International Journal of Medical Sciences

Impact factor
2.399

19 September 2017

ISSN 1449-1907 News feeds of published articles

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new Impact factor is 2.399 according to 2017 release of Journal Citation Reports®. Congratulations!

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
MEF2C loss-of-function mutation contributes to congenital heart defects
Xiao-Hui Qiao, Fei Wang, Xian-Ling Zhang, Ri-Tai Huang, Song Xue, Juan Wang, Xing-Biao Qiu, Xing-Yuan Liu, Yi-Qing Yang
Int. J. Med. Sci. 2017; 14(11): 1143-1153. doi:10.7150/ijms.21353
[Abstract] [Full text] [PDF]

Research Paper
Extensively disturbance of regulatory T cells - Th17 cells balance in stage II pulmonary sarcoidosis
Jingjing Ding, Jinghong Dai, Hourong Cai, Qian Gao, Yanting Wen
Int. J. Med. Sci. 2017; 14(11): 1136-1142. doi:10.7150/ijms.18838
[Abstract] [Full text] [PDF]

Research Paper
Genetic Variations of Melatonin Receptor Type 1A are Associated with the Clinicopathologic Development of Urothelial Cell Carcinoma
Yung-Wei Lin, Shian-Shiang Wang, Yu-Ching Wen, Min-Che Tung, Liang-Ming Lee, Shun-Fa Yang, Ming-Hsien Chien
Int. J. Med. Sci. 2017; 14(11): 1130-1135. doi:10.7150/ijms.20629
[Abstract] [Full text] [PDF]

Research Paper
The Crosstalk between HDPSCs and HUCMSCs on Proliferation and Osteogenic Genes Expression in Coculture System
Linglu Jia, Weiting Gu, Yunpeng Zhang, Yawen Ji, Jin Liang, Yong Wen, Xin Xu
Int. J. Med. Sci. 2017; 14(11): 1118-1129. doi:10.7150/ijms.19814
[Abstract] [Full text] [PDF]

Research Paper
Effect of Coriolus versicolor Mycelia Extract on Exercise Performance and Physical Fatigue in Mice
Chun-Sheng Ho, Yu-Tang Tung, Woon-Man Kung, Wen-Ching Huang, Wing-Ki Leung, Chi-Chang Huang, Jyh-Horng Wu
Int. J. Med. Sci. 2017; 14(11): 1110-1117. doi:10.7150/ijms.20547
[Abstract] [Full text] [PDF]

Research Paper
Selective Killing of Melanoma Cells With Non-Thermal Atmospheric Pressure Plasma and p-FAK Antibody Conjugated Gold Nanoparticles
Byul Bo Ra Choi, Jeong Hae Choi, Jin Woo Hong, Ki Won Song, Hae June Lee, Uk Kyu Kim, Gyoo Cheon Kim
Int. J. Med. Sci. 2017; 14(11): 1101-1109. doi:10.7150/ijms.20104
[Abstract] [Full text] [PDF]

Research Paper
Plasma Levels of Endothelial Cell-Specific Molecule-1 as a Potential Biomarker of Oral Cancer Progression
Wei-En Yang, Ming-Ju Hsieh, Chiao-Wen Lin, Chun-Ying Kuo, Shun-Fa Yang, Chun-Yi Chuang, Mu-Kuan Chen
Int. J. Med. Sci. 2017; 14(11): 1094-1100. doi:10.7150/ijms.20414
[Abstract] [Full text] [PDF]

Research Paper
Association of IFNL3 Genotype with Hepatic Steatosis in Chronic Hepatitis C Patients Treated with Peginterferon and Ribavirin Combination Therapy
Shingo Nakamoto, Fumio Imazeki, Tatsuo Kanda, Shuang Wu, Masato Nakamura, Shin Yasui, Akinobu Tawada, Rintaro Mikata, Tetsuhiro Chiba, Makoto Arai, Osamu Yokosuka, Hiroshi Shirasawa
Int. J. Med. Sci. 2017; 14(11): 1088-1093. doi:10.7150/ijms.20171
[Abstract] [Full text] [PDF]

Research Paper
Serum 1,25-dihydroxyvitamin D Better Reflects Renal Parameters Than 25-hydoxyvitamin D in Patients with Glomerular Diseases
Sungjin Chung, Minyoung Kim, Eun Sil Koh, Hyeon Seok Hwang, Yoon Kyung Chang, Cheol Whee Park, Suk Young Kim, Yoon Sik Chang, Yu Ah Hong
Int. J. Med. Sci. 2017; 14(11): 1080-1087. doi:10.7150/ijms.20452
[Abstract] [Full text] [PDF]

Research Paper
Construction and Identification of Recombinant HEK293T Cell Lines Expressing Non-structural Protein 1 of Zika Virus
Jun Liu, Pengfei Wan, Qingqing Li, Xiaoxin Li, Andrew Li, Huangyao Chen, Jingjing Li, Wenhan Liang, Haifa Zheng, Weiwang Gu, Hongwei Li
Int. J. Med. Sci. 2017; 14(11): 1072-1079. doi:10.7150/ijms.20417
[Abstract] [Full text] [PDF]

Research Paper
Effects Of Oral Glutamine on Inflammatory and Autophagy Responses in Cancer Patients Treated With Abdominal Radiotherapy: A Pilot Randomized Trial
Juan J. Ortiz de Urbina, Beatriz San-Miguel, Alfonso Vidal-Casariego, Irene Crespo, Diana I. Sánchez, José L. Mauriz, Jesús M. Culebras, Javier González-Gallego, María J. Tuñón
Int. J. Med. Sci. 2017; 14(11): 1065-1071. doi:10.7150/ijms.20245
[Abstract] [Full text] [PDF]

Research Paper
Gender-Specific Associations between Low Skeletal Muscle Mass and Albuminuria in the Middle-Aged and Elderly Population
Hye Eun Yoon, Yunju Nam, Eunjin Kang, Hyeon Seok Hwang, Seok Joon Shin, Yeon Sik Hong, Kwi Young Kang
Int. J. Med. Sci. 2017; 14(11): 1054-1064. doi:10.7150/ijms.20286
[Abstract] [Full text] [PDF]

Research Paper
The Extracts of Astragalus membranaceus Inhibit Melanogenesis through the ERK Signaling Pathway
Yu-Tzu Tsao, Chun-Yu Kuo, Yu-Diao Kuan, Han-Chen Lin, Li-Hsien Wu, Che-Hsin Lee
Int. J. Med. Sci. 2017; 14(11): 1049-1053. doi:10.7150/ijms.20335
[Abstract] [Full text] [PDF]

Research Paper
Sports and HDL-Quality Reflected By Serum Amyloid A and Surfactant Protein B
Michael Sponder, Chantal Kopecky, Ioana-Alexandra Campean, Michael Emich, Monika Fritzer-Szekeres, Brigitte Litschauer, Senta Graf, Marcus D. Säemann, Jeanette Strametz-Juranek
Int. J. Med. Sci. 2017; 14(11): 1040-1048. doi:10.7150/ijms.20388
[Abstract] [Full text] [PDF]

Research Paper
Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation
Min Chen, Liang Zhong, Shi-Fei Yao, Yi Zhao, Lu Liu, Lian-Wen Li, Ting Xu, Liu-Gen Gan, Chun-Lan Xiao, Zhi-Ling Shan, Bei-Zhong Liu
Int. J. Med. Sci. 2017; 14(10): 1031-1039. doi:10.7150/ijms.19682
[Abstract] [Full text] [PDF]

Research Paper
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR
Guanglin Chen, Lei Peng, Zhongxian Zhu, Chunxia Du, Ziyang Shen, Rujin Zang, Yang Su, Yankai Xia, Weibing Tang
Int. J. Med. Sci. 2017; 14(10): 1022-1030. doi:10.7150/ijms.18392
[Abstract] [Full text] [PDF]

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