International Journal of Medical Sciences

20 May 2012

ISSN 1449-1907

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International Journal of Biological Sciences

Journal of Cancer

Theranostics

Journal of Genomics

Editor-in-Chief: Dennis D. Taub, Ph.D.
Editor-in-Chief's Profile

Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
Full texts of articles appear in PubMed Central, UK PMC, and PMC Canada.
Rapid review and publication.
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(For NIH-funded researchers) Save time by submitting your paper to us - this Journal is in full compliance with NIH Public Access Requirement.
This Journal is ranked very well according to SCImago in the area of Medicine ...details

The 30th World Congress of Biomedical Laboratory Science is due to take place in Berlin, Germany from 18-22 August 2012.

Top cited papers:

DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 53
Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 99
Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 93
SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 167

The number of cancer survivors in the U.S. has increased from 3 million in 1971, when the National Cancer Act was enacted, to over 12 million today. Over 70% of children affected by cancer survive more than 10 years, and most are cured. Most cancer survivors are adults, with two-thirds of them 65 years of age or older and two-thirds alive at five years. The most common cancer diagnoses among survivors include breast, prostate and colorectal cancers. This review was conducted to better appreciate the challenges associated with cancer survivors and the opportunities healthcare providers have in making a difference for these patients.....details

In vitro, nitric oxide (NO) has been shown to have antimicrobial activity against a wide range of viruses, including influenza A virus. Therefore, we hypothesized that inhaled nitric oxide (iNO) would increase survival in vivo by reducing the viral load in C57Bl/6 mice infected with a lethal dose of influenza A/WSN/33 (H1N1; WSN/33) virus. NO was delivered to influenza-infected mice either continuously or intermittently at 80 or 160 ppm, respectively, using both prophylactic and post-infection treatment strategies. Murine survival and weight loss were assessed, and lung viral load was quantified via plaque assay. Here, we report that iNO administered prophylactically or post-influenza infection failed to improve survival of infected mice. ....details

The number of genetic association studies is increasing exponentially. Nonetheless, genetic association reports are prone to potential biases which may influence the reported outcome. We hypothesized that positive outcome for a determined polymorphism might be over-reported across genetic association studies analysing a small number of polymorphisms, when compared to studies analysing the same polymorphism together with a high number of other polymorphisms.We systematically reviewed published reports on the association of glutathione s-transferase (GST) single-nucleotide polymorphisms (SNPs) and cancer outcome....details

Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per treatment group. Resting metabolic rates (RMR), blood pressure, heart rates and a self-reported rating scale were determined at baseline and 75 min after oral ingestion of the test products in V-8 juice. ...details

Adverse event reports (AERs) submitted to the US Food and Drug Administration (FDA) were reviewed to confirm platinum agent-associated adverse events, and to clarify the rank-order of these drugs in terms of susceptibility. After a revision of arbitrary drug names and the deletion of duplicated submissions, AERs involving cisplatin (CDDP), carboplatin (CBDCA), or oxaliplatin (L-OHP) were analyzed. Authorized pharmacovigilance tools were used for the quantitative detection of signals, i.e., drug-associated adverse events, including the proportional reporting ratio, the reporting odds ratio, the information component given by a Bayesian confidence propagation neural network, and the empirical Bayes geometric mean. ...details

International Journal of Medical Sciences Cover Page

Research Paper
Relationship between Oral Anaerobic Bacteria and Otitis Media with Effusion
Nursen Topcuoglu, Fahriye Keskin, Sevgi Ciftci, Ceki Paltura, Mehmet Kulekci, Duran Ustek, Guven Kulekci
Int. J. Med. Sci. 2012; 9(3): 256-261. doi:10.7150/ijms.4382
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Donepezil Combined with Natural Hirudin Improves the Clinical Symptoms of Patients with Mild-to-Moderate Alzheimer's Disease: A 20-Week Open-Label Pilot Study
De-qiang Li, Yu-ping Zhou, Han Yang
Int. J. Med. Sci. 2012; 9(3): 248-255. doi:10.7150/ijms.4363
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Laparoscopic Management of Perforated Meckel's Diverticulum in Adults
Yinlu Ding, Yong Zhou, Zhipeng Ji, Jianliang Zhang, Qisan Wang
Int. J. Med. Sci. 2012; 9(3): 243-247. doi:10.7150/ijms.4170
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
COX-2 Expression and Tumor Angiogenesis in Thyroid Carcinoma Patients among Northeast Chinese Population-Result of a Single-Center Study
Bai Ji, Yahui Liu, Ping Zhang, Yingchao Wang, Guangyi Wang
Int. J. Med. Sci. 2012; 9(3): 237-242. doi:10.7150/ijms.4173
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Assessment of Resident Physicians in Professionalism, Interpersonal and Communication Skills: a Multisource Feedback
Bo Qu, Yu-hong Zhao, Bao-zhi Sun
Int. J. Med. Sci. 2012; 9(3): 228-236. doi:10.7150/ijms.3353
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Case Report
Hem-o-lok Clip Found in Common Bile Duct after Laparoscopic Cholecystectomy and Common Bile Duct Exploration: A Clinical Analysis Of 8 Cases
Yahui Liu, Bai Ji, Yingchao Wang, Guangyi Wang
Int. J. Med. Sci. 2012; 9(3): 225-227. doi:10.7150/ijms.4023
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Effects of STAT3 Gene Silencing and Rapamycin on Apoptosis in Hepatocarcinoma Cells
Yi Zhang, Jun-Wei Zhang, Guo-Yue Lv, Shu-Li Xie, Guang-Yi Wang
Int. J. Med. Sci. 2012; 9(3): 216-224. doi:10.7150/ijms.4004
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Case Report
Strangulated Intestinal Obstruction Secondary to a Typical Obturator Hernia: A Case Report with Literature Review
Xiaoyan Cai, Xiangyang Song, Xiujun Cai
Int. J. Med. Sci. 2012; 9(3): 213-215. doi:10.7150/ijms.3894
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Congenital Bronchial Atresia: Diagnosis and Treatment
Yuqi Wang, Weimin Dai, Yu'e Sun, Xiangyang Chu, Bo Yang, Ming Zhao
Int. J. Med. Sci. 2012; 9(3): 207-212. doi:10.7150/ijms.3690
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Case Report
Isolated Biliary Cryptococcosis Manifesting as Obstructive Jaundice in an Immunocompetent Adult
Xiujun Cai, Kun Liu, Yuelong Liang, Hong Yu, Fangfang Lv, Xiao Liang
Int. J. Med. Sci. 2012; 9(3): 200-206. doi:10.7150/ijms.3810
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review
Cancer and Radiation Therapy: Current Advances and Future Directions
Rajamanickam Baskar, Kuo Ann Lee, Richard Yeo, Kheng-Wei Yeoh
Int. J. Med. Sci. 2012; 9(3): 193-199. doi:10.7150/ijms.3635
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Effect of Bone Morphogenetic Protein-2 on Proliferation and Apoptosis of Gastric Cancer Cells
Junjie Zhang, Yanli Ge, Longe Sun, Jianchun Cao, Qiong Wu, Likun Guo, Zhirong Wang
Int. J. Med. Sci. 2012; 9(2): 184-192. doi:10.7150/ijms.3859
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Effects of a Sliding Plate on Morphology of the Epiphyseal Plate in Goat Distal Femur
Da-sheng LIN, Ke-jian LIAN, Jia-yuan HONG, Zhen-qi DING, Wen-liang ZHAI
Int. J. Med. Sci. 2012; 9(2): 178-183. doi:10.7150/ijms.3610
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Case Report
Abdominal Multiple Splenosis Mimicking Liver and Colon Tumors: A Case Report and Review of the Literature
Yahui Liu, Bai Ji, Guangyi Wang, Yingchao Wang
Int. J. Med. Sci. 2012; 9(2): 174-177. doi:10.7150/ijms.3983
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review
Cancer Survivors in the United States: A Review of the Literature and a Call to Action
Manuel Valdivieso, Ann M. Kujawa, Tisha Jones, Laurence H. Baker
Int. J. Med. Sci. 2012; 9(2): 163-173. doi:10.7150/ijms.3827
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Inhaled Nitric Oxide Therapy Fails to Improve Outcome in Experimental Severe Influenza
Ilyse Darwish, Chris Miller, Kevin C. Kain, W. Conrad Liles
Int. J. Med. Sci. 2012; 9(2): 157-162. doi:10.7150/ijms.3880
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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