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International Journal of Biological Sciences
Journal of Cancer
Theranostics
Journal of Genomics
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- Official impact factor is 2.065 (in 2013) and 2.244 (in 2012) according to the Journal Citation Report from Thomson Reuters.
- Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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Top cited papers:
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| Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details |
| A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details |
| The promoter is a major element in the expression cassette of gene therapy vectors. Optimal promoter selection can enhance target specificity and gene expression. Recently, we evaluated three different human elongation factor 1 alpha (EF1α) promoters. The three promoters were put into the same expression vector, pAC-luc, driving expression of the luciferase cDNA. The activity from one EF1α promoter (termed EF1α -3), obtained in a commercial vector, was markedly lower when tested in vitro (from 50 - 500 x) in four cell lines and in vivo in rat submandibular glands (~250 x). Sequence differences in the EF1α -3 promoter likely account for the activity differences seen. Investigators need to recognize that all promoters of the same name may not be equivalent in driving transgene expression. ...details |
| Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details |
Research Paper
King Cobra (Ophiophagus hannah) Venom L-Amino Acid Oxidase Induces Apoptosis in PC-3 Cells and Suppresses PC-3 Solid Tumor Growth in a Tumor Xenograft Mouse Model
Mui Li Lee, Shin Yee Fung, Ivy Chung, Jayalakshmi Pailoor, Swee Hung Cheah, Nget Hong Tan
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Late-onset Depression in the Absence of Stroke: Associated with Silent Brain Infarctions, Microbleeds and Lesion Locations
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Int. J. Med. Sci. 2014; 11(6): 578-586. doi:10.7150/ijms.8365
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Mutational Spectrum of the NKX2-5 Gene in Patients with Lone Atrial Fibrillation
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The Use of a Whole Animal Biophotonic Model as a Screen for the Angiogenic Potential of Estrogenic Compounds
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Int. J. Med. Sci. 2014; 11(6): 538-544. doi:10.7150/ijms.7896
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Int. J. Med. Sci. 2014; 11(5): 528-537. doi:10.7150/ijms.8220
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Association Study of ARL15 and CDH13 with T2DM in a Han Chinese Population
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Int. J. Med. Sci. 2014; 11(5): 522-527. doi:10.7150/ijms.8206
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Serum Hyperglycemia Might Be Not Related to Fat Composition of Diet and Vegetable Composition of Diet Might Improve Sugar Control in Taiwanese Diabetic Subjects
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Int. J. Med. Sci. 2014; 11(5): 515-521. doi:10.7150/ijms.8158
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Tuberculosis Disease Diagnosis Using Artificial Immune Recognition System
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Differential Expression Profile of Long Non-coding RNAs during Differentiation of Cardiomyocytes
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Int. J. Med. Sci. 2014; 11(5): 494-499. doi:10.7150/ijms.8842
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Identifying Hedgehog Signaling Specific MicroRNAs in Glioblastomas
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A Cell-Based Pharmacokinetics Assay for Evaluating Tubulin-Binding Drugs
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Sex-specific Association of the Zinc Finger Protein 259 rs2075290 Polymorphism and Serum Lipid Levels
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Int. J. Med. Sci. 2014; 11(5): 471-478. doi:10.7150/ijms.8489
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