International Journal of Medical Sciences

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14 November 2018

ISSN 1449-1907 News feeds of published articles

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International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)


Journal of Biomedicine


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Impact factor is 2.284 according to 2018 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Elevated mRNA Levels of AURKA, CDC20 and TPX2 are associated with poor prognosis of smoking related lung adenocarcinoma using bioinformatics analysis
Meng-Yu Zhang, Xiao-Xia Liu, Hao Li, Rui Li, Xiao Liu, Yi-Qing Qu
Int. J. Med. Sci. 2018; 15(14): 1676-1685. doi:10.7150/ijms.28728
[Abstract] [Full text] [PDF]

Research Paper
Infrequent Feeding of Restricted Amounts of Food Induces Stress and Adipose Tissue Inflammation, Contributing to Impaired Glucose Metabolism
Young-Sun Lee, Changmi Lee, Hee-Sook Jun
Int. J. Med. Sci. 2018; 15(14): 1667-1675. doi:10.7150/ijms.28503
[Abstract] [Full text] [PDF]

Research Paper
RKIP-Mediated NF-κB Signaling is involved in ELF-MF-mediated improvement in AD rat
Hongyan Zuo, Xiao Liu, Dewen Wang, Yang Li, Xinping Xu, Ruiyun Peng, Tao Song
Int. J. Med. Sci. 2018; 15(14): 1658-1666. doi:10.7150/ijms.28411
[Abstract] [Full text] [PDF]

Research Paper
RIPK1 Inhibition Enhances Pirarubicin Cytotoxic Efficacy through AKT-P21-dependent Pathway in Hepatocellular Carcinoma
Hechen Huang, Tianchi Chen, Yuan Zhou, Lei Geng, Tian Shen, Lin Zhou, Shusen Zheng
Int. J. Med. Sci. 2018; 15(14): 1648-1657. doi:10.7150/ijms.28289
[Abstract] [Full text] [PDF]

Research Paper
The effect of the primary tumor location on the survival of colorectal cancer patients after radical surgery
Xiaona Cai, Dianna Gu, Mengfeng Chen, Linger Liu, Didi Chen, Lihuai Lu, Mengdan Gao, Xuxue Ye, Xiance Jin, Congying Xie
Int. J. Med. Sci. 2018; 15(14): 1640-1647. doi:10.7150/ijms.27834
[Abstract] [Full text] [PDF]

Research Paper
Melatonin and Vitamin D Orchestrate Adipose Derived Stem Cell Fate by Modulating Epigenetic Regulatory Genes
Sara Santaniello, Sara Cruciani, Valentina Basoli, Francesca Balzano, Emanuela Bellu, Giuseppe Garroni, Giorgio Carlo Ginesu, Maria Laura Cossu, Federica Facchin, Alessandro Palmerio Delitala, Carlo Ventura, Margherita Maioli
Int. J. Med. Sci. 2018; 15(14): 1631-1639. doi:10.7150/ijms.27669
[Abstract] [Full text] [PDF]

Research Paper
Decreases in Paraoxonase-1 Activities Promote a Pro-inflammatory Effect of Lipids Peroxidation Products in Non-smoking and Smoking Patients with Acute Pancreatitis
Grzegorz Marek, Milena Ściskalska, Zygmunt Grzebieniak, Halina Milnerowicz
Int. J. Med. Sci. 2018; 15(14): 1619-1630. doi:10.7150/ijms.27647
[Abstract] [Full text] [PDF]

About stem cell research in dentistry: many doubts and too many pitfalls still affect the regenerative dentistry
Marco Tatullo
Int. J. Med. Sci. 2018; 15(14): 1616-1618. doi:10.7150/ijms.27908
[Abstract] [Full text] [PDF]

Research Paper
Enhanced basal tension in isolated rat tracheal smooth muscle stimulated by electric field stimulation under low temperature
Hsing-Won Wang, Pin-Zhir Chao, Fei-Peng Lee
Int. J. Med. Sci. 2018; 15(14): 1611-1615. doi:10.7150/ijms.27603
[Abstract] [Full text] [PDF]

Current status of endovascular treatment for dural arteriovenous fistula of the transverse-sigmoid sinus: A literature review
Kan Xu, Xue Yang, Chao Li, Jinlu Yu
Int. J. Med. Sci. 2018; 15(14): 1600-1610. doi:10.7150/ijms.27683
[Abstract] [Full text] [PDF]

Phenotypic Alteration of Hepatocytes in Non-Alcoholic Fatty Liver Disease
Hari Vishal Lakhani, Dana Sharma, Michael W. Dodrill, Athar Nawab, Nitin Sharma, Cameron Lee Cottrill, Joseph I. Shapiro, Komal Sodhi
Int. J. Med. Sci. 2018; 15(14): 1591-1599. doi:10.7150/ijms.27953
[Abstract] [Full text] [PDF]

Research Paper
Effects of the Geometrical Structure of a Honeycomb TCP on Relationship between Bone / Cartilage Formation and Angiogenesis
Hiroyuki Matsuda, Kiyofumi Takabatake, Hidetsugu Tsujigiwa, Satoko Watanabe, Satoshi Ito, Hotaka Kawai, Mei Hamada, Saori Yoshida, Keisuke Nakano, Hitoshi Nagatsuka
Int. J. Med. Sci. 2018; 15(14): 1582-1590. doi:10.7150/ijms.28452
[Abstract] [Full text] [PDF]

Research Paper
Pin1 Is Involved in HDAC6-mediated Cancer Cell Motility
Hsiang-Hao Chuang, Ming-Shyan Huang, Pei-Hui Wang, Yu-Peng Liu, Michael Hsiao, Chih-Jen Yang
Int. J. Med. Sci. 2018; 15(13): 1573-1581. doi:10.7150/ijms.27426
[Abstract] [Full text] [PDF]

Research Paper
A SHOX2 loss-of-function mutation underlying familial atrial fibrillation
Ning Li, Zhang-Sheng Wang, Xin-Hua Wang, Ying-Jia Xu, Qi Qiao, Xiu-Mei Li, Ruo-Min Di, Xiao-Juan Guo, Ruo-Gu Li, Min Zhang, Xing-Biao Qiu, Yi-Qing Yang
Int. J. Med. Sci. 2018; 15(13): 1564-1572. doi:10.7150/ijms.27424
[Abstract] [Full text] [PDF]

The Pivotal Role of Thymus in Atherosclerosis Mediated by Immune and Inflammatory Response
Xianliang Dai, Danfeng Zhang, Chaoqun Wang, Zonggui Wu, Chun Liang
Int. J. Med. Sci. 2018; 15(13): 1555-1563. doi:10.7150/ijms.27238
[Abstract] [Full text] [PDF]

Research Paper
Microarray Analysis of Differentially-expressed MicroRNAs in Acquired Middle Ear Cholesteatoma
Shumin Xie, Xiaoyu Liu, Zhen Pan, Xing Chen, Anquan Peng, Tuanfang Yin, Jihao Ren, Wei Liu
Int. J. Med. Sci. 2018; 15(13): 1547-1554. doi:10.7150/ijms.26329
[Abstract] [Full text] [PDF]

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