International Journal of Medical Sciences

Impact factor
2.399

20 October 2017

ISSN 1449-1907 News feeds of published articles

My Manuscript | My Account

Journal of Genomics now in PubMed/PubMed Central. Submit manuscript...

Journal of Biomedicinenew

Theranostics

Journal of Cancer

Oncomedicine

International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Nanotheranostics

PubMed Central Indexed in Journal Impact Factor

Int J Med Sci 2016; 13(6):445-450. doi:10.7150/ijms.14256

Research Paper

Longitudinal Associations between Triglycerides and Metabolic Syndrome Components in a Beijing Adult Population, 2007-2012

Li-Xin Tao1,2, Kun Yang 1,2, Xiang-Tong Liu1,2, Kai Cao1,2, Hui-Ping Zhu1,2, Yan-Xia Luo1,2, Jin Guo1,2, Li-Juan Wu1,2, Xia Li1,2,3✉, Xiu-Hua Guo1,2✉

1. School of Public Health, Capital Medical University, Beijing 100069, China
2. Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing 100069, China
3. Department of Epidemiology & Public Health, University College Cork, Cork 78746, Ireland

Abstract

Background: Longitudinal associations between triglycerides (TG) and other metabolic syndrome (MetS) components have rarely been reported. The purpose was to investigate the longitudinal association between TG and other MetS components with time.

Methods: The longitudinal study was established in 2007 on individuals who attended health check-ups at Beijing Tongren Hospital and Beijing Xiaotangshan Hospital. Data used in this study was based on 7489 participants who had at least three health check-ups over a period of 5-year follow up. Joint model was used to explore longitudinal associations between TG and other MetS components after adjusted for age.

Results: There were positive correlations between TG and other MetS components except for high density lipoprotein (HDL), and the correlations increased with time. A negative correlation was displayed between TG and HDL, and the correlation also increased with time. Among all five pairs of TG and other MetS components, the marginal correlation between TG and body mass index (BMI) was the largest for both men and women. The marginal correlation between TG and fasting plasma glucose was the smallest for men, while the marginal correlation between TG and diastolic blood pressure was the smallest for women.

Conclusions: The longitudinal association between TG and other MetS components increased with time. Among five pairs of TG and other MetS components, the longitudinal correlation between TG and BMI was the largest. It is important to closely monitor subjects with high levels of TG and BMI in health check-up population especially for women, because these two components are closely associated with development of hypertension, diabetes, cardiovascular disease and other metabolic diseases.

Keywords: Triglycerides, Metabolic syndrome components, Longitudinal correlation, Joint model

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Tao LX, Yang K, Liu XT, Cao K, Zhu HP, Luo YX, Guo J, Wu LJ, Li X, Guo XH. Longitudinal Associations between Triglycerides and Metabolic Syndrome Components in a Beijing Adult Population, 2007-2012. Int J Med Sci 2016; 13(6):445-450. doi:10.7150/ijms.14256. Available from http://www.medsci.org/v13p0445.htm