International Journal of Medical Sciences

Impact factor
2.399

13 December 2017

ISSN 1449-1907 News feeds of published articles

My Manuscript | My Account

Journal of Biomedicinenew

Theranostics

Journal of Cancer

Oncomedicine

International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Nanotheranostics

PubMed Central Indexed in Journal Impact Factor

Int J Med Sci 2012; 9(6):406-412. doi:10.7150/ijms.4715

Research Paper

Frequency of Pulmonary Hypertension in Patients with COPD due to Biomass Smoke and Tobacco Smoke

Bunyamin Sertogullarindan1✉, Hasan Ali Gumrukcuoglu2, Cengizhan Sezgi3, Mehmet Ata Akil2

1. Department of Pulmonary and Critical Care, Yuzuncu Yil University Medical Faculty, Turkey;
2. Department of Cardiology, Yuzuncu Yil University Medical Faculty, Turkey;
3. Department of Pulmonary and Critical Care, Dicle University Medical Faculty, Turkey.

Abstract

Objectives; Pulmonary hypertension (PH) is a common and well established complication of chronic obstructive pulmonary disease (COPD). Its presence is associated with decreased survival. This study was designed to investigate the PH frequency and its relations in hospitalized tobacco and biomass related COPD patients. Methods and Results; The study was a retrospective review of inpatients with COPD defined as a history of tobacco or biomass smoking, Pulmonary function tests (PFT) within stable status, an echocardiogram within stable status. PH was defined as systolic pulmonary artery pressure (sPAP) >35 mmHg. Of the 694 individuals, 600 had suitable aspects for inclusion of study. All Females were biomass exposer and males were tobacco smoker. The Prevalence of PH was found more frequent in females than males. It was more prominent in moderate level COPD cases (56,2% and 37,5%, P<0,002). Both groups had airflow limitation, hypercapnia and hypoxemia, but no differences were found in terms of PaCO2 and PaO2. However, FEV1 % was lower in males than females (p<0,005). On the other hand, FVC % was lower in the females compared with the males (p < 0.02). When analyzing the influence of PFT and demographic parameters on PH in separate COPD level groups, the results a bit varied among the groups. Conclusion; Our study demonstrated that PH frequency is higher in female COPD cases due to biomass smoke than in male COPD cases due to tobacco smoke. The influence of FVC % on the risk of a person having PH increased with increasing COPD level.

Keywords: COPD, Pulmonary Hypertension, Environmental pollutants, Smoking.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Sertogullarindan B, Gumrukcuoglu HA, Sezgi C, Akil MA. Frequency of Pulmonary Hypertension in Patients with COPD due to Biomass Smoke and Tobacco Smoke. Int J Med Sci 2012; 9(6):406-412. doi:10.7150/ijms.4715. Available from http://www.medsci.org/v09p0406.htm