International Journal of Medical Sciences

Impact factor
2.284

16 January 2019

ISSN 1449-1907

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Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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This Journal is ranked very well according to SCImago in the area of Medicine ...details

Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Laxmaiah Manchikanti et al. Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-Up. Cited by 95
DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 79
Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 146
Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 137
SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 283

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details

Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details

A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details

Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details

Research Paper
Correlation between genetic polymorphism of angiopoietin-2 gene and clinical aspects of rheumatoid arthritis
Chengqian Dai, Shu-Jui Kuo, Jin Zhao, Lulu Jin, Le Kang, Lihong Wang, Guohong Xu, Chih-Hsin Tang, Chen-Ming Su
Int. J. Med. Sci. 2019; 16(2): 331-336. doi:10.7150/ijms.30582
[Abstract] [Full text] [PDF]

Research Paper
A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia
Jingwen Sun, Jinjing Zhang, Yue Wang, Yan Li, Rui Zhang
Int. J. Med. Sci. 2019; 16(2): 324-330. doi:10.7150/ijms.27757
[Abstract] [Full text] [PDF]

Research Paper
Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock
Elliot Melendez, Jane E. Whitney, Jackson S. Norton, Melanie Silverman, Susanna Harju-Baker, Carmen Mikacenic, Mark M. Wurfel, W. Conrad Liles
Int. J. Med. Sci. 2019; 16(2): 318-323. doi:10.7150/ijms.27731
[Abstract] [Full text] [PDF]

Research Paper
Feasible Advantage of Bioactive/Bioresorbable Devices Made of Forged Composites of Hydroxyapatite Particles and Poly-L-lactide in Alveolar Bone Augmentation: A Preliminary Study
Shintaro Sukegawa, Hotaka Kawai, Keisuke Nakano, Takahiro Kanno, Kiyofumi Takabatake, Hitoshi Nagatsuka, Yoshihiko Furuki
Int. J. Med. Sci. 2019; 16(2): 311-317. doi:10.7150/ijms.27986
[Abstract] [Full text] [PDF]

Research Paper
Imbalance of erythropoiesis and iron metabolism in patients with thalassemia
Yumei Huang, Yu Lei, Rongrong Liu, Jiaodi Liu, Gaohui Yang, Zhifu Xiang, Yuzhen Liang, Yongrong Lai
Int. J. Med. Sci. 2019; 16(2): 302-310. doi:10.7150/ijms.27829
[Abstract] [Full text] [PDF]

Review
Circular RNA: a novel biomarker and therapeutic target for human cancers
Bo Lei, Zhiqiang Tian, Weiping Fan, Bing Ni
Int. J. Med. Sci. 2019; 16(2): 292-301. doi:10.7150/ijms.28047
[Abstract] [Full text] [PDF]

Research Paper
Non-alcoholic fatty liver disease is associated with low-grade albuminuria in men without diabetes mellitus
Seok Hui Kang, Kyu Hyang Cho, Jun Young Do
Int. J. Med. Sci. 2019; 16(2): 285-291. doi:10.7150/ijms.28264
[Abstract] [Full text] [PDF]

Research Paper
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men
Susan M. Graham, Junmei Chen, Jennie Le, Minhua Ling, Dominic W. Chung, W. Conrad Liles, José A. López
Int. J. Med. Sci. 2019; 16(2): 276-284. doi:10.7150/ijms.28110
[Abstract] [Full text] [PDF]

Research Paper
Platelet Reactivity And Circulating Platelet-Derived Microvesicles Are Differently Affected By P2Y₁₂ Receptor Antagonists
Bernadeta Chyrchel, Anna Drożdż, Dorota Długosz, Ewa Ł. Stępień, Andrzej Surdacki
Int. J. Med. Sci. 2019; 16(2): 264-275. doi:10.7150/ijms.28580
[Abstract] [Full text] [PDF]

Research Paper
Temporomandibular Disorders and Oral Features in Early Rheumatoid Arthritis Patients: An Observational Study
Vito Crincoli, Maria Grazia Anelli, Eleonora Quercia, Maria Grazia Piancino, Mariasevera Di Comite
Int. J. Med. Sci. 2019; 16(2): 253-263. doi:10.7150/ijms.28361
[Abstract] [Full text] [PDF]

Research Paper
Reliability of Preoperative Inguinal Sonography for Evaluating Patency of Processus Vaginalis in Pediatric Inguinal Hernia Patients
Jung-Man Namgoong, Won Yong Choi
Int. J. Med. Sci. 2019; 16(2): 247-252. doi:10.7150/ijms.28730
[Abstract] [Full text] [PDF]

Research Paper
MUC7 Level As A New Saliva Risk Factor For Dental Caries In Adult Patients
Anna K. Szkaradkiewicz-Karpińska, Anna Ronij, Olga Goślińska-Kuźniarek, Izabela Przybyłek, Andrzej Szkaradkiewicz
Int. J. Med. Sci. 2019; 16(2): 241-246. doi:10.7150/ijms.29027
[Abstract] [Full text] [PDF]

Research Paper
In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells
Daniel Roca-Lema, Olaia Martinez-Iglesias, Catalina Fernández de Ana Portela, Arturo Rodríguez-Blanco, Manuel Valladares-Ayerbes, Andrea Díaz-Díaz, Alba Casas-Pais, Cecilia Prego, Angélica Figueroa
Int. J. Med. Sci. 2019; 16(2): 231-240. doi:10.7150/ijms.28811
[Abstract] [Full text] [PDF]

Research Paper
A New Look at Causal Factors of Idiopathic Scoliosis: Altered Expression of Genes Controlling Chondroitin Sulfate Sulfation and Corresponding Changes in Protein Synthesis in Vertebral Body Growth Plates
Alla M. Zaydman, Elena L. Strokova, Alena O.Stepanova, Pavel P. Laktionov, Alexander I. Shevchenko, Vladimir M. Subbotin
Int. J. Med. Sci. 2019; 16(2): 221-230. doi:10.7150/ijms.29312
[Abstract] [Full text] [PDF]

Research Paper
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation
Ying-Hsien Huang, Hsing-Chun Kuo, Ya-Ling Yang, Feng-Sheng Wang
Int. J. Med. Sci. 2019; 16(2): 212-220. doi:10.7150/ijms.29930
[Abstract] [Full text] [PDF]

Review
Current status of endovascular treatment for dural arteriovenous fistulae in the anterior cranial fossa: A systematic literature review
Kan Xu, Tiefeng Ji, Chao Li, Jinlu Yu
Int. J. Med. Sci. 2019; 16(2): 203-211. doi:10.7150/ijms.29637
[Abstract] [Full text] [PDF]

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