Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer

Umemura, Kota; Ishioka, Shin-ichi; Endo, Toshiaki; Baba, Tsuyoshi; Ezaka, Yoshiaki; Nagasawa, Kunihiko; Takahashi, Madoka; Mizuuchi, Masahito; Iwami, Nanako; Adachi, Hidefumi; Takeda, Noriko; Tamagawa, Mitsuharu; Saito, Tsuyoshi

doi:10.7150/ijms.7.260

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Int J Med Sci 2010; 7(5):260-266. doi:10.7150/ijms.7.260 This issue Cite

Research Paper

Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer

Kota Umemura¹, Shin-ichi Ishioka¹ ^✉, Toshiaki Endo¹, Tsuyoshi Baba¹, Yoshiaki Ezaka¹, Kunihiko Nagasawa¹, Madoka Takahashi¹, Masahito Mizuuchi¹, Nanako Iwami¹, Hidefumi Adachi¹, Noriko Takeda¹, Mitsuharu Tamagawa², Tsuyoshi Saito¹

1. Department of Obstetrics and Gynecology, Sapporo Medical University, Sapporo Hokkaido, Japan
2. Department of Radiology, Sapporo Medical University, Sapporo Hokkaido, Japan

Citation:

Umemura K, Ishioka Si, Endo T, Baba T, Ezaka Y, Nagasawa K, Takahashi M, Mizuuchi M, Iwami N, Adachi H, Takeda N, Tamagawa M, Saito T. Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer. Int J Med Sci 2010; 7(5):260-266. doi:10.7150/ijms.7.260. https://www.medsci.org/v07p0260.htm

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Abstract

Background. Vaginal radical trachectomy (RT) ligates and cuts several arteries supplying the uterus. Changes of blood supply to the uterus in two patients who experienced pregnancy and delivery were studied by using 3-D CT scanning. Effects of changes of blood supply to the uterus on the pregnancy courses were also examined.

Methods. Vascular distribution in the uterus was studied in two patients who received vaginal RT after delivery. Effects of changes of vascular distribution after vaginal RT were studied with respect to pregnancy courses and cervical functions.

Results. New arterial vascularization from the ascending branches of uterine arteries or other arteries occurred, and these new vessels seemed to supply blood to the remaining cervix. Differences of fetal growth and histopathological changes in the placenta between the two patients could not be detected.

Conclusion. Ligation and cutting of several supplying arteries by RT induces new areterial vascularization and it does not seem to affect fetal growth and placental function.

Keywords: Radical trachelectomy, uterine cervical cancer, 3-D CT scanning

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APA

Umemura, K., Ishioka, S.i., Endo, T., Baba, T., Ezaka, Y., Nagasawa, K., Takahashi, M., Mizuuchi, M., Iwami, N., Adachi, H., Takeda, N., Tamagawa, M., Saito, T. (2010). Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer. International Journal of Medical Sciences, 7(5), 260-266. https://doi.org/10.7150/ijms.7.260.

ACS

Umemura, K.; Ishioka, S.i.; Endo, T.; Baba, T.; Ezaka, Y.; Nagasawa, K.; Takahashi, M.; Mizuuchi, M.; Iwami, N.; Adachi, H.; Takeda, N.; Tamagawa, M.; Saito, T. Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer. Int. J. Med. Sci. 2010, 7 (5), 260-266. DOI: 10.7150/ijms.7.260.

NLM

CSE

Umemura K, Ishioka Si, Endo T, Baba T, Ezaka Y, Nagasawa K, Takahashi M, Mizuuchi M, Iwami N, Adachi H, Takeda N, Tamagawa M, Saito T. 2010. Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer. Int J Med Sci. 7(5):260-266.

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