The Limbal Epithelial Progenitors in the Limbal Niche Environment

Zhang, Yuan; Sun, Hong; Liu, Yongsong; Chen, Shuangling; Cai, Subo; Zhu, Yingting; Guo, Ping

doi:10.7150/ijms.16563

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Int J Med Sci 2016; 13(11):835-840. doi:10.7150/ijms.16563 This issue Cite

Review

The Limbal Epithelial Progenitors in the Limbal Niche Environment

Yuan Zhang^1*, Hong Sun^2*, Yongsong Liu³, Shuangling Chen¹, Subo Cai⁴, Yingting Zhu¹, Ping Guo^5✉

1. Research and Development Department, TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA
2. Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China
3. Department of Ophthalmology, Yan' An Hospital of Kunming City, Kunming, 650051, China
4. Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
5. Shenzhen Eye Hospital, School of Optometry & Ophthalmology of Shenzhen University, Shenzhen Key Laboratory of Department of Ophthalmology, Shenzhen, 518000, China
*The first two authors contributed equally to this manuscript.

Citation:

Zhang Y, Sun H, Liu Y, Chen S, Cai S, Zhu Y, Guo P. The Limbal Epithelial Progenitors in the Limbal Niche Environment. Int J Med Sci 2016; 13(11):835-840. doi:10.7150/ijms.16563. https://www.medsci.org/v13p0835.htm

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Abstract

Limbal epithelial progenitors are stem cells located in limbal palisades of vogt. In this review, we present the audience with recent evidence that limbal epithelial progenitors may be a powerful stem cell resource for the cure of human corneal stem cell deficiency. Further understanding of their mechanism may shed lights to the future successful application of stem cell therapy not only to the eye tissue, but also to the other tissues in the human body.

Keywords: Limbal epithelial progenitors, stem cell

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APA

Zhang, Y., Sun, H., Liu, Y., Chen, S., Cai, S., Zhu, Y., Guo, P. (2016). The Limbal Epithelial Progenitors in the Limbal Niche Environment. International Journal of Medical Sciences, 13(11), 835-840. https://doi.org/10.7150/ijms.16563.

ACS

Zhang, Y.; Sun, H.; Liu, Y.; Chen, S.; Cai, S.; Zhu, Y.; Guo, P. The Limbal Epithelial Progenitors in the Limbal Niche Environment. Int. J. Med. Sci. 2016, 13 (11), 835-840. DOI: 10.7150/ijms.16563.

NLM

CSE

Zhang Y, Sun H, Liu Y, Chen S, Cai S, Zhu Y, Guo P. 2016. The Limbal Epithelial Progenitors in the Limbal Niche Environment. Int J Med Sci. 13(11):835-840.

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