International Journal of Medical Sciences
Official Impact Factor

17 April 2014

ISSN 1449-1907 News feeds of published articles

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Theranostics

Journal of Genomics

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Editor-in-Chief: Dennis D. Taub, Ph.D.
Editor-in-Chief's Profile
  • Official impact factor is 2.065 (in 2013) and 2.244 (in 2012) according to the Journal Citation Report from Thomson Reuters.
  • Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
  • Full texts of articles appear in PubMed Central, Europe PMC, and PMC Canada.
  • High visibility of articles over the Internet.
  • (For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement.
  • This Journal is ranked very well according to SCImago in the area of Medicine ...details

Top cited papers:

Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
The promoter is a major element in the expression cassette of gene therapy vectors. Optimal promoter selection can enhance target specificity and gene expression. Recently, we evaluated three different human elongation factor 1 alpha (EF1α) promoters. The three promoters were put into the same expression vector, pAC-luc, driving expression of the luciferase cDNA. The activity from one EF1α promoter (termed EF1α -3), obtained in a commercial vector, was markedly lower when tested in vitro (from 50 - 500 x) in four cell lines and in vivo in rat submandibular glands (~250 x). Sequence differences in the EF1α -3 promoter likely account for the activity differences seen. Investigators need to recognize that all promoters of the same name may not be equivalent in driving transgene expression. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details

International Journal of Medical Sciences Cover Page

Research Paper
TMPRSS6 rs855791 Polymorphism Influences the Susceptibility to Iron Deficiency Anemia in Women at Reproductive Age
Sung-Nan Pei, Ming-Chun Ma, Huey-Ling You, Hung-Chun Fu, Ching-Yuan Kuo, Kun-Ming Rau, Ming-Chung Wang, Chien-Te Lee
Int. J. Med. Sci. 2014; 11(6): 614-619. doi:10.7150/ijms.8582
[Abstract] [Full text] [PDF]

Research Paper
The Expression of Toll-like Receptor 8 and Its Relationship with VEGF and Bcl-2 in Cervical Cancer
Yun Zhang, Heng Yang, Prince Amoah Barnie, Peifang Yang, Zhaoliang Su, Jianguo Chen, Zhijun Jiao, Liwei Lu, Shengjun Wang, Huaxi Xu
Int. J. Med. Sci. 2014; 11(6): 608-613. doi:10.7150/ijms.8428
[Abstract] [Full text] [PDF]

Research Paper
Energy and Nutritional Composition of Tiger Milk Mushroom (Lignosus tigris Chon S. Tan) Sclerotia and the Antioxidant Activity of Its Extracts
Hui-Yeng Yeannie Yap, Azlina Abdul Aziz, Shin-Yee Fung, Szu-Ting Ng, Chon-Seng Tan, Nget-Hong Tan
Int. J. Med. Sci. 2014; 11(6): 602-607. doi:10.7150/ijms.8341
[Abstract] [Full text] [PDF]

Research Paper
King Cobra (Ophiophagus hannah) Venom L-Amino Acid Oxidase Induces Apoptosis in PC-3 Cells and Suppresses PC-3 Solid Tumor Growth in a Tumor Xenograft Mouse Model
Mui Li Lee, Shin Yee Fung, Ivy Chung, Jayalakshmi Pailoor, Swee Hung Cheah, Nget Hong Tan
Int. J. Med. Sci. 2014; 11(6): 593-601. doi:10.7150/ijms.8096
[Abstract] [Full text] [PDF]

Research Paper
Late-onset Depression in the Absence of Stroke: Associated with Silent Brain Infarctions, Microbleeds and Lesion Locations
Ri-Han Wu, Chao Feng, Yu Xu, Ting Hua, Xue-Yuan Liu, Min Fang
Int. J. Med. Sci. 2014; 11(6): 587-592. doi:10.7150/ijms.8025
[Abstract] [Full text] [PDF]

Research Paper
Tanshinone IIA Attenuates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/ Angiotensin-(1-7) Axis in Rats
Huajie Wu, Yan Li, Yanxia Wang, Dunquan Xu, Congcong Li, Manling Liu, Xin Sun, Zhichao Li
Int. J. Med. Sci. 2014; 11(6): 578-586. doi:10.7150/ijms.8365
[Abstract] [Full text] [PDF]

Research Paper
Inhibition of MAPKs, Myc/Max, NFκB, and Hypoxia Pathways by Phyllanthus Prevents Proliferation, Metastasis and Angiogenesis in Human Melanoma (MeWo) Cancer Cell Line
Yin-Quan Tang, Indu Bala Jaganath, Rishya Manikam, Shamala Devi Sekaran
Int. J. Med. Sci. 2014; 11(6): 564-577. doi:10.7150/ijms.7704
[Abstract] [Full text] [PDF]

Research Paper
Mutational Spectrum of the NKX2-5 Gene in Patients with Lone Atrial Fibrillation
Hong Yu, Jia-Hong Xu, Hao-Ming Song, Lan Zhao, Wen-Jun Xu, Juan Wang, Ruo-Gu Li, Lei Xu, Wei-Feng Jiang, Xing-Biao Qiu, Jin-Qi Jiang, Xin-Kai Qu, Xu Liu, Wei-Yi Fang, Jin-Fa Jiang, Yi-Qing Yang
Int. J. Med. Sci. 2014; 11(6): 554-563. doi:10.7150/ijms.8407
[Abstract] [Full text] [PDF]

Research Paper
The Use of a Whole Animal Biophotonic Model as a Screen for the Angiogenic Potential of Estrogenic Compounds
Ramey C Youngblood, Marcus McGee, Jean M Feugang, Scott T Willard, Peter L Ryan
Int. J. Med. Sci. 2014; 11(6): 545-553. doi:10.7150/ijms.6994
[Abstract] [Full text] [PDF]

Short Research Communication
Senescence Affects Endothelial Cells Susceptibility to Dengue Virus Infection
Sazaly AbuBakar, Meng-Hooi Shu, Jefree Johari, Pooi-Fong Wong
Int. J. Med. Sci. 2014; 11(6): 538-544. doi:10.7150/ijms.7896
[Abstract] [Full text] [PDF]

Research Paper
Rutin, a Flavonoid and Principal Component of Saussurea Involucrata, Attenuates Physical Fatigue in a Forced Swimming Mouse Model
Kang-Yi Su, Chao Yuan Yu, Yue-Wen Chen, Yi-Tsau Huang, Chun-Ting Chen, Hsueh-Fu Wu, Yi-Lin Sophia Chen
Int. J. Med. Sci. 2014; 11(5): 528-537. doi:10.7150/ijms.8220
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Association Study of ARL15 and CDH13 with T2DM in a Han Chinese Population
Yiping Li, Ying Yang, Yueting Yao, Xianli Li, Li Shi, Ying Zhang, Yuxin Xiong, Man Yan, Yufeng Yao, Chunjie Xiao
Int. J. Med. Sci. 2014; 11(5): 522-527. doi:10.7150/ijms.8206
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Serum Hyperglycemia Might Be Not Related to Fat Composition of Diet and Vegetable Composition of Diet Might Improve Sugar Control in Taiwanese Diabetic Subjects
Yi-Cheng Hou, Ya-Lin Chang, Shi-Ching Kuo, Chih-Fan Chiang, Cheng-Yang Chiang, Yu-Fang Lin, Pei-Chen Weng, Fang-Ching Hu, Jing-Hui Wu, Chien-Han Lai
Int. J. Med. Sci. 2014; 11(5): 515-521. doi:10.7150/ijms.8158
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Tuberculosis Disease Diagnosis Using Artificial Immune Recognition System
Shahaboddin Shamshirband, Somayeh Hessam, Hossein Javidnia, Mohsen Amiribesheli, Shaghayegh Vahdat, Dalibor Petković, Abdullah Gani, Miss Laiha Mat Kiah
Int. J. Med. Sci. 2014; 11(5): 508-514. doi:10.7150/ijms.8249
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Differential Expression Profile of Long Non-coding RNAs during Differentiation of Cardiomyocytes
Shasha Zhu, Xiaoshan Hu, Shuping Han, Zhangbin Yu, Yuzhu Peng, Jingai Zhu, Xuehua Liu, Lingmei Qian, Chun Zhu, Mengmeng Li, Guixian Song, Xirong Guo
Int. J. Med. Sci. 2014; 11(5): 500-507. doi:10.7150/ijms.7849
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Comparison of Methods for the Extraction of DNA from Formalin-Fixed, Paraffin-Embedded Archival Tissues
Burcu Sengüven, Emre Baris, Tulin Oygur, Mehmet Berktas
Int. J. Med. Sci. 2014; 11(5): 494-499. doi:10.7150/ijms.8842
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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