International Journal of Medical Sciences

Impact factor
2.399

19 June 2018

ISSN 1449-1907 News feeds of published articles

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Theranostics

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International Journal of Biological Sciences

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Journal of Bone and Joint Infection (JBJI)

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Impact factor is 2.399 according to 2017 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects
Wen-Chang Wang, Yen-Feng Chiu, Ren-Hua Chung, Chii-Min Hwu, I-Te Lee, Chien-Hsing Lee, Yi-Cheng Chang, Kuan-Yi Hung, Thomas Quertermous, Yii-Der I. Chen, Chao A. Hsiung
Int. J. Med. Sci. 2018; 15(11): 1035-1042. doi:10.7150/ijms.25742
[Abstract] [Full text] [PDF]

Research Paper
The Combination Of Weak Expression Of PRDX4 And Very High MIB-1 Labelling Index Independently Predicts Shorter Disease-free Survival In Stage I Lung Adenocarcinoma
Akihiro Shioya, Xin Guo, Nozomu Motono, Seiya Mizuguchi, Nozomu Kurose, Satoko Nakada, Akane Aikawa, Yoshitaka Ikeda, Hidetaka Uramoto, Sohsuke Yamada
Int. J. Med. Sci. 2018; 15(10): 1025-1034. doi:10.7150/ijms.25734
[Abstract] [Full text] [PDF]

Research Paper
Trehalose inhibits H2O2-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activation
Zhijie Gao, Helei Wang, Bo Zhang, Xuemei Wu, Yanfeng Zhang, Pengfei Ge, Guangfan Chi, Jianmin Liang
Int. J. Med. Sci. 2018; 15(10): 1014-1024. doi:10.7150/ijms.25656
[Abstract] [Full text] [PDF]

Research Paper
Relationship of genetic variant distributions of WW domain-containing oxidoreductase gene with uterine cervical cancer
Yu-Hsiang Lin, Yi-Hsuan Hsiao, Wen-Jun Wu, Shun-Fa Yang, Chun-Fang Hsu, Yu-Ting Kang, Po-Hui Wang
Int. J. Med. Sci. 2018; 15(10): 1005-1013. doi:10.7150/ijms.25553
[Abstract] [Full text] [PDF]

Research Paper
AKAP11 gene polymorphism is associated with bone mass measured by quantitative ultrasound in young adults
María Correa-Rodríguez, Jacqueline Schmidt Rio-Valle, Blanca Rueda-Medina
Int. J. Med. Sci. 2018; 15(10): 999-1004. doi:10.7150/ijms.25369
[Abstract] [Full text] [PDF]

Research Paper
CDKN3 expression is an independent prognostic factor and associated with advanced tumor stage in nasopharyngeal carcinoma
Shih-Lun Chang, Tzu-Ju Chen, Ying-En Lee, Sung-Wei Lee, Li-Ching Lin, Hong-Lin He
Int. J. Med. Sci. 2018; 15(10): 992-998. doi:10.7150/ijms.25065
[Abstract] [Full text] [PDF]

Short Research Communication
Regulation of TLR4 in silica-induced inflammation: An underlying mechanism of silicosis
Judy Yuet Wa Chan, Joseph Chi Ching Tsui, Patrick Tik Wan Law, Winnie Kwok Wei So, Doris Yin Ping Leung, Michael Mau Kwong Sham, Stephen Kwok Wing Tsui, Carmen Wing Han Chan
Int. J. Med. Sci. 2018; 15(10): 986-991. doi:10.7150/ijms.24715
[Abstract] [Full text] [PDF]

Research Paper
Endothelial-cell inflammation and damage by reactive oxygen species are prevented by propofol via ABCA1-mediated cholesterol efflux
Chih-Peng Hsu, Chih-Hung Lin, Chan-Yen Kuo
Int. J. Med. Sci. 2018; 15(10): 978-985. doi:10.7150/ijms.24659
[Abstract] [Full text] [PDF]

Research Paper
RANKL Reduces Body Weight and Food Intake via the Modulation of Hypothalamic NPY/CART Expression
Ping Zhu, Zhihui Zhang, Xufeng Huang, Shiyu Liang, Neeta Khandekar, Zhiyuan Song, Shu Lin
Int. J. Med. Sci. 2018; 15(10): 969-977. doi:10.7150/ijms.24373
[Abstract] [Full text] [PDF]

Research Paper
Efficacy of Palonosetron-Dexamethasone Combination Versus Palonosetron Alone for Preventing Nausea and Vomiting Related to Opioid-Based Analgesia: A Prospective, Randomized, Double-blind Trial
Eunah Cho, Do-Hyeong Kim, Seokyung Shin, Seung Hyun Kim, Young Jun Oh, Yong Seon Choi
Int. J. Med. Sci. 2018; 15(10): 961-968. doi:10.7150/ijms.24230
[Abstract] [Full text] [PDF]

Research Paper
Manual acupuncture relieves bile acid-induced itch in mice: the role of microglia and TNF-α
Yu-Chen Lee, Chia-Hsien Lin, Shih-Ya Hung, Hsin-Yi Chung, Sih-Ting Luo, Iona MacDonald, Yu-Ting Chu, Pei-Lin Lin, Yi-Hung Chen
Int. J. Med. Sci. 2018; 15(9): 953-960. doi:10.7150/ijms.24146
[Abstract] [Full text] [PDF]

Research Paper
Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells
Adriana Di Benedetto, Francesca Posa, Salvatore De Maria, Giampietro Ravagnan, Andrea Ballini, Chiara Porro, Teresa Trotta, Maria Grano, Lorenzo Lo Muzio, Giorgio Mori
Int. J. Med. Sci. 2018; 15(9): 944-952. doi:10.7150/ijms.24111
[Abstract] [Full text] [PDF]

Research Paper
Susceptibility to serious skin and subcutaneous tissue disorders and skin tissue distribution of sodium-dependent glucose co-transporter type 2 (SGLT2) inhibitors
Toshiyuki Sakaeda, Shinji Kobuchi, Ryosuke Yoshioka, Mariko Haruna, Noriko Takahata, Yukako Ito, Aki Sugano, Kazuki Fukuzawa, Toshiki Hayase, Taro Hayakawa, Hideo Nakayama, Yutaka Takaoka, Masahiro Tohkin
Int. J. Med. Sci. 2018; 15(9): 937-943. doi:10.7150/ijms.22224
[Abstract] [Full text] [PDF]

Research Paper
Anti-inflammation and Anti-Cancer Activity of Ethanol Extract of Antarctic Freshwater Microalga, Micractinium sp.
Sung-Suk Suh, Ju-Mi Hong, Eun Jae Kim, Seung Won Jung, Sun-Mi Kim, Jung Eun Kim, Il-Chan Kim, Sanghee Kim
Int. J. Med. Sci. 2018; 15(9): 929-936. doi:10.7150/ijms.26410
[Abstract] [Full text] [PDF]

Research Paper
Recovery effect of pre-germinated brown rice on the changes of sperm quality, testicular structure and androgen receptor expression in a rat model of drug addiction
Samur Thanoi, Jureepon Roboon, Sutisa Nudmamud-Thanoi
Int. J. Med. Sci. 2018; 15(9): 921-928. doi:10.7150/ijms.26076
[Abstract] [Full text] [PDF]

Research Paper
Co-infection Of Ureaplasma urealyticum And Human Papilloma Virus In Asymptomatic Sexually Active Individuals
Sang Il Kim, Joo Hee Yoon, Dong Choon Park, Dong Sup Lee, Seung Ju Lee, Hyun Sop Choe, Jin Hwi Kim, Tae Chul Park, Sung Jong Lee
Int. J. Med. Sci. 2018; 15(9): 915-920. doi:10.7150/ijms.26523
[Abstract] [Full text] [PDF]

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