International Journal of Medical Sciences

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21 April 2019

ISSN 1449-1907 News feeds of published articles

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Journal of Genomics



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Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of these polysaccharide-rich extracts in LoVo and HT-29 human colon cancer cells. The in vitro effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Moreover, the effect on anchorage independent-cell growth was also determined. Our results showed that TV and GF extracts did inhibit human colon cell proliferation and induce cytotoxicity.. ...details
A number of biomaterials have been developed, some of which already enjoy widespread clinic use. We have devised a new honeycomb tricalcium phosphate (TCP) containing through-and-through holes of various diameters to control cartilage and bone formation. However, the way in which the geometric structure of the honeycomb TCP controls cartilage and bone tissue formation separately remains unknown. In addition, an association has been reported between bone formation and angiogenesis. Therefore, in the present study, we investigated the relationship between angiogenesis and various hole diameters in our honeycomb TCP over time in a rat ectopic hard tissue formation model.. ...details

Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste and smell, dental sensitivity.

The aim of this observational study was to investigate the prevalence of TMD symptoms and signs as well as oral implications in patients with Early Rheumatoid Arthritis (ERA), that is a RA diagnosed within 12 months, compared with a control group.

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Research Paper
Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells
Chengbo Wang, Keyan Li, Yingli Men, Cong Ding, Juan Du, Taotao Liang, Zhenyu Ji, Lixiang Chen, Ting Wang, Qiaozhen Kang
Int. J. Med. Sci. 2019; 16(4): 529-536. doi:10.7150/ijms.27401
[Abstract] [Full text] [PDF]

Research Paper
Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma
Ann Marie Mongan, Niamh Lynam-Lennon, Suzanne L Doyle, Rory Casey, Eibhlin Carr, Aoife Cannon, Melissa J Conroy, Graham P Pidgeon, Lorraine Brennan, Joanne Lysaght, John V. Reynolds, Jacintha O'Sullivan
Int. J. Med. Sci. 2019; 16(4): 519-528. doi:10.7150/ijms.29296
[Abstract] [Full text] [PDF]

Circular RNAs: Novel Promising Biomarkers in Ocular Diseases
Nan Guo, Xiu-fen Liu, Om Prakash Pant, Dan-Dan Zhou, Ji-long Hao, Cheng-wei Lu
Int. J. Med. Sci. 2019; 16(4): 513-518. doi:10.7150/ijms.29750
[Abstract] [Full text] [PDF]

Engineering of Human Corneal Endothelial Cells In Vitro
Qin Zhu, Yingting Zhu, Sean Tighe, Yongsong Liu, Min Hu
Int. J. Med. Sci. 2019; 16(4): 507-512. doi:10.7150/ijms.30759
[Abstract] [Full text] [PDF]

Research Paper
Intrauterine Fetal and Neonatal Death between Small for Date and Non-Small for Date in Small for Gestational Age Infants
Toshiya Itoh, Yoshio Matsuda, Hiroaki Itoh, Masaki Ogawa, Kemal Sasaki, Naohiro Kanayama
Int. J. Med. Sci. 2019; 16(4): 501-506. doi:10.7150/ijms.31153
[Abstract] [Full text] [PDF]

Research Paper
Anti-Cancer Effects of Sulfasalazine and Vitamin E Succinate in MDA-MB 231 Triple-Negative Breast Cancer Cells
Chyou-Wei Wei, Yung-Luen Yu, Ji-Ying Lu, Yu-Ting Hung, Hsiao-Chun Liu, Giou-Teng Yiang
Int. J. Med. Sci. 2019; 16(4): 494-500. doi:10.7150/ijms.30380
[Abstract] [Full text] [PDF]

Research Paper
A 3D Printed Porous Titanium Alloy Rod with Diamond Crystal Lattice for Treatment of the Early-Stage Femoral Head Osteonecrosis in Sheep
Cairu Wang, Da Liu, Qingyun Xie, Jinbiao Liu, Shaolin Deng, Kai Gong, Chen Huang, Li Yin, Meiming Xie, Zheng Guo, Wei Zheng
Int. J. Med. Sci. 2019; 16(3): 486-493. doi:10.7150/ijms.30832
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Airway Microbiome in Different Inflammatory Phenotypes of Asthma: A Cross-Sectional Study in Northeast China
Zhiqiang Pang, Guoqiang Wang, Peter Gibson, Xuewa Guan, Weijie Zhang, Ruipeng Zheng, Fang Chen, Ziyan Wang, Fang Wang
Int. J. Med. Sci. 2019; 16(3): 477-485. doi:10.7150/ijms.29433
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Hes3 Enhances the Malignant Phenotype of Lung Cancer through Upregulating Cyclin D1, Cyclin D3 and MMP7 Expression
Changqing Fang, Biying Jiang, Xiuying Shi, Chuifeng Fan
Int. J. Med. Sci. 2019; 16(3): 470-476. doi:10.7150/ijms.28139
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Glucocorticoid Regulates NLRP3 in Acute-On-Chronic Hepatitis B Liver Failure
Qian Zhao, Chen-Si Wu, Yu Fang, Yu Qian, He Wang, Yu-Chen Fan, Kai Wang
Int. J. Med. Sci. 2019; 16(3): 461-469. doi:10.7150/ijms.30424
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations
Mardiaty Iryani Abdullah, Sarni Mat Junit, Khoon Leong Ng, Jaime Jacqueline Jayapalan, Barani Karikalan, Onn Haji Hashim
Int. J. Med. Sci. 2019; 16(3): 450-460. doi:10.7150/ijms.29935
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Decreased Ambient Oxygen Tension Alters the Expression of Endothelin-1, iNOS and cGMP in Rat Alveolar Macrophages
I-Chen Chen, Yu-Tsai Lin, Jhy-Shrian Huang, Bin-Nan Wu, Jong-Hau Hsu, Mian-Shin Tan, Zen-Kong Dai
Int. J. Med. Sci. 2019; 16(3): 443-449. doi:10.7150/ijms.28353
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Histone Deacetylases (HDACs) Guided Novel Therapies for T-cell lymphomas
Qing Zhang, Shaobin Wang, Junhui Chen, Zhendong Yu
Int. J. Med. Sci. 2019; 16(3): 424-442. doi:10.7150/ijms.30154
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression
Motona Kumagai, Xin Guo, Ke-Yong Wang, Hiroto Izumi, Manabu Tsukamoto, Tamiji Nakashima, Takashi Tasaki, Nozomu Kurose, Hidetaka Uramoto, Yasuyuki Sasaguri, Kimitoshi Kohno, Sohsuke Yamada
Int. J. Med. Sci. 2019; 16(3): 416-423. doi:10.7150/ijms.26997
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Establishment of metastatic liver carcinoma model by implanting AX7 cells into rabbit liver, and its histological findings
Sun Hyun Kim, Hyung Hwan Moon, Myunghee Yoon
Int. J. Med. Sci. 2019; 16(3): 409-415. doi:10.7150/ijms.28998
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Prognostic significance of serum soluble DR5 levels in small-cell lung cancer
Zhenfa Wan, Xiaoshan Zhang, Xinshuang Yu, Yong Hou
Int. J. Med. Sci. 2019; 16(3): 403-408. doi:10.7150/ijms.28814
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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