International Journal of Medical Sciences

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12 December 2017

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Int J Med Sci 2015; 12(3):234-242. doi:10.7150/ijms.10837

Review

Treatment Strategies for Aneurysms Associated with Moyamoya Disease

Lei Zhang1,2,*, Kan Xu1,*, Yandong Zhang3, Xin Wang1, Jinlu Yu1,✉

1. Department of Neurosurgery, First Hospital of Jilin University, Changchun, 130021, P.R. China
2. Department of Neurosurgery, General Hospital of Daqing Oilfield, Daqing, 163001, P.R. China
3. Department of Medicine, Third Hospital of Jilin University, Changchun, 130021, P.R. China
* Lei Zhang and Kan Xu contributed equally.

Abstract

The treatment of aneurysms associated with moyamoya disease (MMD) is difficult for neurosurgeons, and little is known of strategy options. This report constitutes a comprehensive review of the literature. We summarize the known treatments and their clinical outcomes according to the site of the aneurysm: in major arteries, peripheral arteries, moyamoya vessels, meningeal arteries, or at the site of anastomosis. The literature review indicates that the treatment of MMD-associated aneurysms varies according to the site of the aneurysm and its hemodynamic characteristics. In particular, the treatment for basilar tip aneurysms remains challenging, since both endovascular embolization and direct clipping are difficult. The potential risk for ischemia should be considered in selecting endovascular or surgical approaches. Revascularization surgery, which is important for the treatment of MMD, also determines the clinical treatment outcome of aneurysms associated with MMD.

Keywords: Moyamoya disease, aneurysms, treatment

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How to cite this article:
Zhang L, Xu K, Zhang Y, Wang X, Yu J. Treatment Strategies for Aneurysms Associated with Moyamoya Disease. Int J Med Sci 2015; 12(3):234-242. doi:10.7150/ijms.10837. Available from http://www.medsci.org/v12p0234.htm