Epidemiological Determinants of Successful Vaccine Development

Nishiura, Hiroshi; Mizumoto, Kenji

doi:10.7150/ijms.5689

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Int J Med Sci 2013; 10(4):382-384. doi:10.7150/ijms.5689 This issue Cite

Short Research Communication

Epidemiological Determinants of Successful Vaccine Development

Hiroshi Nishiura^1,2✉, Kenji Mizumoto^1,3

1. School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong SAR, China.
2. PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama, 332-0012 Japan.
3. Department of International Health, Nagasaki University Institute of Tropical Medicine and GCOE, 1-12-4 Sakamoto, Nagasaki, 852-8523 Japan.

Citation:

Nishiura H, Mizumoto K. Epidemiological Determinants of Successful Vaccine Development. Int J Med Sci 2013; 10(4):382-384. doi:10.7150/ijms.5689. https://www.medsci.org/v10p0382.htm

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Abstract

Epidemiological determinants of successful vaccine development were explored using measurable biological variables including antigenic stability and requirement of T-cell immunity. Employing a logistic regression model, we demonstrate that a high affinity with blood and immune cells and pathogen interactions (e.g. interference) would be the risk factors of failure for vaccine development.

Keywords: Vaccination, epidemiology, infectious disease, immunization, statistical model.

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APA

Nishiura, H., Mizumoto, K. (2013). Epidemiological Determinants of Successful Vaccine Development. International Journal of Medical Sciences, 10(4), 382-384. https://doi.org/10.7150/ijms.5689.

ACS

Nishiura, H.; Mizumoto, K. Epidemiological Determinants of Successful Vaccine Development. Int. J. Med. Sci. 2013, 10 (4), 382-384. DOI: 10.7150/ijms.5689.

NLM

Nishiura H, Mizumoto K. Epidemiological Determinants of Successful Vaccine Development. Int J Med Sci 2013; 10(4):382-384. doi:10.7150/ijms.5689. https://www.medsci.org/v10p0382.htm

CSE

Nishiura H, Mizumoto K. 2013. Epidemiological Determinants of Successful Vaccine Development. Int J Med Sci. 10(4):382-384.

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