International Journal of Medical Sciences

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21 May 2019

ISSN 1449-1907 News feeds of published articles

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Journal of Genomics



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Impact factor is 2.284 according to 2018 release of Journal Citation Reports®.

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Top cited papers:

Plasma viral load was positively correlated with VWF adhesive activity, which was elevated in acute relative to chronic treated HIV-1 infection. ADAMTS13 antigen and activity were both positively correlated with plasma viral load, and ADAMTS13 activity was significantly higher in men with acute HIV infection than in uninfected controls, and in both acute and chronic untreated HIV infection relative to chronic treated infection.

Conclusion: These findings suggest that even in the setting of increased ADAMTS13 protease activity, VWF in HIV-1 infection is hyperadhesive, which may favor development of microvascular and arterial thromboses and thereby contribute to increased cardiovascular risk in HIV-1-infected individuals.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. In the present study, we have developed polysaccharide-rich extracts from Trametes versicolor (TV) and Grifola frondosa (GF) fruit bodies. We aim to evaluate the anticancer effects of these polysaccharide-rich extracts in LoVo and HT-29 human colon cancer cells. The in vitro effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Moreover, the effect on anchorage independent-cell growth was also determined. Our results showed that TV and GF extracts did inhibit human colon cell proliferation and induce cytotoxicity.. ...details
A number of biomaterials have been developed, some of which already enjoy widespread clinic use. We have devised a new honeycomb tricalcium phosphate (TCP) containing through-and-through holes of various diameters to control cartilage and bone formation. However, the way in which the geometric structure of the honeycomb TCP controls cartilage and bone tissue formation separately remains unknown. In addition, an association has been reported between bone formation and angiogenesis. Therefore, in the present study, we investigated the relationship between angiogenesis and various hole diameters in our honeycomb TCP over time in a rat ectopic hard tissue formation model.. ...details

Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste and smell, dental sensitivity.

The aim of this observational study was to investigate the prevalence of TMD symptoms and signs as well as oral implications in patients with Early Rheumatoid Arthritis (ERA), that is a RA diagnosed within 12 months, compared with a control group.

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Research Paper
Zoledronate induces cell cycle arrest and differentiation by upregulating p21 in mouse MC3T3-E1 preosteoblasts
Kuo-Chin Huang, Tsan-Wen Huang, Po-Yao Chuang, Tien-Yu Yang, Shun-Fu Chang
Int. J. Med. Sci. 2019; 16(5): 751-756. doi:10.7150/ijms.32612
[Abstract] [Full text] [PDF]

Research Paper
IFN-DC Loaded with Autophagosomes containing Virus Antigen is Highly Efficient in Inducing Virus-Specific Human T Cells
Jing Fan, Yinwei Wu, Mingchun Jiang, Lili Wang, Dandan Yin, Yajuan Zhang, Wei Ye, Yongxiang Yi
Int. J. Med. Sci. 2019; 16(5): 741-750. doi:10.7150/ijms.31830
[Abstract] [Full text] [PDF]

Research Paper
Protective Effects of Rosmarinic Acid against Selenite-Induced Cataract and Oxidative Damage in Rats
Chia-Fang Tsai, Jia-Ying Wu, Yu-Wen Hsu
Int. J. Med. Sci. 2019; 16(5): 729-740. doi:10.7150/ijms.32222
[Abstract] [Full text] [PDF]

Research Paper
Dynamic Differences Of Red Cell Distribution Width Levels Contribute To The Differential Diagnosis Of Hepatitis B Virus-related Chronic Liver Diseases: A Case-control Study
Mengjie Zhu, Man Han, Xiaoyu Xiao, Songsong Lu, Zhao Guan, Ying Song, Chen Liu
Int. J. Med. Sci. 2019; 16(5): 720-728. doi:10.7150/ijms.31826
[Abstract] [Full text] [PDF]

The Pharmacological Potential of Oil Palm Phenolics (OPP) Individual Components
Syed-Badrul Syarifah-Noratiqah, Mohamed S Zulfarina, Shihab Uddin Ahmad, Syed Fairus, Isa Naina-Mohamed
Int. J. Med. Sci. 2019; 16(5): 711-719. doi:10.7150/ijms.29934
[Abstract] [Full text] [PDF]

Human Trabecular Meshwork Progenitors
Qin Zhu, Yuan Zhang, Sean Tighe, Yongsong Liu, Yingting Zhu, Min Hu
Int. J. Med. Sci. 2019; 16(5): 704-710. doi:10.7150/ijms.32089
[Abstract] [Full text] [PDF]

Research Paper
Hyperglycemia inhibits osteoblastogenesis of rat bone marrow stromal cells via activation of the Notch2 signaling pathway
Kuo-Chin Huang, Po-Yao Chuang, Tien-Yu Yang, Tsan-Wen Huang, Shun-Fu Chang
Int. J. Med. Sci. 2019; 16(5): 696-703. doi:10.7150/ijms.32707
[Abstract] [Full text] [PDF]

Research Paper
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling
Yih-Farng Liou, Yih-Shou Hsieh, Tung-Wei Hung, Pei-Ni Chen, Yan-Zin Chang, Shao-Hsuan Kao, Shu-Wen Lin, Horng-Rong Chang
Int. J. Med. Sci. 2019; 16(5): 686-695. doi:10.7150/ijms.32763
[Abstract] [Full text] [PDF]

Research Paper
Exercise Preconditioning Attenuates Neurological Injury by Preserving Old and Newly Formed HSP72-Containing Neurons in Focal Brain Ischemia Rats
Yu-Lin Wang, Cheng-Hsien Lin, Chi-Chun Chen, Ching-Ping Chang, Kao-Chang Lin, Fong-Chin Su, Willy Chou
Int. J. Med. Sci. 2019; 16(5): 675-685. doi:10.7150/ijms.32962
[Abstract] [Full text] [PDF]

Research Paper
Risk Factors of Intraoperative Dysglycemia in Elderly Surgical Patients
Cornelia Knaak, Tobias Wollersheim, Rudolf Mörgeli, Claudia Spies, Gerald Vorderwülbecke, Victoria Windmann, Sophia Kuenz, Maryam Kurpanik, Gunnar Lachmann
Int. J. Med. Sci. 2019; 16(5): 665-674. doi:10.7150/ijms.32971
[Abstract] [Full text] [PDF]

Research Paper
Efficacy of Anterior Stromal Puncture Surgery with Corneal Bandage Lens for Bullous Keratopathy
Guigang Li, Jiao Zheng, Jin Gong, Alataree Sameer, Xinyu Li, Yuan Zhang, Sean Tighe, Yingting Zhu, Ping Wang
Int. J. Med. Sci. 2019; 16(5): 660-664. doi:10.7150/ijms.31669
[Abstract] [Full text] [PDF]

Research Paper
HSDL2 Promotes Bladder Cancer Growth In Vitro and In Vivo
Ling-Hua Jia, Mei-Di Hu, Yuan Liu, Xing Xiong, Wei-Jia Wang, Jin-Gen Wang, Qiu-Gen Li
Int. J. Med. Sci. 2019; 16(5): 654-659. doi:10.7150/ijms.31288
[Abstract] [Full text] [PDF]

Research Paper
Naringenin Ameliorates Renovascular Hypertensive Renal Damage by Normalizing the Balance of Renin-Angiotensin System Components in Rats
Zhizhi Wang, Shanshan Wang, Jianqiao Zhao, Changan Yu, Yi Hu, Yimin Tu, Zufang Yang, Jingang Zheng, Yong Wang, Yanxiang Gao
Int. J. Med. Sci. 2019; 16(5): 644-653. doi:10.7150/ijms.31075
[Abstract] [Full text] [PDF]

Research Paper
Eicosapentaenoic acids enhance chemosensitivity through connexin 43 upregulation in murine melanoma models
Chih-Jen Yang, Chi-Te Kuo, Li-Hsien Wu, Man-Chin Chen, Christian Ronquillo Pangilinan, Naphichaya Phacharapiyangkul, Wangta Liu, Ya-Huey Chen, Che-Hsin Lee
Int. J. Med. Sci. 2019; 16(5): 636-643. doi:10.7150/ijms.30889
[Abstract] [Full text] [PDF]

Research Paper
Clostridium difficile Infection Risk with Important Antibiotic Classes: An Analysis of the FDA Adverse Event Reporting System
Chengwen Teng, Kelly R. Reveles, Obiageri O. Obodozie-Ofoegbu, Christopher R. Frei
Int. J. Med. Sci. 2019; 16(5): 630-635. doi:10.7150/ijms.30739
[Abstract] [Full text] [PDF]

Research Paper
Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Late-stage Age-Related Macular Degeneration
Antonio Pinna, Giuliana Solinas, Ermete Giancipoli, Tiziana Porcu, Angelo Zinellu, Giuseppe D'Amico-Ricci, Francesco Boscia, Paolo Lanzetta, Teresio Avitabile, Arthur G. Schwartz, Ciriaco Carru
Int. J. Med. Sci. 2019; 16(5): 623-629. doi:10.7150/ijms.30155
[Abstract] [Full text] [PDF]

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