Int J Med Sci 2014; 11(9):863-869. doi:10.7150/ijms.8912 This issue Cite

Research Paper

Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer

Jie Yang*, Yan Xia*, Yang Yang, Zheng-zheng Ni, Wen-xin He, Hai-feng Wang, Xiao-xiong Xu, Yu-ling Yang, Ke Fei, Ge-ning Jiang

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China
* Dr. Jie Yang and Yan Xia contribute equally to this work.

Citation:
Yang J, Xia Y, Yang Y, Ni Zz, He Wx, Wang Hf, Xu Xx, Yang Yl, Fei K, Jiang Gn. Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer. Int J Med Sci 2014; 11(9):863-869. doi:10.7150/ijms.8912. https://www.medsci.org/v11p0863.htm
Other styles

File import instruction

Abstract

Aims: The purpose of this study was to identify the risk factors for major adverse events of VATS (Video-Assisted Thoracic Surgery) lobectomy for primary lung cancer.

Methods: 1806 Patients (1032 males, 57.1%) planned to undergo VATS lobectomy for stage IA-IIIA lung cancer from July 2007 to June 2012. The Thoracic Morbidity and Mortality Classification TM&M system was used to evaluate the presence and severity of complications. Postoperative complications were observed during a 30-day follow up. Univariate and multivariate analysis were used to analyze the independent risk factors for major adverse events.

Results: Successful rate of VATS lobectomy was 97.6% (1763/1806). Major complications occurred in 129 patients (7.3%), with a mortality of 0.3% (5/1763). Pulmonary complications contribute up to 90.7% of the major complications and 80% of mortality. Logistic regression indicated that comorbidities, elder age ≥70y, operative time ≥240min and hybrid VATS were predictors for major adverse events (P<0.05). Hybrid and converted VATS lobectomy result in higher major adverse events compared with complete VATS, 15.1%, 20.9% and 7.4% respectively (P=0.013).

Conclusions: The overall complication rate and mortality of VATS lobectomy are low, while major complications sometimes occur. Pulmonary complications are the most common major complications and cause of mortality. Age ≥70y, comorbidities, operative time ≥240min and Hybrid VATS are predictors of major adverse events.

Keywords: Non-small cell lung cancer, VATS, Lobectomy, Major Adverse Events, Risk factor


Citation styles

APA
Yang, J., Xia, Y., Yang, Y., Ni, Z.z., He, W.x., Wang, H.f., Xu, X.x., Yang, Y.l., Fei, K., Jiang, G.n. (2014). Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer. International Journal of Medical Sciences, 11(9), 863-869. https://doi.org/10.7150/ijms.8912.

ACS
Yang, J.; Xia, Y.; Yang, Y.; Ni, Z.z.; He, W.x.; Wang, H.f.; Xu, X.x.; Yang, Y.l.; Fei, K.; Jiang, G.n. Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer. Int. J. Med. Sci. 2014, 11 (9), 863-869. DOI: 10.7150/ijms.8912.

NLM
Yang J, Xia Y, Yang Y, Ni Zz, He Wx, Wang Hf, Xu Xx, Yang Yl, Fei K, Jiang Gn. Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer. Int J Med Sci 2014; 11(9):863-869. doi:10.7150/ijms.8912. https://www.medsci.org/v11p0863.htm

CSE
Yang J, Xia Y, Yang Y, Ni Zz, He Wx, Wang Hf, Xu Xx, Yang Yl, Fei K, Jiang Gn. 2014. Risk Factors for Major Adverse Events of Video-Assisted Thoracic Surgery Lobectomy for Lung Cancer. Int J Med Sci. 11(9):863-869.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
Popup Image