International Journal of Medical Sciences

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17 October 2017

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Int J Med Sci 2011; 8(6):461-466. doi:10.7150/ijms.8.461

Research Paper

Patient Specification Quality Assurance for Glioblastoma Multiforme Brain Tumors Treated with Intensity Modulated Radiation Therapy

H. I. Al-Mohammed

King Faisal Specialist Hospital & Research Centre, Dept. of Biomedical Physics, Riyadh 11211, Saudi Arabia

Abstract

The aim of this study was to evaluate the significance of performing patient specification quality assurance for patients diagnosed with glioblastoma multiforme treated with intensity modulated radiation therapy. The study evaluated ten intensity modulated radiation therapy treatment plans using 10 MV beams, a total dose of 60 Gy (2 Gy/fraction, five fractions a week for a total of six weeks treatment). For the quality assurance protocol we used a two-dimensional ionization-chamber array (2D-ARRAY). The results showed a very good agreement between the measured dose and the pretreatment planned dose. All the plans passed >95% gamma criterion with pixels within 5% dose difference and 3 mm distance to agreement. We concluded that using the 2D-ARRAY ion chamber for intensity modulated radiation therapy is an important step for intensity modulated radiation therapy treatment plans, and this study has shown that our treatment planning for intensity modulated radiation therapy is accurately done.

Keywords: Photon-beam dose calculation, quality assurance, intensity modulated radiation therapy, dose verification, gamma index, glioblastoma multiforme.

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How to cite this article:
Al-Mohammed HI. Patient Specification Quality Assurance for Glioblastoma Multiforme Brain Tumors Treated with Intensity Modulated Radiation Therapy. Int J Med Sci 2011; 8(6):461-466. doi:10.7150/ijms.8.461. Available from http://www.medsci.org/v08p0461.htm