International Journal of Medical Sciences

Impact factor
2.399

23 October 2017

ISSN 1449-1907 News feeds of published articles

My Manuscript | My Account

Journal of Genomics now in PubMed/PubMed Central. Submit manuscript...

Journal of Biomedicinenew

Theranostics

Journal of Cancer

Oncomedicine

International Journal of Biological Sciences

Journal of Genomics

Journal of Bone and Joint Infection (JBJI)

Nanotheranostics

PubMed Central Indexed in Journal Impact Factor

Int J Med Sci 2012; 9(4):306-310. doi:10.7150/ijms.4340

Research Paper

Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting

Qiang Ji1*, Qianglin Duan2*, Xisheng Wang1, Jianzhi Cai1, Yongxin Zhou1, Jing Feng1✉, Yunqing Mei1✉

1. Department of Thoracic Cardiovascular Surgery, Tongji Hospital of Tongji University, 389 Xincun Rd., Shanghai, 200065, P.R. China.
2. Department of Scientific Research, Tongji Hospital of Tongji University, 389 Xincun Rd., Shanghai, 200065, P.R. China.
* Contributed equally as the co-first author.

Abstract

Background: Ventilator dependency following coronary artery bypass grafting (CABG) is often associated with significant morbidity and mortality. However, few reports have focused on the independent risk factors for ventilator dependency following CABG. This study aimed to evaluate the independent risk factors for ventilator dependency following coronary artery bypass grafting (CABG). Methods: The relevant pre-, intra- and post-operative data of patients without a history of chronic obstructive pulmonary disease undergoing isolated CABG from January 2003 to December 2008 in our center were retrospectively analyzed. Elapsed time between CABG and extubation of more than 48 hours was defined as postoperative ventilator dependency (PVD). Results: The incidence of PVD was 13.8% (81/588). The in-hospital mortality in the PVD group was significantly higher than that in the non-PVD group (8.6% versus 2.4%, p=0.0092). Besides the length of ICU and hospital stay, PVD correlated with negative respiratory outcomes. The independent risk factors for PVD were preoperative congestive heart failure (OR=2.456, 95%CI 1.426-6.879), preoperative hypoalbuminemia (OR=1.353, 95%CI 1.125-3.232), preoperative arterial oxygen partial pressure (PO2) (OR=0.462, 95%CI 0.235-0.783) and postoperative anaemia (OR=1.541, 95%CI 1.231-3.783). Conclusions: Preoperative congestive heart failure, preoperative hypoalbuminemia, low preoperative PO2 and postoperative anaemia were identified as four independent risk factors for ventilator dependency following CABG.

Keywords: Coronary artery bypass grafting, ventilator dependency, risk factor.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Ji Q, Duan Q, Wang X, Cai J, Zhou Y, Feng J, Mei Y. Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting. Int J Med Sci 2012; 9(4):306-310. doi:10.7150/ijms.4340. Available from http://www.medsci.org/v09p0306.htm