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International Journal of Biological Sciences
Journal of Cancer
Theranostics
Journal of Genomics
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 Official impact factor is 2.244 according to the latest Journal Citation Report from Thomson Reuters. - Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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Top cited papers:
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| The number of cancer survivors in the U.S. has increased from 3 million in 1971, when the National Cancer Act was enacted, to over 12 million today. Over 70% of children affected by cancer survive more than 10 years, and most are cured. Most cancer survivors are adults, with two-thirds of them 65 years of age or older and two-thirds alive at five years. The most common cancer diagnoses among survivors include breast, prostate and colorectal cancers. This review was conducted to better appreciate the challenges associated with cancer survivors and the opportunities healthcare providers have in making a difference for these patients.....details |
| In vitro, nitric oxide (NO) has been shown to have antimicrobial activity against a wide range of viruses, including influenza A virus. Therefore, we hypothesized that inhaled nitric oxide (iNO) would increase survival in vivo by reducing the viral load in C57Bl/6 mice infected with a lethal dose of influenza A/WSN/33 (H1N1; WSN/33) virus. NO was delivered to influenza-infected mice either continuously or intermittently at 80 or 160 ppm, respectively, using both prophylactic and post-infection treatment strategies. Murine survival and weight loss were assessed, and lung viral load was quantified via plaque assay. Here, we report that iNO administered prophylactically or post-influenza infection failed to improve survival of infected mice. ....details |
| The number of genetic association studies is increasing exponentially. Nonetheless, genetic association reports are prone to potential biases which may influence the reported outcome.
We hypothesized that positive outcome for a determined polymorphism might be over-reported across genetic association studies analysing a small number of polymorphisms, when compared to studies analysing the same polymorphism together with a high number of other polymorphisms.We systematically reviewed published reports on the association of glutathione s-transferase (GST) single-nucleotide polymorphisms (SNPs) and cancer outcome....details |
| Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per treatment group. Resting metabolic rates (RMR), blood pressure, heart rates and a self-reported rating scale were determined at baseline and 75 min after oral ingestion of the test products in V-8 juice. ...details |
| Adverse event reports (AERs) submitted to the US Food and Drug Administration (FDA) were reviewed to confirm platinum agent-associated adverse events, and to clarify the rank-order of these drugs in terms of susceptibility.
After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving cisplatin (CDDP), carboplatin (CBDCA), or oxaliplatin (L-OHP) were analyzed. Authorized pharmacovigilance tools were used for the quantitative detection of signals, i.e., drug-associated adverse events, including the proportional reporting ratio, the reporting odds ratio, the information component given by a Bayesian confidence propagation neural network, and the empirical Bayes geometric mean. ...details |
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Overexpression of Integrin-linked Kinase Promotes Lung Cancer Cell Migration and Invasion via NF-κB-mediated Upregulation of Matrix Metalloproteinase-9
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A Comprehensive Study Indicates PRSS1 Gene Is Significantly Associated with Pancreatitis
Jie Liu, Hong-xin Zhang
Int. J. Med. Sci. 2013; 10(8): 981-987. doi:10.7150/ijms.6164
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Combination with Anthropometric Measurements and MQSGA to Assess Nutritional Status in Chinese Hemodialysis Population
Jie Chen, Hongquan Peng, Zhimin Yuan, Kun Zhang, Long Xiao, Jialian Huang, Jingfeng Wang, Hui Huang
Int. J. Med. Sci. 2013; 10(8): 974-980. doi:10.7150/ijms.5811
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Pneumothorax as an Adverse Drug Event: An Exploratory Aggregate Analysis of the US FDA AERS Database Including A Confounding By Indication Analysis Inspired by Cornfield's Condition
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Inhibition of HCV 5′-NTR and Core Expression by a Small Hairpin RNA Delivered by a Histone Gene Carrier, HPhA
Yanhua Ding, Hong Zhang, Yuxiang Li, Di Wu, Shumei He, Yang Wang, Yuanyuan Li, Feng Wang, Junqi Niu
Int. J. Med. Sci. 2013; 10(8): 957-964. doi:10.7150/ijms.5632
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Down-Regulated CK8 Expression in Human Intervertebral Disc Degeneration
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C-Reactive Protein and Serum Amyloid A Overexpression in Lung Tissues of Chronic Obstructive Pulmonary Disease Patients: A Case-Control Study
Jose Luis López-Campos, Carmen Calero, Belén Rojano, Marta López-Porras, Javier Sáenz-Coronilla, Ana I Blanco, Verónica Sánchez-López, Daniela Tobar, Ana Montes-Worboys, Elena Arellano
Int. J. Med. Sci. 2013; 10(8): 938-947. doi:10.7150/ijms.6152
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Influence of CYP2D6 Polymorphisms on Serum Levels of Tamoxifen Metabolites in Spanish Women with Breast Cancer
Mercedes Zafra-Ceres, Tomas de Haro, Esther Farez-Vidal, Isabel Blancas, Fernando Bandres, Eduardo Martinez de Dueñas, Enrique Ochoa-Aranda, Jose A. Gomez-Capilla, Carolina Gomez-Llorente
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Lyme Borreliosis in Human Patients in Florida and Georgia, USA
Kerry L. Clark, Brian Leydet, Shirley Hartman
Int. J. Med. Sci. 2013; 10(7): 915-931. doi:10.7150/ijms.6273
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Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
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Procalcitonin-Guided Antibiotic Use in Acute Exacerbations of Idiopathic Pulmonary Fibrosis
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