International Journal of Medical Sciences

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23 October 2017

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Int J Med Sci 2010; 7(5):309-313. doi:10.7150/ijms.7.309

Research Paper

Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less?

Hong Chang1, Yi Gong2, Jian Xu1, Zhongxue Su1, Chengkun Qin1, Zhenhai Zhang1

1. Department of General Surgery, Shandong Provincial Hospital affiliated to Shandong University, Jinan Shandong, China;
2. Department of Rehabilitation, Shandong Provincial Hospital affiliated to Shandong University, Jinan Shandong, China.

Abstract

Objective: To further delineate the clinicopathological and radiological features of solid pseudopapillary tumor (SPT) of the pancreas and summarize the surgical therapy strategy for this tumor. Methods: A retrospective review of 18 pathologically confirmed cases of SPT was performed and the clinical and pathological features, radiological findings and surgical interventions were analyzed. Results: The patients included 17 females and 1 male with a median age of 23 years. The median diameter of the lesions was 8.0 cm. Abdominal pain was the predominant complaint (8/18). The rest of the patients were asymptomatic and presented with a pancreatic mass detected incidentally. Radiological study revealed a well-demarcated mass which was composed of a solid-cystic portion. On post-contrast CT, the solid portions could be enhanced whereas the cystic parts remained unenhanced. With the preoperative diagnosis of SPT in 11 patients and pancreatic cyst, benign or malignant pancreatic tumor in the rest, pancreatic tumor resection was successfully completed. Surgical exploration findings, pathological characteristics and good prognosis of the patients with SPT, indicated its low-grade malignant potential. Conclusion: In combination with clinical findings, radiological features of SPT may help to make the correct diagnosis and differentiation from other pancreatic neoplasms. Once diagnosed, given the excellent prognosis and low-grade malignancy, less aggressive surgical resection of the primary lesion is proposed.

Keywords: Diagnosis, Pancreas, Solid pseudopapillary tumor, Surgery

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How to cite this article:
Chang H, Gong Y, Xu J, Su Z, Qin C, Zhang Z. Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less?. Int J Med Sci 2010; 7(5):309-313. doi:10.7150/ijms.7.309. Available from http://www.medsci.org/v07p0309.htm