International Journal of Medical Sciences

Impact factor
2.284

18 October 2018

ISSN 1449-1907

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Theranostics

Journal of Cancer

International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Oncomedicine

Journal of Biomedicine

Nanotheranostics

Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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This Journal is ranked very well according to SCImago in the area of Medicine ...details

Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Laxmaiah Manchikanti et al. Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-Up. Cited by 95
DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 79
Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 146
Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 137
SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 283

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details

Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details

A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details

Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details

Research Paper
Effect of mistletoe on endometrial stromal cell survival and vascular endothelial growth factor expression in patients with endometriosis
Jeong Min Moon, Youn-Jee Chung, Boah Chae, Hee Jin Kang, Hyun Hee Cho, Jang Heub Kim, Mee-Ran Kim
Int. J. Med. Sci. 2018; 15(13): 1530-1536. doi:10.7150/ijms.28470
[Abstract] [Full text] [PDF]

Research Paper
Comparisons of Pressure-controlled Ventilation with Volume Guarantee and Volume-controlled 1:1 Equal Ratio Ventilation on Oxygenation and Respiratory Mechanics during Robot-assisted Laparoscopic Radical Prostatectomy: a Randomized-controlled Trial
Min-Soo Kim, Sarah Soh, So Yeon Kim, Min sup Song, Jin Ha Park
Int. J. Med. Sci. 2018; 15(13): 1522-1529. doi:10.7150/ijms.28442
[Abstract] [Full text] [PDF]

Research Paper
Ethanol Extract from Brucea Javanica Seed Inhibits Angiogenesis Mediated by Platelet Derived Growth Factor Receptor-beta
Xiaotong Wang, Yunyun Li, Yan Mou, Zhen Yue, Haiying Zhang, Ronggui Li, Hongxia Sun
Int. J. Med. Sci. 2018; 15(13): 1517-1521. doi:10.7150/ijms.28337
[Abstract] [Full text] [PDF]

Research Paper
Simvastatin Protects Heart from Pressure Overload Injury by Inhibiting Excessive Autophagy
Feifei Su, Miaoqian Shi, Jian Zhang, Qiangsun Zheng, Dongwei Zhang, Wei Zhang, Haichang Wang, Xue Li
Int. J. Med. Sci. 2018; 15(13): 1508-1516. doi:10.7150/ijms.28106
[Abstract] [Full text] [PDF]

Research Paper
NDRG1 Downregulates ATF3 and Inhibits Cisplatin-Induced Cytotoxicity in Lung Cancer A549 Cells
Aolin Du, Yufeng Jiang, Chuifeng Fan
Int. J. Med. Sci. 2018; 15(13): 1502-1507. doi:10.7150/ijms.28055
[Abstract] [Full text] [PDF]

Research Paper
Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term Cultures
Federica Facchin, Eva Bianconi, Miriam Romano, Alessia Impellizzeri, Francesco Alviano, Margherita Maioli, Silvia Canaider, Carlo Ventura
Int. J. Med. Sci. 2018; 15(13): 1486-1501. doi:10.7150/ijms.27181
[Abstract] [Full text] [PDF]

Research Paper
Influence of DNA methylation on the expression of OPG/RANKL in primary osteoporosis
Peng Wang, Yanming Cao, Dongxiang Zhan, Ding Wang, Bin Wang, Yamei Liu, Gang Li, Wei He, Haibin Wang, Liangliang Xu
Int. J. Med. Sci. 2018; 15(13): 1480-1485. doi:10.7150/ijms.27333
[Abstract] [Full text] [PDF]

Research Paper
Borrelia burgdorferi basic membrane protein A stimulates murine macrophage to secrete specific chemokines
Yun Peng, Zhang Liang, Aihua Liu, Erhua Li, Xiting Dai, Ruolan Bai, Zhenhua Ji, Miaomiao Jian, Mingbiao Ma, Lvyan Tao, Fukai Bao, Feng Wang, YunFeng Bi, Zhe Ding, Abi Manzama-Esso
Int. J. Med. Sci. 2018; 15(13): 1473-1479. doi:10.7150/ijms.26657
[Abstract] [Full text] [PDF]

Erratum
LncRNA AFAP1-AS Functions as a Competing Endogenous RNA to Regulate RAP1B Expression by sponging miR-181a in the HSCR: Erratum
Guanglin Chen, Lei Peng, Zhongxian Zhu, Chunxia Du, Ziyang Shen, Rujin Zang, Yang Su, Yankai Xia, Weibing Tang
Int. J. Med. Sci. 2018; 15(13): 1472. doi:10.7150/ijms.29742
[Abstract] [Full text] [PDF]

Research Paper
Effects of polymethylmethacrylate on the stability of screw fixation in mandibular angle fractures: A study on sheep mandibles
Abdulkadir Burak Cankaya, Metin Berk Kasapoglu, Mehmet Ali Erdem, Cetin Kasapoglu
Int. J. Med. Sci. 2018; 15(13): 1466-1471. doi:10.7150/ijms.26697
[Abstract] [Full text] [PDF]

Research Paper
Mechanical Properties and Porosity of Acrylic Cement Bone Loaded with Alendronate Powder
Guo-Xin Qu, Zhi-Min Ying, Chen-Chen Zhao, Shi-Gui Yan, Xun-Zi Cai
Int. J. Med. Sci. 2018; 15(13): 1458-1465. doi:10.7150/ijms.27759
[Abstract] [Full text] [PDF]

Research Paper
Plasmodium falciparum Treated with Artemisinin-based Combined Therapy Exhibits Enhanced Mutation, Heightened Cortisol and TNF-α Induction
Abel Olusola Idowu, Sanjib Bhattacharyya, Steve Gradus, Wellington Oyibo, Zenas George, Carolyn Black, Joseph Igietseme, Anthony Ajayi Azenabor
Int. J. Med. Sci. 2018; 15(13): 1449-1457. doi:10.7150/ijms.27350
[Abstract] [Full text] [PDF]

Review
Biology of MiR-17-92 Cluster and Its Progress in Lung Cancer
Xinju Zhang, Yanli Li, Pengfei Qi, Zhongliang Ma
Int. J. Med. Sci. 2018; 15(13): 1443-1448. doi:10.7150/ijms.27341
[Abstract] [Full text] [PDF]

Research Paper
Role of Sirolimus in renal tubular apoptosis in response to unilateral ureteral obstruction
Mei Yang, Yang-yang Zhuang, Wei-wei Wang, Hai-ping Zhu, Yan-jie Zhang, Sao-ling Zheng, Yi-Rrong Yang, Bi-Cheng Chen, Peng Xia, Yan Zhang
Int. J. Med. Sci. 2018; 15(13): 1433-1442. doi:10.7150/ijms.26954
[Abstract] [Full text] [PDF]

Research Paper
Administration of CoCl₂ Improves Functional Recovery in a Rat Model of Sciatic Nerve Transection Injury
Shuai An, Meng Zhou, Zheng Li, Mingli Feng, Guanglei Cao, Shibao Lu, Limin Liu
Int. J. Med. Sci. 2018; 15(13): 1423-1432. doi:10.7150/ijms.27867
[Abstract] [Full text] [PDF]

Review
Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis
Zhengqiang Li, Zhimin Xu, Congcong Duan, Weiwei Liu, Jingchun Sun, Bing Han
Int. J. Med. Sci. 2018; 15(12): 1415-1422. doi:10.7150/ijms.26741
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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