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International Journal of Biological Sciences
Journal of Cancer
Theranostics
Journal of Genomics
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- Official impact factor is 2.065 (in 2013) and 2.244 (in 2012) according to the Journal Citation Report from Thomson Reuters.
- Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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Top cited papers:
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| We found 1. Multiple drugs are associated with pneumothorax; 2. Surfactants and oncology drugs account for most statistically distinctive associations with pneumothorax; 3. Pulmonary surfactants, pentamidine and nitric oxide have the largest statistical reporting associations 4. CBI may play a prominent role in reports of drug-associated pneumothorax. Conclusions: Disproportionality analysis (DA) can provide insights into the spontaneous reporting dependencies between drugs and pneumothorax. CBI assessment based on DA and Cornfield's inequality presents an additional novel option for the initial exploration of potential safety signals in PhV. ...details |
| Background Estrogen receptor-positive breast cancer tumors depend on estrogen signaling for their growth and replication and can be treated by anti-estrogen therapy with tamoxifen. Polymorphisms of the CYP2D6 and CYP2C19 genes are associated with an impaired response to tamoxifen. The study objective was to investigate the impact of genetic polymorphisms in CYP2D6 and CYP2C19 on the pharmacokinetics of tamoxifen and its metabolites in Spanish women with estrogen receptor-positive breast cancer who were candidates for tamoxifen therapy. Methods: We studied 90 women with estrogen receptor-positive breast cancer, using the AmpliChip CYP450 test to determine CYP2D6 and CYP2C19 gene variants. Plasma levels of tamoxifen and its metabolites were quantified by high-performance liquid chromatography....details |
| The US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS, formerly AERS) is a database that contains information on adverse event and medication error reports submitted to the FDA. Besides those from manufacturers, reports can be submitted from health care professionals and the public. The original system was started in 1969, but since the last major revision in 1997, reporting has markedly increased. Data mining algorithms have been developed for the quantitative detection of signals from such a large database, where a signal means a statistical association between a drug and an adverse event or a drug-associated adverse event, including the proportional reporting ratio (PRR), the reporting odds ratio (ROR), the information component (IC), and the empirical Bayes geometric mean (EBGM). ...details |
Short Research Communication
All Human EF1α Promoters Are Not Equal: Markedly Affect Gene Expression in Constructs from Different Sources
Changyu Zheng, Bruce J. Baum
Int. J. Med. Sci. 2014; 11(5): 404-408. doi:10.7150/ijms.8033
[Abstract]
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[PDF] Research Paper
Different Isolation Methods Alter the Gene Expression Profiling of Adipose Derived Stem Cells
Nareshwaran Gnanasegaran, Vijayendran Govindasamy, Sabri Musa, Noor Hayaty Abu Kasim
Int. J. Med. Sci. 2014; 11(4): 391-403. doi:10.7150/ijms.7697
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[PDF] Letter To Editor
Mutations in PRSS1 Put into Perspective
Philipp G. Sand
Int. J. Med. Sci. 2014; 11(4): 389-390. doi:10.7150/ijms.7613
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Int. J. Med. Sci. 2014; 11(4): 381-388. doi:10.7150/ijms.7069
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Endothelin-1 Promotes Cardiomyocyte Terminal Differentiation in the Developing Heart via Heightened DNA Methylation
Alexandra Paradis, Daliao Xiao, Jianjun Zhou, Lubo Zhang
Int. J. Med. Sci. 2014; 11(4): 373-380. doi:10.7150/ijms.7802
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Decreased Activities of Apolipoprotein M Promoter Are Associated with the Susceptibility to Coronary Artery Diseases
Lu Zheng, Guanghua Luo, Jun Zhang, Qinfeng Mu, Yuanping Shi, Maria Berggren-Söderlund, Peter Nilsson-Ehle, Xiaoying Zhang, Ning Xu
Int. J. Med. Sci. 2014; 11(4): 365-372. doi:10.7150/ijms.7696
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Osteoclastogenic Potential of Peripheral Blood Mononuclear Cells in Cleidocranial Dysplasia
Maria Felicia Faienza, Annamaria Ventura, Laura Piacente, Maria Ciccarelli, Margherita Gigante, Loreto Gesualdo, Silvia Colucci, Luciano Cavallo, Maria Grano, Giacomina Brunetti
Int. J. Med. Sci. 2014; 11(4): 356-364. doi:10.7150/ijms.7793
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The Relationships between Thyroid Hormones and Thyroid-stimulating Hormone with Lipid Profile in Euthyroid Men
Kok-Yong Chin, Soelaiman Ima-Nirwana, Isa Naina Mohamed, Amilia Aminuddin, Mohamad Hanapi Johari, Wan Zurinah Wan Ngah
Int. J. Med. Sci. 2014; 11(4): 349-355. doi:10.7150/ijms.7104
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[PMC] Short Research Communication
Glial Scar Formation Occurs in the Human Brain after Ischemic Stroke
Lijie Huang, Zhe-Bao Wu, Qichuan ZhuGe, WeiMing Zheng, Bei Shao, Brian Wang, Fen Sun, Kunlin Jin
Int. J. Med. Sci. 2014; 11(4): 344-348. doi:10.7150/ijms.8140
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Ulinastatin Preconditioning Attenuates Inflammatory Reaction of Hepatic Ischemia Reperfusion Injury in Rats via High Mobility Group Box 1(HMGB1) Inhibition
Ying Tong, Zhaohui Tang, Tian Yang, Yuting Yang, Liqun Yang, Weixing Shen, Weixin Chen
Int. J. Med. Sci. 2014; 11(4): 337-343. doi:10.7150/ijms.7861
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Antibacterial Activity of a Cardanol from Thai Apis mellifera Propolis
Pattaraporn Boonsai, Preecha Phuwapraisirisan, Chanpen Chanchao
Int. J. Med. Sci. 2014; 11(4): 327-336. doi:10.7150/ijms.7373
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Genetic Polymorphisms in SLC23A2 as Predictive Biomarkers of Severe Acute Toxicities after Treatment with a Definitive 5-Fluorouracil/Cisplatin-Based Chemoradiotherapy in Japanese Patients with Esophageal Squamous Cell Carcinoma
Tetsuya Minegaki, Akiko Kuwahara, Motohiro Yamamori, Tsutomu Nakamura, Tatsuya Okuno, Ikuya Miki, Hideaki Omatsu, Takao Tamura, Midori Hirai, Takeshi Azuma, Toshiyuki Sakaeda, Kohshi Nishiguchi
Int. J. Med. Sci. 2014; 11(4): 321-326. doi:10.7150/ijms.7654
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Two-Year Follow-Up Results of Fluoroscopic Cervical Epidural Injections in Chronic Axial or Discogenic Neck Pain: A Randomized, Double-Blind, Controlled Trial
Laxmaiah Manchikanti, Kimberly A. Cash, Vidyasagar Pampati, Yogesh Malla
Int. J. Med. Sci. 2014; 11(4): 309-320. doi:10.7150/ijms.8069
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Effects of ECM Protein Mimetics on Adhesion and Proliferation of Chorion Derived Mesenchymal Stem Cells
Ji-Hyun Kim, Dong Wook Jekarl, Myungshin Kim, Eun-Jee Oh, Yonggoo Kim, In Yang Park, Jong Chul Shin
Int. J. Med. Sci. 2014; 11(3): 298-308. doi:10.7150/ijms.6672
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The perception of the Illness with Subsequent Outcome Measure in More Favorable in Continuos Peritoneal Dialysis vs Hemodialysis in the Framework of Appraisal Model of Stress
Zbigniew Nowak, Krzysztof Laudański
Int. J. Med. Sci. 2014; 11(3): 291-297. doi:10.7150/ijms.5431
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Protective Effect of Quercetin against Oxidative Stress and Brain Edema in an Experimental Rat Model of Subarachnoid Hemorrhage
Yu-shu Dong, Ju-lei Wang, Da-yun Feng, Huai-zhou Qin, Hua Wen, Zhong-min Yin, Guo-dong Gao, Chuan Li
Int. J. Med. Sci. 2014; 11(3): 282-290. doi:10.7150/ijms.7634
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