A k2A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt's man [Abstract]

International Journal of Medical Sciences

24 May 2013

ISSN 1449-1907

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Int J Med Sci 2009; 6(6):301-304. doi:10.7150/ijms.6.301

Short Research Communication

A k₂A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt's man

Melissa S. Doud¹, Reni Grimes-Zeppegno⁴, Enrique Molina⁴, Nancimae Miller⁴, Danajeyan Balachandar³, Lisa Schneper², Robert Poppiti⁴, Kalai Mathee^{2 ✉}

1. Department of Biological Sciences, College of Arts and Sciences, Florida International University, Miami, Florida 33199;
2. Department of Molecular Microbiology and Infectious Diseases, College of Medicine, Florida International University, Miami, Florida 33199;
3. Department of Agricultural Microbiology, Tamil Nadu Agricultural University, Coimbatore 641 003, India,
4. Department of Pathology, Mount Sinai Medical Center - FIU College of Medicine, Miami Beach, FL33140, USA

Abstract

Klebsiella pneumoniae isolated in community-acquired pneumonia is increasingly found in primary pyogenic liver abscesses. The presence of magA in K. pneumoniae has been implicated in hypermucoviscosity and virulence of liver abscess isolates. The K2 serotype has also been strongly associated with hypervirulence. We report the isolation of non-magA, K2 K. pneumoniae strain from a liver abscess of a Saint Kitt's man who survived the invasive syndrome.

Keywords: Klebsiella pneumoniae, magA, 16S rRNA, k₂A, dengue fever

How to cite this article:
Doud MS, Grimes-Zeppegno R, Molina E, Miller N, Balachandar D, Schneper L, Poppiti R, Mathee K. A k₂A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt's man. Int J Med Sci 2009; 6(6):301-304. doi:10.7150/ijms.6.301. Available from http://www.medsci.org/v06p0301.htm