International Journal of Medical Sciences

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20 October 2017

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Int J Med Sci 2011; 8(7):635-639. doi:10.7150/ijms.8.635

Case Report

Multiple Aspergillus Cerebellar Abscesses in a Middle-Aged Female: Case Report and Literature Review

Sheng Chen1, Jia-Li Pu2, Jun Yu1* ✉, Jian-Min Zhang1* ✉

1. Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
2. Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
* Jun Yu and Jian-Min Zhang contributed equally to this paper.

Abstract

Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary. Here, we report the first case of multiple Aspergillus cerebellar abscesses in a 46-year-old female after one mastoidectomy, two craniectomies, and extended use of antibiotics. The possible pathogenesis of this unusual event is discussed. Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

Keywords: Aspergillus, Cerebellum, Voriconazole, Neurosurgical resection

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Chen S, Pu JL, Yu J, Zhang JM. Multiple Aspergillus Cerebellar Abscesses in a Middle-Aged Female: Case Report and Literature Review. Int J Med Sci 2011; 8(7):635-639. doi:10.7150/ijms.8.635. Available from http://www.medsci.org/v08p0635.htm