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Volume 22 (9); 2025

Research Papers

Solute Carrier Family 35 A2 (SLC35A2) Promotes Tumor Progression through MYC-Mediated Pathways in Colorectal Cancer Kuei-Yen Tsai, Po-Li Wei, Cheng-Chin Lee, Crystal Ngofi Zumbi, G. M. Shazzad Hossain Prince, Uyanga Batzorig, Chien-Yu Huang, Yu-Jia Chang Int. J. Med. Sci. 2025; 22(9): 1992-2009. doi:10.7150/ijms.109767 Full text PDF PubMed PMC

Transcription factor 7-like 2 rs77961654 polymorphism is related to stable angina and acute coronary syndrome in a Chinese population Teng-Hung Yu, Wei-Hua Tang, Thung-Lip Lee, Chin-Feng Hsuan, Chia-Chang Hsu, Chao-Ping Wang, Ching-Ting Wei, Min-Chih Cheng, Fu-Mei Chung, Yau-Jiunn Lee, I-Ting Tsai Int. J. Med. Sci. 2025; 22(9): 2020-2030. doi:10.7150/ijms.108111 Full text PDF PubMed PMC

Modulation of Chemotherapy Sensitivity of Breast Cancer Cells through Transforming Growth Factor-beta Pathway-mediated Alterations in DNA Damage Response Abdullah S. Alhamed, Mohammad S. El-Wetidy, Mervat M. Abdelwahed, Sabry M. Attia, Abdulrahman M. Alabkka, Saleh A. Alaraj, Khalid Alhazzani, Ahmed Z. Alanazi, Faris Almutairi, Ibrahem A. Alotibi, Mohammed Alqinyah Int. J. Med. Sci. 2025; 22(9): 2031-2039. doi:10.7150/ijms.111217 Full text PDF PubMed PMC

Malignant features related PRDX1 associated with osimertinib sensitivity of EGFR-mutant lung adenocarcinoma Wenying Jiang, Maonan Wang, Xiaoqian Yu, Guoqian Liu, Xiaoyun He, Cheng Mei, Chunlin Ou Int. J. Med. Sci. 2025; 22(9): 2040-2058. doi:10.7150/ijms.107255 Full text PDF PubMed PMC

Cordycepin ameliorates morphine tolerance by inhibiting spinal cord ferroptosis and inflammation via targeting SIRT1 Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Feng Gao Int. J. Med. Sci. 2025; 22(9): 2059-2074. doi:10.7150/ijms.108518 Full text PDF PubMed PMC

Emodin: an alveolar macrophage protector in acute pancreatitis induced lung injury Zhe Chen, Xuanchi Dong, Yongwei Song, Bowen Lan, Yalan Luo, Haiyun Wen, Hailong Chen Int. J. Med. Sci. 2025; 22(9): 2075-2087. doi:10.7150/ijms.105965 Full text PDF PubMed PMC

Reduced risk of diabetic retinopathy in osteoarthritis patients undergoing joint replacement surgery Chin-Te Huang, Yat-Yin Law, Kai Wang, Chia-Yi Lee, Jing-Yang Huang, Shun-Fa Yang, Hsiang-Wen Chien Int. J. Med. Sci. 2025; 22(9): 2132-2138. doi:10.7150/ijms.109689 Full text PDF PubMed PMC

Comprehensive Characterization of the Oxidative Stress Profiles in Neonatal Necrotizing Enterocolitis Xiaofeng Xiong, Luyao Wu, Xin Liu, Jing Wang, Jun Xiao, Ke Chen, Didi Zhuansun, Xinyao Meng, Jiexiong Feng, Xuyong Chen Int. J. Med. Sci. 2025; 22(9): 2139-2154. doi:10.7150/ijms.109008 Full text PDF PubMed PMC

Genetic variant rs2243115 of the IL-12/IL-35 pathway contributes to the risk of coronary artery disease Qianwen Chen, Wenjuan Zhang, Tian Xie, Jiangtao Dong, Junxia Zhang, Lingfeng Zha Int. J. Med. Sci. 2025; 22(9): 2155-2164. doi:10.7150/ijms.102562 Full text PDF PubMed PMC

Establishing a Risk Prediction Model for Nasopharyngeal Carcinoma Based on Anti-BNLF2b Serological Biomarkers: A Retrospective Study Hengrong Shao, Mengting Chen, Yufei Xiao, Li Xu, Huaquan Cao, Bo Hong, Yun Qian Int. J. Med. Sci. 2025; 22(9): 2165-2173. doi:10.7150/ijms.110758 Full text PDF PubMed PMC

Early Hyperbaric Oxygen Therapy Promotes Recovery of Blunt Liver Injury in Rats via Inhibiting Inflammatory Response and Oxidative Stress Houyu Zhao, Tingting Zhang, Yan Wang, Yiqun Fang Int. J. Med. Sci. 2025; 22(9): 2174-2185. doi:10.7150/ijms.109842 Full text PDF PubMed PMC

Analysis of the Relationship Between NF-κB1 and Cytokine Gene Expression in Hematological Malignancy: Leveraging Explained Artificial Intelligence and Machine Learning for Small Dataset Insights Jae-Seung Jeong, Hyunsu Ju, Chi-Hyun Cho Int. J. Med. Sci. 2025; 22(9): 2208-2226. doi:10.7150/ijms.109493 Full text PDF PubMed PMC

Treatable traits identified in Chinese patients hospitalized with AECOPD: A Multicenter Cohort Study Weiwei Meng, Jiankang Wu, Jiayu Wang, Rui Zhao, Sisi Liu, Naishu Xie, Qixuan Huang, Lijun Liu, Yanchao Liang, Huihui Zeng, Yiming Ma, Yan Chen Int. J. Med. Sci. 2025; 22(9): 2227-2236. doi:10.7150/ijms.111294 Full text PDF PubMed PMC

Risks of cardiovascular disease and cerebrovascular disease following kidney transplantation: A nationwide, population-based cohort study Tung-Han Tsai, Kuang-Hua Huang, Hsin Chen, Shuo-Yan Gau, Kun-Yu Su, Min-Ling Tsai, Chien-Ying Lee Int. J. Med. Sci. 2025; 22(9): 2237-2246. doi:10.7150/ijms.108744 Full text PDF PubMed PMC

Risk of Sleep Disorders among Patients with Tourette Syndrome: A Population-Based Cohort Study in Taiwan Ning-Jen Chung, Yung-Rung Lai, Yih Yang, Shuo-Yan Gau, Shiang-Wen Huang, Tung-Han Tsai, Kuang-Hua Huang, Chien-Ying Lee Int. J. Med. Sci. 2025; 22(9): 2247-2256. doi:10.7150/ijms.107983 Full text PDF PubMed PMC

Reviews

Bacterial exotoxins in medicine: potential value and perspectives Yuming Xiao, Zhou Yan, Fangyuan Ren, Yurong Tan Int. J. Med. Sci. 2025; 22(9): 2010-2019. doi:10.7150/ijms.110104 Full text PDF PubMed PMC

Application and research progress of artificial intelligence in allergic diseases Hong Tan, Xuehua Zhou, Huajie Wu, Min Wang, Han Zhou, Yue Qin, Yun Zhang, Qiuhong Li, Jianfeng Luo, Hui Su, Xin Sun Int. J. Med. Sci. 2025; 22(9): 2088-2102. doi:10.7150/ijms.105422 Full text PDF PubMed PMC

Heterogeneity of Renal Endothelial Cells, Interact with Neighboring Cells, and Endothelial Injury in Chronic Kidney Disease: Mechanisms and Therapeutic Implications Meiyu Zhang, Wu Liu, Haoran Dai, Hanxue Jiang, Qihan Zhao, Wenbin Liu, Hongliang Rui, Baoli Liu Int. J. Med. Sci. 2025; 22(9): 2103-2118. doi:10.7150/ijms.108299 Full text PDF PubMed PMC

Novel insights into the role of ferroptosis in temporomandibular joint osteoarthritis and knee osteoarthritis Yuxin Zhang, Dahe Zhang, Xiaoyu Liao, Qingyu Xu, Lingtong Bu, Jisi Zheng, Pei Shen, Chi Yang Int. J. Med. Sci. 2025; 22(9): 2119-2131. doi:10.7150/ijms.107057 Full text PDF PubMed PMC

Harnessing Oncolytic Viruses for Targeted Therapy in Triple-Negative Breast Cancer Shasha Tang, Liyun Yong, Yong Cui, Haibin Li, Evelyne Bischof, Fengfeng Cai Int. J. Med. Sci. 2025; 22(9): 2186-2207. doi:10.7150/ijms.105683 Full text PDF PubMed PMC

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