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Int J Med Sci 2012; 9(3):207-212. doi:10.7150/ijms.3690

Research Paper

Congenital Bronchial Atresia: Diagnosis and Treatment

Yuqi Wang#✉, Weimin Dai#, Yu'e Sun, Xiangyang Chu, Bo Yang, Ming Zhao

Department of Thoracic Surgery, General Hospital of the People's Liberation Army, Beijing 100853, China
# Contributed equally.

Abstract

This study aimed to retrospectively summarize the clinical signs, diagnosis, and treatment of congenital bronchial atresia (CBA) in 12 patients. Chest radiographs and computed tomographic (CT) images of 12 patients with CBA treated in the Chinese People's Liberation Army General Hospital were reviewed. Analysis of chest radiographs revealed ten patients had hilar mass-like shadows and two had pneumonia-like shadows; most patients (n = 8) showed hyperlucency of the peripheral lung fields. CT revealed a mucocele in all the patients (n = 12); the mucoceles were round in four patients and club-like in eight. In 80% of the cases (n = 10), associated anomalies, including occlusions of the bronchus central to the mucocele, emphysematous changes of the peripheral lung fields, bronchogenic cyst, and anomalous branching of the bronchial tree and vascular structure were observed. CBA was detected in the right lobe in eight patients and the left lobe in the remaining four. No surgical intervention was performed in 5 CBA patients and the remaining 7 patients underwent surgery, including lobectomy in 5 patients and local resection in 2 patients. Among these 7 patients, 3 had a preoperative diagnosis of malignant disease, and the remaining 4 had severe clinical symptoms that could not be effectively treated by medicines. All patients were followed up, and none experienced obvious discomfort. CBA is a relatively rare and benign malformation disease. Chest CT is the procedure of choice for diagnosis. The presence of a bronchocele and surrounding emphysematous changes are typical radiologic findings in CBA. Surgery should be reserved only for patients with serious complications secondary to the atretic bronchus.

Keywords: bronchial atresia, lung, diagnosis, surgical treatment

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How to cite this article:
Wang Y, Dai W, Sun Y, Chu X, Yang B, Zhao M. Congenital Bronchial Atresia: Diagnosis and Treatment. Int J Med Sci 2012; 9(3):207-212. doi:10.7150/ijms.3690. Available from http://www.medsci.org/v09p0207.htm