Int J Med Sci 2020; 17(9):1142-1146. doi:10.7150/ijms.45743
Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
1. Department of Infectious Diseases, Yongchuan Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.
2. Cancer center, Daping Hospital, The Third Military Medical University, Yuzhong District, Chongqing 400042, P.R. China.
3. Department of Infectious Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.
4. Chongqing Yongchuan District Center for Disease Control and Prevention, Chongqing 400016, P.R. China.
#These authors contributed equally to this work.
Wei XY, Jing D, Jia B, Li Q, Zhou XQ, Gong MF, Zou JB, Zhang Q, Huang WX, Tian WG. Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19. Int J Med Sci 2020; 17(9):1142-1146. doi:10.7150/ijms.45743. Available from http://www.medsci.org/v17p1142.htm
Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea.
Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim guidance for NCP and divided into diarrhea and non-diarrhea groups. The laboratory tests liver and kidney function, blood routine, coagulation function, and immune status.
Results: The study population included 70 hospitalized patients with confirmed CONV-2019. NCP patients (43males and 27 females) with a mean age of 48.57±17.80 (9~82) years and only 4.3% of patients have lung-related diseases. The positive rate of ESR, CRP, PT, IL6, lymphocyte count, GGT, Prealbumin and CD4 was more than 50%. We further analyzed the differences between 8 diarrhea patients and 62 non-diarrhea patients. Among these indicators, only Lymphocyte, CRP, Prealbumin and Cystatin C positive rate is more than 50%. Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased.
Conclusion: Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients.
Keywords: Peripheral blood, COVID-19, GGT, Diarrhea