper
Screening for Fabry Disease by Urinary Globotriaosylceramide Isoforms Measurement in Patients with Left Ventricular Hypertrophy
Martina Gaggl, Natalija Lajic, Georg Heinze, Till Voigtländer, Raute Sunder-Plassmann, Eduard Paschke, Günter Fauler, Gere Sunder-Plassmann, Gerald Mundigler
Int. J. Med. Sci. 2016; 13(5): 340-346. doi:10.7150/ijms.14997
[Abstract] [Full text] [PDF]

Research Paper
Secretion of N- and O-linked Glycoproteins from 4T1 Murine Mammary Carcinoma Cells
Wai-Mei Phang, Aik-Aun Tan, Subash C.B. Gopinath, Onn H. Hashim, Lik Voon Kiew, Yeng Chen
Int. J. Med. Sci. 2016; 13(5): 330-339. doi:10.7150/ijms.14341
[Abstract] [Full text] [PDF]

Research Paper
Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study
Tarja Kunnas, Kirsi Määttä, Seppo T Nikkari
Int. J. Med. Sci. 2016; 13(5): 325-329. doi:10.7150/ijms.14849
[Abstract] [Full text] [PDF]

Research Paper
Prevalence of the Lyme Disease Spirochete, Borrelia burgdorferi, in Blacklegged Ticks, Ixodes scapularis at Hamilton-Wentworth, Ontario
John D. Scott, John F. Anderson, Lance A. Durden, Morgan L. Smith, Jodi M. Manord, Kerry L. Clark
Int. J. Med. Sci. 2016; 13(5): 316-324. doi:10.7150/ijms.14552
[Abstract] [Full text] [PDF]

Research Paper
Sustained Virologic Response at 24 Weeks after the End of Treatment Is a Better Predictor for Treatment Outcome in Real-World HCV-Infected Patients Treated by HCV NS3/4A Protease Inhibitors with Peginterferon plus Ribavirin
Tatsuo Kanda, Shingo Nakamoto, Reina Sasaki, Masato Nakamura, Shin Yasui, Yuki Haga, Sadahisa Ogasawara, Akinobu Tawada, Makoto Arai, Shigeru Mikami, Fumio Imazeki, Osamu Yokosuka
Int. J. Med. Sci. 2016; 13(4): 310-315. doi:10.7150/ijms.14953
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Effects of HMGB1 Polymorphisms on the Susceptibility and Progression of Hepatocellular Carcinoma
Bin Wang, Chao-Bin Yeh, Ming-Yu Lein, Chen-Ming Su, Shun-Fa Yang, Yu-Fan Liu, Chih-Hsin Tang
Int. J. Med. Sci. 2016; 13(4): 304-309. doi:10.7150/ijms.14877
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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