International Journal of Medical Sciences

Impact factor

25 May 2018

ISSN 1449-1907 News feeds of published articles

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Journal of Bone and Joint Infection (JBJI)


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  • This Journal is ranked very well according to SCImago in the area of Medicine ...details

Impact factor is 2.399 according to 2017 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
The suppression of DUSP5 expression correlates with paclitaxel resistance and poor prognosis in basal-like breast cancer
Tieju Liu, Huizhi Sun, Shiqi Liu, Zhao Yang, Linqi Li, Nan Yao, Siqi Cheng, Xueyi Dong, Xiaohui Liang, Chen Chen, Yi Wang, Xiulan Zhao
Int. J. Med. Sci. 2018; 15(7): 738-747. doi:10.7150/ijms.24981
[Abstract] [Full text] [PDF]

Research Paper
Prognostic Utility of Soluble Suppression of Tumorigenicity 2 level as a Predictor of Clinical Outcomes in Incident Hemodialysis Patients
Suk Min Seo, Sun Hwa Kim, Yaeni Kim, Hye Eun Yoon, Seok Joon Shin
Int. J. Med. Sci. 2018; 15(7): 730-737. doi:10.7150/ijms.23638
[Abstract] [Full text] [PDF]

Research Paper
Propofol attenuates osteoclastogenesis by lowering RANKL/OPG ratio in mouse osteoblasts
Do-Won Lee, Jae-Young Kwon, Hae-Kyu Kim, Hyeon-Jeong Lee, Eun-Soo Kim, Hyae-Jin Kim, Hyung-Joon Kim, Han-Bit Lee
Int. J. Med. Sci. 2018; 15(7): 723-729. doi:10.7150/ijms.22713
[Abstract] [Full text] [PDF]

Lipid Emulsion for Treating Local Anesthetic Systemic Toxicity
Seong-Ho Ok, Jeong-Min Hong, Soo Hee Lee, Ju-Tae Sohn
Int. J. Med. Sci. 2018; 15(7): 713-722. doi:10.7150/ijms.22643
[Abstract] [Full text] [PDF]

Research Paper
Differential Expression of CircRNAs in Embryonic Heart Tissue Associated with Ventricular Septal Defect
Heng Liu, Yin Hu, Bin Zhuang, Jing Yin, Xiao-Hui Chen, Juan Wang, Meng-Meng Li, Jing Xu, Xing-Yun Wang, Zhang-Bin Yu, Shu-Ping Han
Int. J. Med. Sci. 2018; 15(7): 703-712. doi:10.7150/ijms.21660
[Abstract] [Full text] [PDF]

Research Paper
Low-Dose Evans Blue Dye for Near-Infrared Fluorescence Imaging in Photothrombotic Stroke Model
Hye-Won Ryu, Wonbong Lim, Danbi Jo, Subin Kim, Jong Tae Park, Jung-Joon Min, Hoon Hyun, Hyung-Seok Kim
Int. J. Med. Sci. 2018; 15(7): 696-702. doi:10.7150/ijms.24257
[Abstract] [Full text] [PDF]

Research Paper
Development of an Anti-Adhesive Membrane for Use in Video-Assisted Thoracic Surgery
Akiko Uemura, Toshiharu Fukayama, Takashi Tanaka, Yasuko Hasegawa-Baba, Makoto Shibutani, Ryou Tanaka
Int. J. Med. Sci. 2018; 15(7): 689-695. doi:10.7150/ijms.24050
[Abstract] [Full text] [PDF]

Research Paper
Chronic Alcohol Consumption Inhibits Autophagy and Promotes Apoptosis in the Liver
Mario Menk, Jan Adriaan Graw, Deniz Poyraz, Nadine Möbius, Claudia D. Spies, Clarissa von Haefen
Int. J. Med. Sci. 2018; 15(7): 682-688. doi:10.7150/ijms.25393
[Abstract] [Full text] [PDF]

Research Paper
Inhibition of CRL-NEDD8 pathway as a new approach to enhance ATRA-induced differentiation of acute promyelocytic leukemia cells
Shuyuan Liu, Jinhua Wan, Yunyuan Kong, Yonglu Zhang, Lagen Wan, Zhanglin Zhang
Int. J. Med. Sci. 2018; 15(7): 674-681. doi:10.7150/ijms.23782
[Abstract] [Full text] [PDF]

Research Paper
ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells
Qianmei Chen, Lijun Mo, Xiangsheng Cai, Lili Wei, Zhengneng Xie, Hongwei Li, Jinlong Li, Zhiming Hu
Int. J. Med. Sci. 2018; 15(7): 666-673. doi:10.7150/ijms.23940
[Abstract] [Full text] [PDF]

New Trends in the Therapeutic Approach to Metastatic Colorectal Cancer
Julia Sánchez-Gundín, Ana María Fernández-Carballido, Lidia Martínez-Valdivieso, Dolores Barreda-Hernández, Ana Isabel Torres-Suárez
Int. J. Med. Sci. 2018; 15(7): 659-665. doi:10.7150/ijms.24453
[Abstract] [Full text] [PDF]

Research Paper
Impact of matrix metalloproteinase-11 gene polymorphisms upon the development and progression of hepatocellular carcinoma
Bin Wang, Chin-Jung Hsu, Hsiang-Lin Lee, Chia-Hsuan Chou, Chen-Ming Su, Shun-Fa Yang, Chih-Hsin Tang
Int. J. Med. Sci. 2018; 15(6): 653-658. doi:10.7150/ijms.23733
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Verteporfin inhibits YAP-induced bladder cancer cell growth and invasion via Hippo signaling pathway
Liang Dong, Fan Lin, Wanjun Wu, Yuchen Liu, Weiren Huang
Int. J. Med. Sci. 2018; 15(6): 645-652. doi:10.7150/ijms.23460
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
AMACR overexpression acts as a negative prognostic factor in oral squamous cell carcinoma
Hong-Lin He, Ying-En Lee, Min-Te Chang, Yow-Ling Shiue, Shih-Lun Chang, Tzu-Ju Chen, Chang-Ta Chiu
Int. J. Med. Sci. 2018; 15(6): 638-644. doi:10.7150/ijms.23291
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Resveratrol attenuates denervation-induced muscle atrophy due to the blockade of atrogin-1 and p62 accumulation
Yuka Asami, Miki Aizawa, Masakazu Kinoshita, Junji Ishikawa, Kunihiro Sakuma
Int. J. Med. Sci. 2018; 15(6): 628-637. doi:10.7150/ijms.22723
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Anti-biofilm and Anti-Virulence Efficacy of Celastrol Against Stenotrophomonas maltophilia
Hye-Rim Kim, Dongsup Lee, Yong-Bin Eom
Int. J. Med. Sci. 2018; 15(6): 617-627. doi:10.7150/ijms.23924
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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