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Int J Med Sci 2009; 6(5):258-264. doi:10.7150/ijms.6.258 This issue Cite

Research Paper

Treatment of proximal femur infections with antibiotic-loaded cement spacers

J. Kelm 1,2 ✉, P. Bohrer 3, E. Schmitt 1, K. Anagnostakos 1

1. Klinik für Orthopädie und Orthopädische Chirurgie, Universitätskliniken des Saarlandes, Homburg/Saar, Germany
2. Chirurgisch-Orthopädisches Zentrum Illingen/Saar, Germany
3. Amper Kliniken AG, Klinikum Dachau, Abteilung für Orthopädie und Unfallchirurgie, Germany

✉ Correspondence to: Dr. med. Jens Kelm, Diplom-Sportlehrer, Chirurgisch-Orthopädisches Zentrum Illingen, Rathausstr. 2, D-66557 Illingen/Saar, Germany. Tel: 0049 6841 1624520; Fax: 0049 6841 1624516; E-Mail: jk66421com

Citation:
Kelm J, Bohrer P, Schmitt E, Anagnostakos K. Treatment of proximal femur infections with antibiotic-loaded cement spacers. Int J Med Sci 2009; 6(5):258-264. doi:10.7150/ijms.6.258. https://www.medsci.org/v06p0258.htm
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Abstract

In case of periprosthetic hip infections the implantation of antibiotic-loaded PMMA spacers is accepted for an adequate treatment option. Although their indication for the treatment of destructive, bacterial infections of the proximal femur would make sense, literature data are scarce. Hence, the aim of this study was to evaluate the efficacy of antibiotic-impregnated spacers in the treatment of proximal femur infections.

In 10 consecutive patients (5 M/ 5 F, mean age 66 y.) with bacterial proximal femur infections, a femoral head/neck resection was prospectively performed with a subsequent implantation of an antibiotic-loaded spacer. The joint-specific outcome was evaluated by the Merle d´Aubigne and the Mayo hip score, the general outcome by SF-36. The time periods were divided into “infection situation”, “between stages” and meanly 1 year “after prosthesis implantation”.

The spacers were meanly implanted over 90 [155-744] days. In all cases an infection eradication could be achieved. After infection eradication, a prosthesis implantation was performed in 8 cases. The general scores showed significant increases at each time period. With regard to the dimension “pain”, both scores demonstrated a significant increase between “infection situation” and “between stages”, but no significance between “between stages” and “after prosthesis implantation”.

Spacers could be indicated in the treatment of proximal femur infections. Besides an infection eradication, a pain reduction is also possible.

Keywords: hip spacer, proximal femur infection, hip joint, antibiotic-loaded cement

Citation styles

APA
Kelm, J., Bohrer, P., Schmitt, E., Anagnostakos, K. (2009). Treatment of proximal femur infections with antibiotic-loaded cement spacers. International Journal of Medical Sciences, 6(5), 258-264. https://doi.org/10.7150/ijms.6.258.

ACS
Kelm, J.; Bohrer, P.; Schmitt, E.; Anagnostakos, K. Treatment of proximal femur infections with antibiotic-loaded cement spacers. Int. J. Med. Sci. 2009, 6 (5), 258-264. DOI: 10.7150/ijms.6.258.

NLM
Kelm J, Bohrer P, Schmitt E, Anagnostakos K. Treatment of proximal femur infections with antibiotic-loaded cement spacers. Int J Med Sci 2009; 6(5):258-264. doi:10.7150/ijms.6.258. https://www.medsci.org/v06p0258.htm

CSE
Kelm J, Bohrer P, Schmitt E, Anagnostakos K. 2009. Treatment of proximal femur infections with antibiotic-loaded cement spacers. Int J Med Sci. 6(5):258-264.

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