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Int J Med Sci 2011; 8(6):501-509. doi:10.7150/ijms.8.501

Research Paper

Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management

Hideki Taniguchi1,2,✉, Toshio Sasaki2, Hisae Fujita2

1. School of Nutrition & Dietetics, Kanagawa University of Human Services, Yokosuka, Kanagawa 238-8522, Japan
2. Department of Anesthesiology, Kanagawa Cancer Center, Yokohama 241-0815, Japan


Aim: Preoperative fluid and electrolyte management is usually performed by intravenous therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for preoperative fluid and electrolyte management of surgical patients.

Methods: The study consisted of two studies, designed as a prospective observational study. In a pilot study, 20 surgical patients consumed 1000 mL of an oral rehydration solution (ORS) until 2 h before induction of general anesthesia. Parameters such as serum electrolyte concentrations, fractional excretion of sodium (FENa) as an index of renal blood flow, volume of esophageal-pharyngeal fluid and gastric fluid (EPGF), and patient satisfaction with ORT were assessed. In a follow-up study to assess the safety of ORT, 1078 surgical patients, who consumed ORS until 2 h before induction of general anesthesia, were assessed.

Results: In the pilot study, water, electrolytes, and carbohydrate were effectively and safely supplied by ORT. The FENa value was increased at 2 h following ORT. The volume of EPGF collected following the induction of anesthesia was 5.3±5.6 mL. In the follow-up study, a small amount of vomiting occurred in one patient, and no aspiration occurred in the patients.

Conclusion: These results suggest that ORT is a safe and effective therapy for the preoperative fluid and electrolyte management of selected surgical patients.

Keywords: Oral rehydration therapy, preoperative fluid and electrolytes, oral rehydration solution

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See for full terms and conditions.
How to cite this article:
Taniguchi H, Sasaki T, Fujita H. Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management. Int J Med Sci 2011; 8(6):501-509. doi:10.7150/ijms.8.501. Available from