Int J Med Sci 2011; 8(2):106-113. doi:10.7150/ijms.8.106

Research Paper

Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction

Thomas Butz* , Corinna N. Lang*, Marc van Bracht, Magnus W. Prull, Hakan Yeni, Petra Maagh, Gunnar Plehn, Axel Meissner, Hans-Joachim Trappe

Department of Cardiology and Angiology, Marienhospital Herne, Ruhr University Bochum, Hoelkeskampring 40, D-44625 Herne, Germany
* Both authors contributed equally to this work

Abstract

Aims: Strain rate imaging techniques have been proposed for the detection of ischemic or viable myocardium in coronary artery disease, which is still a challenge in clinical cardiology. This retrospective comparative study analyzed regional left ventricular function and scaring with two-dimensional strain (2DS) in the first 4 to 10 days after acute anterior myocardial infarction (AMI).

Methods and results: The study population consisted of 32 AMI patients with an LAD occlusion and successful reperfusion. The assessment of peak systolic 2DS and peak systolic strain rate (SR) was performed segment-oriented with the angle-independent speckle tracking algorithm Velocity Vector Imaging (VVI). The infarcted, adjacent and non-infarcted segments were revealed by late enhancement MRI (LE-MRI), which was used as reference for the comparison with 2DS. The infarcted segments showed a significant decrease of tissue velocities, 2DS and SR in comparison to the non-affected segments.

Conclusion: 2DS and SR as assessed by VVI seem to be a suitable approach for echocardiographic quantification of global and regional myocardial function as well as a promising tool for multimodal risk stratification after anterior AMI.

Keywords: Myocardial infarction, Two-dimensional strain, Strain rate imaging, Late Enhancement MRI

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How to cite this article:
Butz T, Lang CN, van Bracht M, Prull MW, Yeni H, Maagh P, Plehn G, Meissner A, Trappe HJ. Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction. Int J Med Sci 2011; 8(2):106-113. doi:10.7150/ijms.8.106. Available from http://www.medsci.org/v08p0106.htm