International Journal of Medical Sciences

Impact factor
2.284

23 October 2018

ISSN 1449-1907 News feeds of published articles

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Impact factor is 2.284 according to 2018 release of Journal Citation ReportsĀ®.

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Top cited papers:

Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details
Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic pain without disc herniation is a common cause of suffering and disability in the adult population. Once conservative management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a management tool. Despite a paucity of evidence, cervical epidural injections are one of the most commonly performed nonsurgical interventions in the management of chronic axial or disc-related neck pain....details
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Research Paper
Melatonin and Vitamin D Orchestrate Adipose Derived Stem Cell Fate by Modulating Epigenetic Regulatory Genes
Sara Santaniello, Sara Cruciani, Valentina Basoli, Francesca Balzano, Emanuela Bellu, Giuseppe Garroni, Giorgio Carlo Ginesu, Maria Laura Cossu, Federica Facchin, Alessandro Palmerio Delitala, Carlo Ventura, Margherita Maioli
Int. J. Med. Sci. 2018; 15(14): 1631-1639. doi:10.7150/ijms.27669
[Abstract] [Full text] [PDF]

Research Paper
Decreases in Paraoxonase-1 Activities Promote a Pro-inflammatory Effect of Lipids Peroxidation Products in Non-smoking and Smoking Patients with Acute Pancreatitis
Grzegorz Marek, Milena Ściskalska, Zygmunt Grzebieniak, Halina Milnerowicz
Int. J. Med. Sci. 2018; 15(14): 1619-1630. doi:10.7150/ijms.27647
[Abstract] [Full text] [PDF]

Review
About stem cell research in dentistry: many doubts and too many pitfalls still affect the regenerative dentistry
Marco Tatullo
Int. J. Med. Sci. 2018; 15(14): 1616-1618. doi:10.7150/ijms.27908
[Abstract] [Full text] [PDF]

Research Paper
Enhanced basal tension in isolated rat tracheal smooth muscle stimulated by electric field stimulation under low temperature
Hsing-Won Wang, Pin-Zhir Chao, Fei-Peng Lee
Int. J. Med. Sci. 2018; 15(14): 1611-1615. doi:10.7150/ijms.27603
[Abstract] [Full text] [PDF]

Review
Current status of endovascular treatment for dural arteriovenous fistula of the transverse-sigmoid sinus: A literature review
Kan Xu, Xue Yang, Chao Li, Jinlu Yu
Int. J. Med. Sci. 2018; 15(14): 1600-1610. doi:10.7150/ijms.27683
[Abstract] [Full text] [PDF]

Review
Phenotypic Alteration of Hepatocytes in Non-Alcoholic Fatty Liver Disease
Hari Vishal Lakhani, Dana Sharma, Michael W. Dodrill, Athar Nawab, Nitin Sharma, Cameron Lee Cottrill, Joseph I. Shapiro, Komal Sodhi
Int. J. Med. Sci. 2018; 15(14): 1591-1599. doi:10.7150/ijms.27953
[Abstract] [Full text] [PDF]

Research Paper
Effects of the Geometrical Structure of a Honeycomb TCP on Relationship between Bone / Cartilage Formation and Angiogenesis
Hiroyuki Matsuda, Kiyofumi Takabatake, Hidetsugu Tsujigiwa, Satoko Watanabe, Satoshi Ito, Hotaka Kawai, Mei Hamada, Saori Yoshida, Keisuke Nakano, Hitoshi Nagatsuka
Int. J. Med. Sci. 2018; 15(14): 1582-1590. doi:10.7150/ijms.28452
[Abstract] [Full text] [PDF]

Research Paper
Pin1 Is Involved in HDAC6-mediated Cancer Cell Motility
Hsiang-Hao Chuang, Ming-Shyan Huang, Pei-Hui Wang, Yu-Peng Liu, Michael Hsiao, Chih-Jen Yang
Int. J. Med. Sci. 2018; 15(13): 1573-1581. doi:10.7150/ijms.27426
[Abstract] [Full text] [PDF]

Research Paper
A SHOX2 loss-of-function mutation underlying familial atrial fibrillation
Ning Li, Zhang-Sheng Wang, Xin-Hua Wang, Ying-Jia Xu, Qi Qiao, Xiu-Mei Li, Ruo-Min Di, Xiao-Juan Guo, Ruo-Gu Li, Min Zhang, Xing-Biao Qiu, Yi-Qing Yang
Int. J. Med. Sci. 2018; 15(13): 1564-1572. doi:10.7150/ijms.27424
[Abstract] [Full text] [PDF]

Review
The Pivotal Role of Thymus in Atherosclerosis Mediated by Immune and Inflammatory Response
Xianliang Dai, Danfeng Zhang, Chaoqun Wang, Zonggui Wu, Chun Liang
Int. J. Med. Sci. 2018; 15(13): 1555-1563. doi:10.7150/ijms.27238
[Abstract] [Full text] [PDF]

Research Paper
Microarray Analysis of Differentially-expressed MicroRNAs in Acquired Middle Ear Cholesteatoma
Shumin Xie, Xiaoyu Liu, Zhen Pan, Xing Chen, Anquan Peng, Tuanfang Yin, Jihao Ren, Wei Liu
Int. J. Med. Sci. 2018; 15(13): 1547-1554. doi:10.7150/ijms.26329
[Abstract] [Full text] [PDF]

Research Paper
Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs
Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huang
Int. J. Med. Sci. 2018; 15(13): 1537-1546. doi:10.7150/ijms.24296
[Abstract] [Full text] [PDF]

Research Paper
Effect of mistletoe on endometrial stromal cell survival and vascular endothelial growth factor expression in patients with endometriosis
Jeong Min Moon, Youn-Jee Chung, Boah Chae, Hee Jin Kang, Hyun Hee Cho, Jang Heub Kim, Mee-Ran Kim
Int. J. Med. Sci. 2018; 15(13): 1530-1536. doi:10.7150/ijms.28470
[Abstract] [Full text] [PDF]

Research Paper
Comparisons of Pressure-controlled Ventilation with Volume Guarantee and Volume-controlled 1:1 Equal Ratio Ventilation on Oxygenation and Respiratory Mechanics during Robot-assisted Laparoscopic Radical Prostatectomy: a Randomized-controlled Trial
Min-Soo Kim, Sarah Soh, So Yeon Kim, Min sup Song, Jin Ha Park
Int. J. Med. Sci. 2018; 15(13): 1522-1529. doi:10.7150/ijms.28442
[Abstract] [Full text] [PDF]

Research Paper
Ethanol Extract from Brucea Javanica Seed Inhibits Angiogenesis Mediated by Platelet Derived Growth Factor Receptor-beta
Xiaotong Wang, Yunyun Li, Yan Mou, Zhen Yue, Haiying Zhang, Ronggui Li, Hongxia Sun
Int. J. Med. Sci. 2018; 15(13): 1517-1521. doi:10.7150/ijms.28337
[Abstract] [Full text] [PDF]

Research Paper
Simvastatin Protects Heart from Pressure Overload Injury by Inhibiting Excessive Autophagy
Feifei Su, Miaoqian Shi, Jian Zhang, Qiangsun Zheng, Dongwei Zhang, Wei Zhang, Haichang Wang, Xue Li
Int. J. Med. Sci. 2018; 15(13): 1508-1516. doi:10.7150/ijms.28106
[Abstract] [Full text] [PDF]

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