International Journal of Medical Sciences

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19 October 2017

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Int J Med Sci 2010; 7(5):260-266. doi:10.7150/ijms.7.260

Research Paper

Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer

Kota Umemura1, Shin-ichi Ishioka1 , Toshiaki Endo1, Tsuyoshi Baba1, Yoshiaki Ezaka1, Kunihiko Nagasawa1, Madoka Takahashi1, Masahito Mizuuchi1, Nanako Iwami1, Hidefumi Adachi1, Noriko Takeda1, Mitsuharu Tamagawa2, Tsuyoshi Saito1

1. Department of Obstetrics and Gynecology, Sapporo Medical University, Sapporo Hokkaido, Japan
2. Department of Radiology, Sapporo Medical University, Sapporo Hokkaido, Japan

Abstract

Background. Vaginal radical trachectomy (RT) ligates and cuts several arteries supplying the uterus. Changes of blood supply to the uterus in two patients who experienced pregnancy and delivery were studied by using 3-D CT scanning. Effects of changes of blood supply to the uterus on the pregnancy courses were also examined.

Methods. Vascular distribution in the uterus was studied in two patients who received vaginal RT after delivery. Effects of changes of vascular distribution after vaginal RT were studied with respect to pregnancy courses and cervical functions.

Results. New arterial vascularization from the ascending branches of uterine arteries or other arteries occurred, and these new vessels seemed to supply blood to the remaining cervix. Differences of fetal growth and histopathological changes in the placenta between the two patients could not be detected.

Conclusion. Ligation and cutting of several supplying arteries by RT induces new areterial vascularization and it does not seem to affect fetal growth and placental function.

Keywords: Radical trachelectomy, uterine cervical cancer, 3-D CT scanning

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
How to cite this article:
Umemura K, Ishioka Si, Endo T, Baba T, Ezaka Y, Nagasawa K, Takahashi M, Mizuuchi M, Iwami N, Adachi H, Takeda N, Tamagawa M, Saito T. Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer. Int J Med Sci 2010; 7(5):260-266. doi:10.7150/ijms.7.260. Available from http://www.medsci.org/v07p0260.htm