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Int J Med Sci 2012; 9(1):20-26. doi:10.7150/ijms.9.20

Research Paper

Cystic Lesions of the Jaws - A Clinicopathological Study of 322 Cases and Review of the Literature

Esther Manor1, Leonid Kachko2, Max B. Puterman 3, George Szabo4, Lipa Bodner 5 ✉

1. Institute of Human Genetics, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel
2. Department of Pathology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel
3. Department of Laryngology Head and Neck Surgery , Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel
4. Department of Oral and Maxillofacial Surgery and Dentistry, Faculty of Dentistry, Semmelweis University, Budapest, Hungary
5. Department of Oral and Maxillofacial Surgery , Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel

Abstract

Three hundred and twenty-two patients (192 male and 130 female) with cystic lesions of the jaw were successfully diagnosed and treated. One hundred and fifty-five (48%) were radicular cysts, 80 (25%) were dentigerous cysts, 23 (7%) were odontogenic keratocyst (=keratocystic odontogenic tumor), 19 (6%) were eruption cysts, 16 (5%) were traumatic bone cysts, and 29 (9%) were non-odontogenic cysts.

There were 95 in the pediatric age group (1 month to 16 years) and 227 in the adult age group (17 years and older). Male to female ratio was 1 in the pediatric age group and 1.7 in the adult age group. The treatment modalities were: marsupialization, enucleation, enucleation with bone grafting, or resection. The distribution and characteristics of jaw cysts in children are different from those in adults. In children there is a relatively high rate of developmental cysts, whereas in adults the inflammatory cysts are more common. Following enucleation of a cystic jaw lesion, the entire surgical specimen and not only a biopsy specimen, should be examined histopathologically to prevent any possibility of an intramural squamous cell carcinoma that may be overlooked. The differences in prevalence of each type of jaw cyst during a lifetime may point toward a multifactorial polygenic pattern rather than a monogenic pattern.

Keywords: cyst, jaw bone, children, adults, genetics

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How to cite this article:
Manor E, Kachko L, Puterman MB, Szabo G, Bodner L. Cystic Lesions of the Jaws - A Clinicopathological Study of 322 Cases and Review of the Literature. Int J Med Sci 2012; 9(1):20-26. doi:10.7150/ijms.9.20. Available from http://www.medsci.org/v09p0020.htm