International Journal of Medical Sciences

Impact factor
2.284

19 February 2019

ISSN 1449-1907

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Theranostics

Journal of Cancer

International Journal of Biological Sciences

Journal of Genomics

Nanotheranostics

Journal of Bone and Joint Infection (JBJI)

Oncomedicine

Journal of Biomedicine

Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded ....
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This Journal is ranked very well according to SCImago in the area of Medicine ...details

Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Laxmaiah Manchikanti et al. Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-Up. Cited by 95
DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 79
Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 146
Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 137
SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 283

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

...details

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of these polysaccharide-rich extracts in LoVo and HT-29 human colon cancer cells. The in vitro effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Moreover, the effect on anchorage independent-cell growth was also determined. Our results showed that TV and GF extracts did inhibit human colon cell proliferation and induce cytotoxicity.. ...details

A number of biomaterials have been developed, some of which already enjoy widespread clinic use. We have devised a new honeycomb tricalcium phosphate (TCP) containing through-and-through holes of various diameters to control cartilage and bone formation. However, the way in which the geometric structure of the honeycomb TCP controls cartilage and bone tissue formation separately remains unknown. In addition, an association has been reported between bone formation and angiogenesis. Therefore, in the present study, we investigated the relationship between angiogenesis and various hole diameters in our honeycomb TCP over time in a rat ectopic hard tissue formation model.. ...details

Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste and smell, dental sensitivity.

The aim of this observational study was to investigate the prevalence of TMD symptoms and signs as well as oral implications in patients with Early Rheumatoid Arthritis (ERA), that is a RA diagnosed within 12 months, compared with a control group.

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Review
Histone Deacetylases (HDACs) Guided Novel Therapies for T-cell lymphomas
Qing Zhang, Shaobin Wang, Junhui Chen, Zhendong Yu
Int. J. Med. Sci. 2019; 16(3): 424-442. doi:10.7150/ijms.30154
[Abstract] [Full text] [PDF]

Research Paper
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression
Motona Kumagai, Xin Guo, Ke-Yong Wang, Hiroto Izumi, Manabu Tsukamoto, Tamiji Nakashima, Takashi Tasaki, Nozomu Kurose, Hidetaka Uramoto, Yasuyuki Sasaguri, Kimitoshi Kohno, Sohsuke Yamada
Int. J. Med. Sci. 2019; 16(3): 416-423. doi:10.7150/ijms.26997
[Abstract] [Full text] [PDF]

Research Paper
Establishment of metastatic liver carcinoma model by implanting AX7 cells into rabbit liver, and its histological findings
Sun Hyun Kim, Hyung Hwan Moon, Myunghee Yoon
Int. J. Med. Sci. 2019; 16(3): 409-415. doi:10.7150/ijms.28998
[Abstract] [Full text] [PDF]

Research Paper
Prognostic significance of serum soluble DR5 levels in small-cell lung cancer
Zhenfa Wan, Xiaoshan Zhang, Xinshuang Yu, Yong Hou
Int. J. Med. Sci. 2019; 16(3): 403-408. doi:10.7150/ijms.28814
[Abstract] [Full text] [PDF]

Research Paper
Changes and Significance of SYP and GAP-43 Expression in the Hippocampus of CIH Rats
Xiankun Zhu, Pei Wang, Haijun Liu, Jing Zhan, Jin Wang, Mi Li, Ling Zeng, Ping Xu
Int. J. Med. Sci. 2019; 16(3): 394-402. doi:10.7150/ijms.28359
[Abstract] [Full text] [PDF]

Research Paper
PM_2.5 Upregulates MicroRNA-146a-3p and Induces M1 Polarization in RAW264.7 Cells by Targeting Sirtuin1
Yijue Zhong, Jiping Liao, Yan Hu, Yunxia Wang, Chao Sun, Cheng Zhang, Guangfa Wang
Int. J. Med. Sci. 2019; 16(3): 384-393. doi:10.7150/ijms.30084
[Abstract] [Full text] [PDF]

Research Paper
Efficacy of Single-Dose Dexmedetomidine Combined with Low-Dose Remifentanil Infusion for Cough Suppression Compared to High-Dose Remifentanil Infusion: A Randomized, Controlled, Non-Inferiority Trial
Jae Hwan Kim, Sung Yeon Ham, Do-Hyeong Kim, Chul Ho Chang, Jeong Soo Lee
Int. J. Med. Sci. 2019; 16(3): 376-383. doi:10.7150/ijms.30227
[Abstract] [Full text] [PDF]

Research Paper
New Insight on Solute Carrier Family 27 Member 6 (SLC27A6) in Tumoral and Non-Tumoral Breast Cells
Meng-Chi Yen, Shih-Kai Chou, Jung-Yu Kan, Po-Lin Kuo, Ming-Feng Hou, Ya-Ling Hsu
Int. J. Med. Sci. 2019; 16(3): 366-375. doi:10.7150/ijms.29946
[Abstract] [Full text] [PDF]

Review
The Conserved Molecular Determinants of Virulence in Dengue Virus
Zuleeza Ahmad, Chit Laa Poh
Int. J. Med. Sci. 2019; 16(3): 355-365. doi:10.7150/ijms.29938
[Abstract] [Full text] [PDF]

Research Paper
Gene Expression Profiling in Ischemic Postconditioning to Alleviate Mouse Liver Ischemia/Reperfusion Injury
Pengpeng Zhang, Yingzi Ming, Ke Cheng, Ying Niu, Qifa Ye
Int. J. Med. Sci. 2019; 16(2): 343-354. doi:10.7150/ijms.29393
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Association between Anaesthetic Technique and Oncological Outcomes after Colorectal Carcinoma Liver Metastasis Resection
Hao Gao, Xiao-Yan Meng, Hong-Qian Wang, Feng-Feng Zhu, Ai-Ling Guo, Mei Zhu, Jin-Chao Song, Wei-Feng Yu
Int. J. Med. Sci. 2019; 16(2): 337-342. doi:10.7150/ijms.28016
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Correlation between genetic polymorphism of angiopoietin-2 gene and clinical aspects of rheumatoid arthritis
Chengqian Dai, Shu-Jui Kuo, Jin Zhao, Lulu Jin, Le Kang, Lihong Wang, Guohong Xu, Chih-Hsin Tang, Chen-Ming Su
Int. J. Med. Sci. 2019; 16(2): 331-336. doi:10.7150/ijms.30582
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia
Jingwen Sun, Jinjing Zhang, Yue Wang, Yan Li, Rui Zhang
Int. J. Med. Sci. 2019; 16(2): 324-330. doi:10.7150/ijms.27757
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock
Elliot Melendez, Jane E. Whitney, Jackson S. Norton, Melanie Silverman, Susanna Harju-Baker, Carmen Mikacenic, Mark M. Wurfel, W. Conrad Liles
Int. J. Med. Sci. 2019; 16(2): 318-323. doi:10.7150/ijms.27731
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Feasible Advantage of Bioactive/Bioresorbable Devices Made of Forged Composites of Hydroxyapatite Particles and Poly-L-lactide in Alveolar Bone Augmentation: A Preliminary Study
Shintaro Sukegawa, Hotaka Kawai, Keisuke Nakano, Takahiro Kanno, Kiyofumi Takabatake, Hitoshi Nagatsuka, Yoshihiko Furuki
Int. J. Med. Sci. 2019; 16(2): 311-317. doi:10.7150/ijms.27986
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper
Imbalance of erythropoiesis and iron metabolism in patients with thalassemia
Yumei Huang, Yu Lei, Rongrong Liu, Jiaodi Liu, Gaohui Yang, Zhifu Xiang, Yuzhen Liang, Yongrong Lai
Int. J. Med. Sci. 2019; 16(2): 302-310. doi:10.7150/ijms.27829
[Abstract] [Full text] [PDF] [PubMed] [PMC]

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