International Journal of Medical Sciences

Impact factor
2.399

19 August 2017

ISSN 1449-1907 News feeds of published articles

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new Impact factor is 2.399 according to 2017 release of Journal Citation Reports®. Congratulations!

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Association of Maternal Serum 25-hydroxyvitamin D Concentrations in Second Trimester with Delivery Mode in A Chinese Population
Yingdi Yuan, Heng Liu, Chenbo Ji, Xirong Guo, Lingmin Hu, Juan Wen, Manhong Cai
Int. J. Med. Sci. 2017; 14(10): 1008-1014. doi:10.7150/ijms.20337
[Abstract] [Full text] [PDF]

Research Paper
IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis
Wenming Wang, Xiaoling Yu, Chao Wu, Hongzhong Jin
Int. J. Med. Sci. 2017; 14(10): 1002-1007. doi:10.7150/ijms.20809
[Abstract] [Full text] [PDF]

Research Paper
Comparison of the Analgesic Properties of Sevoflurane and Desflurane Using Surgical Pleth Index at Equi-Minimum Alveolar Concentration
Kyoungho Ryu, Keulame Song, Jia Kim, Eugene Kim, Seong-Hyop Kim
Int. J. Med. Sci. 2017; 14(10): 994-1001. doi:10.7150/ijms.20291
[Abstract] [Full text] [PDF]

Research Paper
Kaempferol Inhibits the Invasion and Migration of Renal Cancer Cells through the Downregulation of AKT and FAK Pathways
Tung-Wei Hung, Pei-Ni Chen, Hsu-Chen Wu, Sheng-Wen Wu, Pao-Yu Tsai, Yih-Shou Hsieh, Horng-Rong Chang
Int. J. Med. Sci. 2017; 14(10): 984-993. doi:10.7150/ijms.20336
[Abstract] [Full text] [PDF]

Research Paper
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis
Hao Wang, Jingdong Li, Qiyang Han, Fei Yang, Yu Xiao, Meng Xiao, Yingchun Xu, Longxiang Su, Na Cui, Dawei Liu
Int. J. Med. Sci. 2017; 14(10): 977-983. doi:10.7150/ijms.20212
[Abstract] [Full text] [PDF]

Research Paper
The Effects of Perioperative Anesthesia and Analgesia on Immune Function in Patients Undergoing Breast Cancer Resection: A Prospective Randomized Study
Jin Sun Cho, Mi-Hyang Lee, Seung Il Kim, Seho Park, Hyung Seok Park, Ein Oh, Jong Ho Lee, Bon-Nyeo Koo
Int. J. Med. Sci. 2017; 14(10): 970-976. doi:10.7150/ijms.20064
[Abstract] [Full text] [PDF]

Research Paper
Genotoxicity of a Low-Dose Nitrosamine Mixture as Drinking Water Disinfection Byproducts in NIH3T3 Cells
Hai-yan Wang, Ming Qin, Lei Dong, Jia-ying Lv, Xia Wang
Int. J. Med. Sci. 2017; 14(10): 961-969. doi:10.7150/ijms.20121
[Abstract] [Full text] [PDF]

Research Paper
Effects of dexmedetomidine in combination with fentanyl-based intravenous patient-controlled analgesia on pain attenuation after open gastrectomy in comparison with conventional thoracic epidural and fentanyl-based intravenous patient-controlled analgesia
Na Young Kim, Tae Dong Kwon, Sun Joon Bai, Sung Hoon Noh, Jung Hwa Hong, Haeyeon Lee, Ki-Young Lee
Int. J. Med. Sci. 2017; 14(10): 951-960. doi:10.7150/ijms.20347
[Abstract] [Full text] [PDF]

Research Paper
Effects of Hypobaric Hypoxia on Rat Retina and Protective Response of Resveratrol to the Stress
Xiaorong Xin, Hong Dang, Xiaojing Zhao, Haohao Wang
Int. J. Med. Sci. 2017; 14(10): 943-950. doi:10.7150/ijms.19391
[Abstract] [Full text] [PDF]

Research Paper
miR-224 Controls Human Colorectal Cancer Cell Line HCT116 Proliferation by Targeting Smad4
Jinzhe Zhou, Muren Hu, Fei Wang, Meiyi Song, Qi Huang, Bujun Ge
Int. J. Med. Sci. 2017; 14(10): 937-942. doi:10.7150/ijms.19565
[Abstract] [Full text] [PDF]

Research Paper
Thrombospondin-1 Gene Deficiency Worsens the Neurological Outcomes of Traumatic Brain Injury in Mice
Chongjie Cheng, Zhanyang Yu, Song Zhao, Zhengbu Liao, Changhong Xing, Yinghua Jiang, Yong-Guang Yang, Michael J. Whalen, Eng H. Lo, Xiaochuan Sun, Xiaoying Wang
Int. J. Med. Sci. 2017; 14(10): 927-936. doi:10.7150/ijms.18812
[Abstract] [Full text] [PDF]

Research Paper
Identification and Characteristics of Time-Related Shifts in Suicide-Related Event Frequency During Smoking Cessation Treatment with Varenicline
Hayato Akimoto, Haruna Wakiyama, Shinji Oshima, Akio Negishi, Kousuke Ohara, Sachihiko Numajiri, Mitsuyoshi Okita, Shigeru Ohshima, Naoko Inoue, Daisuke Kobayashi
Int. J. Med. Sci. 2017; 14(10): 920-926. doi:10.7150/ijms.19877
[Abstract] [Full text] [PDF]

Research Paper
Gender-dimorphic effects of adipose-derived stromal vascular fractions on HUVECs exposed to oxidative stress
Soyeon Lim, Il-Kwon Kim, Jung-Won Choi, Hyang-Hee Seo, Kyu Hee Lim, Seahyoung Lee, Hoon-Bum Lee, Sang Woo Kim, Ki-Chul Hwang
Int. J. Med. Sci. 2017; 14(9): 911-919. doi:10.7150/ijms.19998
[Abstract] [Full text] [PDF]

Research Paper
Effect of YAP Inhibition on Human Leukemia HL-60 Cells
Min Chen, Jian Wang, Shi-Fei Yao, Yi Zhao, Lu Liu, Lian-Wen Li, Ting Xu, Liu-Gen Gan, Chun-Lan Xiao, Zhi-Ling Shan, Liang Zhong, Bei-Zhong Liu
Int. J. Med. Sci. 2017; 14(9): 902-910. doi:10.7150/ijms.19965
[Abstract] [Full text] [PDF]

Research Paper
Amelioration of estrogen-deficiency-induced obesity by Ocimum gratissimum
Pei-Yu Chao, Tsay-I Chiang, I-Chang Chang, Fang-Ling Tsai, Hsueh-Hui Lee, Kuanghui Hsieh, Yung-Wei Chiu, Te-Jen Lai, Jer-Yuh Liu, Li-Sung Hsu, Yang-Chia Shih
Int. J. Med. Sci. 2017; 14(9): 896-901. doi:10.7150/ijms.19933
[Abstract] [Full text] [PDF]

Research Paper
Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure
Luis M. Pérez-Belmonte, Inmaculada Moreno-Santos, Juan J. Gómez-Doblas, José M. García-Pinilla, Luis Morcillo-Hidalgo, Lourdes Garrido-Sánchez, Concepción Santiago-Fernández, María G. Crespo-Leiro, Fernando Carrasco-Chinchilla, Pedro L. Sánchez-Fernández, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro
Int. J. Med. Sci. 2017; 14(9): 891-895. doi:10.7150/ijms.19854
[Abstract] [Full text] [PDF]

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