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Volume 17 (9); 2020

Research Papers

Possible misdiagnosis of 46,XX testicular disorders of sex development in infertile males
Tong Chen, Linlin Tian, Xianlong Wang, Demin Fan, Gang Ma, Rong Tang, Xujun Xuan
Int. J. Med. Sci. 2020; 17(9): 1136-1141. doi:10.7150/ijms.46058
[Abstract] [Full text] [PDF]

Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
Xiao-Yu Wei, Ding Jing, Bei Jia, Qing Li, Xia-Qia Zhou, Ming-Feng Gong, Jing-Bo Zou, Qiang Zhang, Wen-Xiang Huang, Wen-Guang Tian
Int. J. Med. Sci. 2020; 17(9): 1142-1146. doi:10.7150/ijms.45743
[Abstract] [Full text] [PDF]

N-acetylcysteine Restored Heart Rate Variability and Prevented Serious Adverse Events in Transfusion-dependent Thalassemia Patients: a Double-blind Single Center Randomized Controlled Trial
Sintip Pattanakuhar, Arintaya Phrommintikul, Adisak Tantiworawit, Somdet Srichairattanakool, Siriporn C. Chattipakorn, Nipon Chattipakorn
Int. J. Med. Sci. 2020; 17(9): 1147-1155. doi:10.7150/ijms.45795
[Abstract] [Full text] [PDF]

Baicalein Neutralizes Hypercholesterolemia-Induced Aggravation of Oxidative Injury in Rats
Abdulaziz MS AlSaad, Mohamed Mohany, Mohammed S Almalki, Ibrahim Almutham, Abdulwahab A Alahmari, Mohammed AlSulaiman, Salim S Al-Rejaie
Int. J. Med. Sci. 2020; 17(9): 1156-1166. doi:10.7150/ijms.46108
[Abstract] [Full text] [PDF]

Persistent oppression and simple decompression both exacerbate spinal cord ascorbate levels
Yawen Zhang, Guojin Hou, Wenliang Ji, Feng Rao, Rubing Zhou, Shan Gao, Lanqun Mao, Fang Zhou
Int. J. Med. Sci. 2020; 17(9): 1167-1176. doi:10.7150/ijms.41289
[Abstract] [Full text] [PDF]

Circ-APBB1IP as a Prognostic Biomarker Promotes Clear Cell Renal Cell Carcinoma Progression Through The ERK1/2 Signaling Pathway
Jierong Mo, Yuwan Zhao, Zhixian Ao, Lixin Chen, Shanhong Lin, Wenfeng Zeng, Haokai Wu, Jianjun Liu
Int. J. Med. Sci. 2020; 17(9): 1177-1186. doi:10.7150/ijms.44550
[Abstract] [Full text] [PDF]

The relationships of genetic polymorphisms of the long noncoding RNA growth arrest-specific transcript 5 with uterine cervical cancer
Shun-Long Weng, Soo-Cheen Ng, Yueh‐Chun Lee, Yi-Hsuan Hsiao, Chun-Fang Hsu, Shun-Fa Yang, Po-Hui Wang
Int. J. Med. Sci. 2020; 17(9): 1187-1195. doi:10.7150/ijms.44583
[Abstract] [Full text] [PDF]

Downregulation of P300/CBP-Associated Factor Attenuates Myocardial Ischemia-Reperfusion Injury Via Inhibiting Autophagy
Liqiang Qiu, Changwu Xu, Hao Xia, Jing Chen, Huafen Liu, Hong Jiang
Int. J. Med. Sci. 2020; 17(9): 1196-1206. doi:10.7150/ijms.44604
[Abstract] [Full text] [PDF]

S1P promotes IL-6 expression in osteoblasts through the PI3K, MEK/ERK and NF-κB signaling pathways
Sung-Lin Hu, Chien-Chung Huang, Tzu-Ting Tzeng, Shan-Chi Liu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Hsin Tang
Int. J. Med. Sci. 2020; 17(9): 1207-1214. doi:10.7150/ijms.44612
[Abstract] [Full text] [PDF]

Notch1 Affects Chemo-resistance Through Regulating Epithelial-Mesenchymal Transition (EMT) in Epithelial Ovarian cancer cells
Xue-qian Qian, Sang-sang Tang, Yuan-ming Shen, Li-li Chen, Xiao-dong Cheng, Xiao-yun Wan
Int. J. Med. Sci. 2020; 17(9): 1215-1223. doi:10.7150/ijms.44683
[Abstract] [Full text] [PDF]

Long non-coding RNA LINC01503 promotes the progression of hepatocellular carcinoma via activating MAPK/ERK pathway
Mu-Ru Wang, Dan Fang, Mu-Ping Di, Jia-Lun Guan, Ge Wang, Lian Liu, Jia-Qi Sheng, De-An Tian, Pei-Yuan Li
Int. J. Med. Sci. 2020; 17(9): 1224-1234. doi:10.7150/ijms.45256
[Abstract] [Full text] [PDF]

Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis
Yong-Seok Han, Yeo Min Yoon, Gyeongyun Go, Jun Hee Lee, Sang Hun Lee
Int. J. Med. Sci. 2020; 17(9): 1235-1245. doi:10.7150/ijms.42603
[Abstract] [Full text] [PDF]

AKR1B10 Inhibitor Epalrestat Facilitates Sorafenib-Induced Apoptosis and Autophagy Via Targeting the mTOR Pathway in Hepatocellular Carcinoma
Nan Geng, Yuanyuan Jin, Yurong Li, Shixuan Zhu, Han Bai
Int. J. Med. Sci. 2020; 17(9): 1246-1256. doi:10.7150/ijms.42956
[Abstract] [Full text] [PDF]

IL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway
Lin Lu, Peipei Wang, Yonghong Zou, Zhiqiang Zha, Haowei Huang, Mingmei Guan, Yong Wu, Guolong Liu
Int. J. Med. Sci. 2020; 17(9): 1257-1268. doi:10.7150/ijms.44285
[Abstract] [Full text] [PDF]

Identification of the key genes and microRNAs in adult acute myeloid leukemia with FLT3 mutation by bioinformatics analysis
Shuyi Chen, Yimin Chen, Zhiguo Zhu, Huo Tan, Jielun Lu, Pengfei Qin, Lihua Xu
Int. J. Med. Sci. 2020; 17(9): 1269-1280. doi:10.7150/ijms.46441
[Abstract] [Full text] [PDF]

Factors associated with death outcome in patients with severe coronavirus disease-19 (COVID-19): a case-control study
Feng Pan, Lian Yang, Yuncheng Li, Bo Liang, Lin Li, Tianhe Ye, Lingli Li, Dehan Liu, Shan Gui, Yu Hu, Chuansheng Zheng
Int. J. Med. Sci. 2020; 17(9): 1281-1292. doi:10.7150/ijms.46614
[Abstract] [Full text] [PDF]

Mitochondrial Transcription Factor A added to Osteocytes in a Stressed Environment has a Cytoprotective Effect
Shusuke Ueda, Miyako Shimasaki, Toru Ichiseki, Hiroaki Hirata, Norio kawahara, Yoshimichi Ueda
Int. J. Med. Sci. 2020; 17(9): 1293-1299. doi:10.7150/ijms.45335
[Abstract] [Full text] [PDF]