Int J Med Sci 2015; 12(4):306-311. doi:10.7150/ijms.11343

Research Paper

Using Vascular Closure Devices Following Out-Of-Hospital Cardiac Arrest?

Martin Christ, Katharina Isabel von Auenmueller, Jeanette Liebeton, Martin Grett, Wolfgang Dierschke, Jan Peter Noelke, Irini Maria Breker, Hans-Joachim Trappe

Department of Cardiology and Angiology, Marienhospital Herne, Ruhr - University Bochum, Germany


Objectives and Background: Despite a generally broad use of vascular closure devices (VCDs), it remains unclear whether they can also be used in victims from out-of-hospital cardiac arrest (OHCA) treated with mild therapeutic hypothermia (MTH).

Methods: All victims from OHCA who received immediate coronary angiography after OHCA between January 1st 2008 and December 31st 2013 were included in this study. The operator decided to either use a VCD (Angio-Seal™) or manual compression for femoral artery puncture. The decision to induce MTH was based on the clinical circumstances.

Results: 76 patients were included in this study, 46 (60.5%) men and 30 (39.5%) women with a mean age of 64.2 ± 12.8 years. VCDs were used in 26 patients (34.2%), and 48 patients (63.2%) were treated with MTH. While there were significantly more overall vascular complications in the group of patients treated with MTH (12.5% versus 0.0%; p=0.05), vascular complications were similar between patients with VCD or manual compression, regardless of whether or not they were treated with MTH.

Conclusion: In our study, the overall rate of vascular complications related to coronary angiography was higher in patients treated with mild therapeutic hypothermia, but was not affected by the application of a vascular closure device. Therefore, our data suggest that the use of VCDs in victims from OHCA might be feasible and safe in patients treated with MTH as well, at least if the decision to use them is individually carefully determined.

Keywords: out-of-hospital cardiac arrest, resuscitation, mild therapeutic hypothermia, coronary angiography, vascular closure device

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How to cite this article:
Christ M, von Auenmueller KI, Liebeton J, Grett M, Dierschke W, Noelke JP, Breker IM, Trappe HJ. Using Vascular Closure Devices Following Out-Of-Hospital Cardiac Arrest?. Int J Med Sci 2015; 12(4):306-311. doi:10.7150/ijms.11343. Available from