International Journal of Medical Sciences

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10 December 2018

ISSN 1449-1907 News feeds of published articles

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International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)


Journal of Biomedicine


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Impact factor is 2.284 according to 2018 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
No Evidence for Lower Levels of Serum Vitamin D in the Presence of Hepatic Steatosis. A Study on the Portuguese General Population
Jorge Leitão, Sofia Carvalhana, Ana Paula Silva, Francisco Velasco, Isabel Medeiros, Ana Catarina Alves, Mafalda Bourbon, Bárbara Oliveiros, Armando Carvalho, Helena Cortez-Pinto
Int. J. Med. Sci. 2018; 15(14): 1778-1786. doi:10.7150/ijms.26586
[Abstract] [Full text] [PDF]

Research Paper
Development of a Model for the Prediction of Treatment Response of Uterine Leiomyomas after Uterine Artery Embolization
Youn-Jee Chung, So-Yeon Kang, Ho Jong Chun, Sung Eun Rha, Hyun Hee Cho, Jang Heub Kim, Mee-Ran Kim
Int. J. Med. Sci. 2018; 15(14): 1771-1777. doi:10.7150/ijms.28687
[Abstract] [Full text] [PDF]

Research Paper
Effectiveness of Eccentric Exercise and a Vibration or Cryotherapy Program in Enhancing Rectus Abdominis Muscle Thickness and Inter-Rectus Distance in Patients with Chronic Mid-Portion Achilles Tendinopathy: A Randomized Clinical Trial
Carlos Romero-Morales, Pedro Javier Martín-Llantino, César Calvo-Lobo, Hector Beltran-Alacreu, Daniel López-López, Rubén Sánchez-Gómez, David Rodríguez-Sanz
Int. J. Med. Sci. 2018; 15(14): 1764-1770. doi:10.7150/ijms.28656
[Abstract] [Full text] [PDF]

Research Paper
An Increased Neutrophil-to-Lymphocyte Ratio Predicts Incomplete Response to Therapy in Differentiated Thyroid Cancer
Fang Lee, Po-Sheng Yang, Ming-Nan Chien, Jie-Jen Lee, Ching-Hsiang Leung, Shih-Ping Cheng
Int. J. Med. Sci. 2018; 15(14): 1757-1763. doi:10.7150/ijms.28498
[Abstract] [Full text] [PDF]

Research Paper
The Prognostic Value of Cytokeratin and Sal-Like Protein 4 Expression in Hepatocellular Carcinoma and Intra-Hepatic Cholangiocarcinoma in Taiwan
Yih-Shyong Lai, Chiung-Chi Cheng, Ming-Tsung Lee, Wei-Ting Chao, Yen-Chang Clark Lai, Yung-Hsiang Hsu, Yi-Hsiang Liu
Int. J. Med. Sci. 2018; 15(14): 1746-1756. doi:10.7150/ijms.28440
[Abstract] [Full text] [PDF]

Pathophysiologic Implications of Cytokines Secretion during Liver Transplantation Surgery
Wonjung Hwang, Jaemin Lee
Int. J. Med. Sci. 2018; 15(14): 1737-1745. doi:10.7150/ijms.28382
[Abstract] [Full text] [PDF]

Research Paper
Effect of HMGB1 Polymorphisms on Urothelial Cell Carcinoma Susceptibility and Clinicopathological Characteristics
Sheng-Chun Hung, Shian-Shiang Wang, Jian-Ri Li, Chuan-Shu Chen, Chun-Kuang Yang, Kun-Yuan Chiu, Chen-Li Cheng, Yen-Chuan Ou, Hao-Chung Ho, Shun-Fa Yang
Int. J. Med. Sci. 2018; 15(14): 1731-1736. doi:10.7150/ijms.27901
[Abstract] [Full text] [PDF]

Research Paper
Significance of PD-L1 Expression in Tongue Cancer Development
Saori Yoshida, Hitoshi Nagatsuka, Keisuke Nakano, Yasunao Kogashiwa, Yasuhiro Ebihara, Mitsutake Yano, Masanori Yasuda
Int. J. Med. Sci. 2018; 15(14): 1723-1730. doi:10.7150/ijms.27860
[Abstract] [Full text] [PDF]

Research Paper
Elevated Tumor Necrosis Factor-a-induced Protein 8-like 2 mRNA from Peripheral Blood Mononuclear Cells in Patients with Acute Ischemic Stroke
Yuan-Yuan Zhang, Na-Na Huang, Yan-Xin Zhao, Yan-Shuang Li, Dong Wang, Yu-Chen Fan, Xiao-Hong Li
Int. J. Med. Sci. 2018; 15(14): 1713-1722. doi:10.7150/ijms.27817
[Abstract] [Full text] [PDF]

Research Paper
Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment
Ying Wang, Xiao Song, Yutian Zheng, Zeyu Liu, Yan Li, Xiaoping Qian, Xuewen Pang, Yu Zhang, Yanhui Yin
Int. J. Med. Sci. 2018; 15(14): 1702-1712. doi:10.7150/ijms.27643
[Abstract] [Full text] [PDF]

Research Paper
Circulating microRNA Panel as a Novel Biomarker to Diagnose Bisphosphonate-Related Osteonecrosis of the Jaw
Rui Yang, Yurong Tao, Chao Wang, Yi Shuai, Lei Jin
Int. J. Med. Sci. 2018; 15(14): 1694-1701. doi:10.7150/ijms.27593
[Abstract] [Full text] [PDF]

Research Paper
Bleeding Risk of Warfarin and Direct Oral Anticoagulants in Younger Population: A Historical Cohort Study Using a Japanese Claims Database
Satoshi Yokoyama, Yuki Tanaka, Kazuki Nakagita, Kouichi Hosomi, Mitsutaka Takada
Int. J. Med. Sci. 2018; 15(14): 1686-1693. doi:10.7150/ijms.28877
[Abstract] [Full text] [PDF]

Research Paper
Elevated mRNA Levels of AURKA, CDC20 and TPX2 are associated with poor prognosis of smoking related lung adenocarcinoma using bioinformatics analysis
Meng-Yu Zhang, Xiao-Xia Liu, Hao Li, Rui Li, Xiao Liu, Yi-Qing Qu
Int. J. Med. Sci. 2018; 15(14): 1676-1685. doi:10.7150/ijms.28728
[Abstract] [Full text] [PDF]

Research Paper
Infrequent Feeding of Restricted Amounts of Food Induces Stress and Adipose Tissue Inflammation, Contributing to Impaired Glucose Metabolism
Young-Sun Lee, Changmi Lee, Hee-Sook Jun
Int. J. Med. Sci. 2018; 15(14): 1667-1675. doi:10.7150/ijms.28503
[Abstract] [Full text] [PDF]

Research Paper
RKIP-Mediated NF-κB Signaling is involved in ELF-MF-mediated improvement in AD rat
Hongyan Zuo, Xiao Liu, Dewen Wang, Yang Li, Xinping Xu, Ruiyun Peng, Tao Song
Int. J. Med. Sci. 2018; 15(14): 1658-1666. doi:10.7150/ijms.28411
[Abstract] [Full text] [PDF]

Research Paper
RIPK1 Inhibition Enhances Pirarubicin Cytotoxic Efficacy through AKT-P21-dependent Pathway in Hepatocellular Carcinoma
Hechen Huang, Tianchi Chen, Yuan Zhou, Lei Geng, Tian Shen, Lin Zhou, Shusen Zheng
Int. J. Med. Sci. 2018; 15(14): 1648-1657. doi:10.7150/ijms.28289
[Abstract] [Full text] [PDF]

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