International Journal of Medical Sciences

23 May 2013

ISSN 1449-1907

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International Journal of Biological Sciences

Journal of Cancer

Theranostics

Journal of Genomics

Editor-in-Chief: Dennis D. Taub, Ph.D.
Editor-in-Chief's Profile

Official impact factor is 2.244 according to the latest Journal Citation Report from Thomson Reuters.
Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
Full texts of articles appear in PubMed Central, Europe PMC, and PMC Canada.
High visibility of articles in the Internet.
(For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement.
This Journal is ranked very well according to SCImago in the area of Medicine ...details

Top cited papers:

DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 53
Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 99
Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 93
SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 167

The number of cancer survivors in the U.S. has increased from 3 million in 1971, when the National Cancer Act was enacted, to over 12 million today. Over 70% of children affected by cancer survive more than 10 years, and most are cured. Most cancer survivors are adults, with two-thirds of them 65 years of age or older and two-thirds alive at five years. The most common cancer diagnoses among survivors include breast, prostate and colorectal cancers. This review was conducted to better appreciate the challenges associated with cancer survivors and the opportunities healthcare providers have in making a difference for these patients.....details

In vitro, nitric oxide (NO) has been shown to have antimicrobial activity against a wide range of viruses, including influenza A virus. Therefore, we hypothesized that inhaled nitric oxide (iNO) would increase survival in vivo by reducing the viral load in C57Bl/6 mice infected with a lethal dose of influenza A/WSN/33 (H1N1; WSN/33) virus. NO was delivered to influenza-infected mice either continuously or intermittently at 80 or 160 ppm, respectively, using both prophylactic and post-infection treatment strategies. Murine survival and weight loss were assessed, and lung viral load was quantified via plaque assay. Here, we report that iNO administered prophylactically or post-influenza infection failed to improve survival of infected mice. ....details

The number of genetic association studies is increasing exponentially. Nonetheless, genetic association reports are prone to potential biases which may influence the reported outcome. We hypothesized that positive outcome for a determined polymorphism might be over-reported across genetic association studies analysing a small number of polymorphisms, when compared to studies analysing the same polymorphism together with a high number of other polymorphisms.We systematically reviewed published reports on the association of glutathione s-transferase (GST) single-nucleotide polymorphisms (SNPs) and cancer outcome....details

Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per treatment group. Resting metabolic rates (RMR), blood pressure, heart rates and a self-reported rating scale were determined at baseline and 75 min after oral ingestion of the test products in V-8 juice. ...details

Adverse event reports (AERs) submitted to the US Food and Drug Administration (FDA) were reviewed to confirm platinum agent-associated adverse events, and to clarify the rank-order of these drugs in terms of susceptibility. After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving cisplatin (CDDP), carboplatin (CBDCA), or oxaliplatin (L-OHP) were analyzed. Authorized pharmacovigilance tools were used for the quantitative detection of signals, i.e., drug-associated adverse events, including the proportional reporting ratio, the reporting odds ratio, the information component given by a Bayesian confidence propagation neural network, and the empirical Bayes geometric mean. ...details

International Journal of Medical Sciences Cover Page

Research Paper
A Survey of the FAERS Database Concerning the Adverse Event Profiles of α1-Adrenoreceptor Blockers for Lower Urinary Tract Symptoms
Koji Yoshimura, Kaori Kadoyama, Toshiyuki Sakaeda, Yoshio Sugino, Osamu Ogawa, Yasushi Okuno
Int. J. Med. Sci. 2013; 10(7): 864-869. doi:10.7150/ijms.5892
[Abstract] [Full text] [PDF]

Research Paper
Thyroid-Stimulating Hormone Is Significantly Associated with Bone Health Status in Men
Kok-Yong Chin, Soelaiman Ima-Nirwana, Isa Naina Mohamed, Amilia Aminuddin, Mohamad Hanapi Johari, Wan Zurinah Wan Ngah
Int. J. Med. Sci. 2013; 10(7): 857-863. doi:10.7150/ijms.5870
[Abstract] [Full text] [PDF]

Research Paper
Hemodynamic Reactivity to Laboratory Stressors in Healthy Subjects: Influence of Gender and Family History of Cardiovascular Diseases
Giovana M. S. Simoes, Bianca P. Campagnaro, Clarissa L. Tonini, Silvana S. Meyrelles, Fatima H. Sert Kuniyoshi, Elisardo C. Vasquez
Int. J. Med. Sci. 2013; 10(7): 848-856. doi:10.7150/ijms.5967
[Abstract] [Full text] [PDF]

Research Paper
Associations of MMP1, 3, 9 and TIMP3 Genes Polymorphism with Isolated Systolic Hypertension in Chinese Han Population
Rong Huang, Liehua Deng, AnNa Shen, Jian Liu, Hao Ren, Ding-Li Xu
Int. J. Med. Sci. 2013; 10(7): 840-847. doi:10.7150/ijms.5728
[Abstract] [Full text] [PDF]

Research Paper
Increased Levels of Macrophage Migration Inhibitory Factor in Patients with Familial Mediterranean Fever
Yusuf Savran, Ismail Sari, Didem Leyla Kozaci, Necati Gunay, Fatos Onen, Servet Akar
Int. J. Med. Sci. 2013; 10(7): 836-839. doi:10.7150/ijms.6116
[Abstract] [Full text] [PDF]

Research Paper
A Systematic Review and Meta-Analysis of Randomized Trials and Prospective Studies Comparing Covered and Bare Self-Expandable Metal Stents for the Treatment of Malignant Obstruction in the Digestive Tract
Zhiping Yang, Qiong Wu, Fang Wang, Xiaofei Ye, Xingshun Qi, Daiming Fan
Int. J. Med. Sci. 2013; 10(7): 825-835. doi:10.7150/ijms.5969
[Abstract] [Full text] [PDF]

Research Paper
Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 /Nuclear Factor-Kappa B Axis
Dongfang Yang, Jia Yuan, Gan Liu, Zhiyu Ling, Haiyan Zeng, Yunqing Chen, Yue Zhang, Qiang She, Xue Zhou
Int. J. Med. Sci. 2013; 10(7): 812-824. doi:10.7150/ijms.5931
[Abstract] [Full text] [PDF]

Research Paper
Areca Nut Chewing and Risk of Atrial Fibrillation in Taiwanese Men: A Nationwide Ecological Study
Wei-Chung Tsai, Chung-Yu Chen, Hsuan-Fu Kuo, Ming-Tsang Wu, Wei-Hua Tang, Chih-Sheng Chu, Tsung-Hsien Lin, Ho-Ming Su, Po-Chao Hsu, Shih-Jie Jhuo, Ming-Yen Lin, Kun-Tai Lee, Sheng-Hsiung Sheu, Wen-Ter Lai
Int. J. Med. Sci. 2013; 10(7): 804-811. doi:10.7150/ijms.5998
[Abstract] [Full text] [PDF]

Review
Data Mining of the Public Version of the FDA Adverse Event Reporting System
Toshiyuki Sakaeda, Akiko Tamon, Kaori Kadoyama, Yasushi Okuno
Int. J. Med. Sci. 2013; 10(7): 796-803. doi:10.7150/ijms.6048
[Abstract] [Full text] [PDF]

Research Paper
The Clinical Pattern of Knee Osteoarthritis in Jordan: A Hospital Based Study
Ziad M.Hawamdeh, Jihad M. Al-Ajlouni
Int. J. Med. Sci. 2013; 10(6): 790-795. doi:10.7150/ijms.5140
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
A Novel Semisynthetic Molecule Icaritin Stimulates Osteogenic Differentiation and Inhibits Adipogenesis of Mesenchymal Stem Cells
Hui Sheng, Xue-fei Rui, Chun-Jun Sheng, Wen-Jun Li, Xiao-Yun Cheng, Navina Priya Jhummon, Yong-Chun Yu, Shen Qu, Ge Zhang, Ling Qin
Int. J. Med. Sci. 2013; 10(6): 782-789. doi:10.7150/ijms.6084
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
Dunquan Xu, Wen Niu, Ying Luo, Bo Zhang, Manling Liu, Haiying Dong, Yi Liu, Zhichao Li
Int. J. Med. Sci. 2013; 10(6): 771-781. doi:10.7150/ijms.5906
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication
Identification of a Novel Nonsense Mutation in POLH in a Chinese Pedigree with Xeroderma Pigmentosum, Variant Type
Xiaoyan Liu, Xianning Zhang, Jianjun Qiao, Hong Fang
Int. J. Med. Sci. 2013; 10(6): 766-770. doi:10.7150/ijms.6095
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Correlation between Peripheral White Blood Cell Counts and Hyperglycemic Emergencies
Wei Xu, Hai-feng Wu, Shao-gang Ma, Feng Bai, Wen Hu, Yue Jin, Hong Liu
Int. J. Med. Sci. 2013; 10(6): 758-765. doi:10.7150/ijms.6155
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Is Stroke Volume Variation a Useful Preload Index in Liver Transplant Recipients? A Retrospective Analysis
Sung-Hoon Kim, Gyu-Sam Hwang, Seon-Ok Kim, Young-Kug Kim
Int. J. Med. Sci. 2013; 10(6): 751-757. doi:10.7150/ijms.6074
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication
Why Is Saline So Acidic (and Does It Really Matter?)
Benjamin AJ Reddi
Int. J. Med. Sci. 2013; 10(6): 747-750. doi:10.7150/ijms.5868
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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