27 May 2019
Global reach, higher impact
Int J Med Sci 2019; 16(5):704-710. doi:10.7150/ijms.32089
Human Trabecular Meshwork Progenitors
1. Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University (the Second People's Hospital of Yunnan Province); Yunnan Eye Institute; Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008); Provincial Innovation Team for Cataract and Ocular Fundus Disease, The Second People's Hospital of Yunnan Province (2017HC010); Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China
Trabecular meshwork (TM) cells are a group of progenitors that have the ability to become adipocytes, chondrocytes and endothelial cells. Therefore, those adult corneal progenitors may be used as an effective therapy for trabecular meshwork diseases such as glaucoma, corneal endothelial dysfunctions such as blindness due to corneal endothelial dysfunction, and similar diseases. In order to promote the understanding of human trabecular meshwork progenitors, this article reviews human trabecular meshwork progenitor therapy and discusses its potential applications for curing human eye blindness.
Keywords: trabecular meshwork, progenitor, cell-based therapy, glaucoma
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How to cite this article:
Zhu Q, Zhang Y, Tighe S, Liu Y, Zhu Y, Hu M. Human Trabecular Meshwork Progenitors. Int J Med Sci 2019; 16(5):704-710. doi:10.7150/ijms.32089. Available from http://www.medsci.org/v16p0704.htm